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A Semi-Empirical Tire-Model for Transient Combined-Slip Forces

This paper presents a semi-empirical combined-slip tiremodel including transient behavior. The method relies on theassumption that the transient behavior is a result from the dynamicdeformation of the tire carcass and that the interaction between thelateral and longitudinal slip and forces can be explained by thedeformation of the rubber treads. The deformation of the tire carcassmakes the tread s

Lidocaine for treatment of severe seizures in newborn infants. II. Blood concentrations of lidocaine and metabolites during intravenous infusion

The blood concentrations of lidocaine and its main active metabolites, methylethylglycinexylidide (MEGX) and glycinexylidide (GX), were measured in 24 newborn infants during anticonvulsive treatment with an iv infusion of lidocaine. After a bolus dose of 1.5-2.2 mg/kg and continuous infusion of lidocaine (4.7-6.3 mg/kg/h) there was accumulation of the drug and MEGX within 24 h. After termination o

Degree of in vivo inhibition of human gastric and pancreatic lipases by Orlistat (Tetrahydrolipstatin, THL) in the stomach and small intestine.

BACKGROUND AND AIMS: Orlistat, a lipase inhibitor, strongly inhibits the activities of all gastric/pancreatic lipases except pancreatic phospholipase A(2)in vitro. In clinical use, for obesity treatment, it induces a variable degree of weight loss and steatorrhoéa. The aim of this study was to examine the degree of in vivo inhibition of individual gastric/pancreatic lipases by Orlistat in man, whe

Exploring Bottlenecks in Market-Driven Requirements Management Processes with Discrete Event Simulation

This paper presents a study where a market-driven requirements management process is simulated. In market-driven software development, generic software packages are released to a market with many customers. New requirements are continuously issued, and the objective of the requirements management process is to elicit, manage, and prioritize the requirements. In the presented study, a specific requ

No title

Abstract in Danish Afhandlingens hovedproblemstillinger er: Hvilken betydning har det for danske socialarbejderes vurderinger og handlinger i børnefamiliearbejdet, at et barn og dets familie ikke er etniske danskere? Denne problemstilling undersøges gennem tre empiriske undersøgelser: Familieplejeundersøgelsen består af en journalundersøgelse af 44 anbragte etniske minoritetsbørns journaler samt The dissertation studies how social workers ensure continuity in relation to the individual child's background when placing and working with children of ethnic minority background in care. This is studied through 44 sets of case study notes from a foster-care association and interviews with 10 foster-care consultants. These two types of data are analysed through three perspectives: a continuity pe

Life satisfaction among informal caregivers in comparison with non-caregivers.

Being a caregiver with responsibility for someone with reduced health compared with not being a caregiver may mean different views of life satisfaction. Knowledge of what leads to reduced life satisfaction in caregivers may be helpful in interventions. Informal caregivers gainfully employed or not, aged 50–89 years, were studied with regard to life satisfaction depending on the extent of caregivin

Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage

The heterogeneity of the components of proteoglycan aggregates, their stoichiometry within the aggregate and the aggregates' stability was investigated in normal human articular cartilage specimens (age-range newborn to 63 years). Proteoglycans were extracted from tissue by sequentially extracting them with PBS alone, PBS containing oligosaccharides of hyaluronan, and PBS containing solutions of i

Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells

Glycosylation defects occur in several human diseases. In IgA nephropathy, IgA1 contains O-glycans that are galactose-deficient and consist mostly of core 1 alpha2,6 sialylated N-acetylgalactosamine, a configuration suspected to prevent beta1,3 galactosylation. We confirmed the same aberrancy in IgA1 secreted by the human DAKIKI B cell line. Biochemical assays indicated CMP-NeuAc:GalNAc-IgA1 alpha

Provitamins and vitamins D2 and D3 in Cladina spp. over a latitudinal gradient: possible correlation with UV levels

Provitamin D2, vitamin D2 and vitamin D3 were identified in the thallus of a lichen species, Cladina arbuscula (Wallr.) Hale and W.L. Culb. The identification of vitamin D3 was supported by: (1) co-chromatography in both reverse and straight phase HPLC (high performance liquid chromatography), (2) ultraviolet absorption spectrum, and (3) molecular ion peaks demonstrated by ESI (electrospray ionisa