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Compact, folded multi-pass cells for energy scaling of post-compression

Combining high peak and high average power has long been a key challenge of ultrafast laser technology, crucial for applications such as laser-plasma acceleration and strong-field physics. A promising solution lies in post-compressed ytterbium lasers, but scaling these to high pulse energies presents a major bottleneck. Post-compression techniques, particularly Herriott-type multi-pass cells (MPCs

Energy scaling in a compact bulk multi-pass cell enabled by Laguerre-Gaussian single-vortex beams

We report pulse energy scaling enabled by the use of Laguerre-Gaussian single-vortex (LG0,l) beams for spectral broadening in a sub-40 cm long Herriott-type bulk multi-pass cell. Beams with orders l=1−3 are generated by a spatial light modulator, which facilitates rapid and precise reconfiguration of the experimental conditions. 180 fs pulses with 610 uJ pulse energy are post-compressed to 44 fs u

Sphingosine-1-Phosphate, a Marker of Endothelial Injury and Disease Severity in Preeclampsia

BACKGROUND: Preeclampsia is a hypertensive pregnancy disorder marked by endothelial damage. Healthy endothelium is covered by a protective glycocalyx layer, which, when degraded, releases detectable products into the blood. Sphingosine-1phosphate (S1P) is a cardiovascular biomarker involved in glycocalyx preservation, linked to placentation and preeclampsia development. The study aimed to test the

Surgery for primary ventral hernias and risk of postoperative pain, nausea : a population-based register study

Purpose: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias. Method: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register. Results: Altogether 2064

Läkarstudenters beredskap för vetenskapligt baserat arbete

Several of the requirements for obtaining a medical degree according to the Swedish Higher Education Ordinance illustrate the scientific basis of the profession, and systematic reviews as well as health technology assessments (HTA) constitute cornerstones in evidence-based medicine. In this study, medical students' experience of scientific education related to the profession was explored, and thei

BORTOM KOLKREDITER: FÖR ETT MATSYSTEM INOM PLANETENS GRÄNSER

Svensk Kolinlagring och Lunds universitet (LUCSUS) samlade 19 personer för en workshop på Torsåker gård i syfte att diskutera styrmedel och strategier för att öka kolinlagringen i jordbruksmark, och hur dessa verktyg skulle kunna utformas för att stödja en omställning till ett socialt och ekologiskt hållbart matsystem. Deltagarna representerade olika delar och nivåer av matsystemet och bidrog med

FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization

Objective: This study aimed to compare cumulative [fresh and frozen embryo transfers from one ovarian stimulation (OS) cycle] pregnancy and live birth rates in women for whom the choice between recombinant FSH (rFSH) and urinary FSH (uFSH) for OS was linked to FSH receptor (FSHR) N680S genotype and compared these to non-genotyped controls.Methods: To define the optimal combination of FSH type and

Impact of maternal prepregnancy body mass index on neonatal outcomes following extremely preterm birth

Objective: Extremes of prepregnancy maternal BMI increase neonatal mortality and morbidity at term. They also increase the risk of extremely preterm (EP, i.e., <27 weeks' gestational age) births. However, the association between maternal BMI and outcomes for EP babies is poorly understood. Methods: We used a cross-country design, bringing together the following three population-based, prospective,

Soil nitrous oxide emissions from global land ecosystems and their drivers within the LPJ-GUESS model (v4.1)

Nitrogen (N) transformation processes by soil microbes account for significant nitrous oxide (N2O) emissions from natural ecosystems and cropland. However, understanding and quantifying global soil N2O emissions and their responses to changing environmental conditions remain challenging. Here, we implemented a soil nitrification–denitrification module into the dynamic vegetation model LPJ-GUESS to

CVRAE QVOT VIVITIS ANNOS NON SIT : Time Expressions in Neo-Latin Funerary Inscriptions of Sweden

One of the most frequent elements of a funeral inscription is chronological data concerning the biography of the diseased. The present paper focuses on time-related collocations used in Neo-Latin funerary inscriptions of Sweden. Unlike medieval inscriptions, the length of the life lived and duration of important offices held are often indicated, sometimes approximately. The classical dating with K

Greenwashing : A critical realist approach to the study of false ecological claims

Greenwashing is on the rise as a strategy for maintaining business-as-usual through false ecological claims. This paper articulates an approach to the study of greenwashing guided by the philosophy of critical realism. In its first move, it identifies greenwashing as depending on the possibility of socially conflating the relation between transitive and intransitive objects of knowledge. The paper

Association between clinical outcome and microbiological findings in peritonsillar abscess - an observational study

Background: Previous studies on causative pathogens in peritonsillar abscesses have yielded varying results. However, Group A streptococci (GAS) and Fusobacterium necrophorum have been identified frequently. The aim of this study was to investigate pathogens in peritonsillar abscesses in patients tested for both ß-hemolytic streptococci and F. necrophorum, and to investigate associations between p

Bloodstream infections at a tertiary hospital in the Gambia - a one-year retrospective study

Introduction: Antimicrobial resistance is a significant global health concern, particularly in western Sub-Saharan Africa. This study describes causes of bloodstream infections and antimicrobial resistance at a tertiary hospital in The Gambia. Methods: This retrospective analysis included all blood cultures performed at the Edward Francis Small Teaching Hospital, Banjul, The Gambia, from September

Cantú Syndrome With Acromegaloid Features, Multiple Endocrinopathies, and Infection Susceptibility

Cantú syndrome involves fetal polyhydramniosis, congenital hypertrichosis, and macrosomia. Distinctive features include acromegaloid features with broad nasal bridge and macroglossia as well as cardiac abnormalities, including patent ductus arteriosus. We present a case in a male patient, who presented with cardiac abnormalities in childhood, but was diagnosed with the syndrome in adulthood after

Petrography and field relationships of impact lithologies at the Gardnos impact structure, Norway

New mapping and laboratory studies of the impactites at the Gardnos impact structure (Norway) show a variety of impact-deformed rocks. Our mapping and petrographic analyses have subdivided these breccias into three distinct categories: (a) melt-bearing sueivitic breccias, melt-bearing polymict breccias; (b) melt-free, polymict lithic impact breccias; and (c) monomict lithic impact breccias. This i

Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

We analyzed the structural and material properties of small interfering RNA (siRNA)-loaded lipid-polymer hybrid nanoparticles (LPNs) containing ionizable lipidoid and poly(dl-lactic-co-glycolic acid) (PLGA) using small-angle X-ray scattering, cryogenic transmission electron microscopy, polarized light microscopy, the Langmuir monolayer methodology, differential scanning calorimetry, and attenuated

Ephemeral space sanctification and trespassing gender boundaries in a Muslim city

A distinct feature of Muslim cities is demarcated separation between zones of public economic and private domestic activities. Such spatial distinction has been the organic extension of a social structure with limited presence of women in public zones. However, separation of spaces in the Muslim city and the way it is utilized, shaped and reproduced by men and women is not a simple case of dividin