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Cell line dependent expression of EpCAM influences the detection of circulating tumor cells with CellSearch

OBJECTIVES: The existence of circulating tumor cells has emerged as an important factor for prognosis and survival. The CellSearch method is the only circulating tumor cell detection method approved by the US Food and Drug Administration for clinical use. It relies on the detection of EpCAM (epithelial cell adhesion molecule) and is approved for colon cancer, breast cancer and prostate cancer. We

Between a Rock and a Hard Place : New Evidence on the Relationship between Ownership and Voluntary Disclosure

Combining two Swedish databases with unique strengths I show empirically that stray firms, i.e. those lacking a controlling owner, have lower voluntary disclosure in financial reports (that is, information provided beyond what is formally required). This suggests managers prefer to withhold information to maximize their discretion over corporate policies. I also show that disclosure initially incr

Institutional Logics Perspective on Diaconia

The purpose of this chapter is to use an ecclesiological description of the history of Diaconia to identify some sometimes contrasting and even competing institutional logics within the practice of diaconal work i Sweden.

Lesbian, gay and bisexual parents' experiences of nurses' attitudes in child health care-A qualitative study

AIMS AND OBJECTIVES: To describe lesbian, gay and bisexual parents' experiences of nurses' attitudes in child healthcare.BACKGROUND: Lesbian, gay and bisexual people are often reluctant to disclose their gender identity for fear of discrimination. This fear may lead to avoidance of healthcare for themselves or their children and may negatively affect families' health and well-being.DESIGN: A quali

Sleep Habits and Nighttime Texting Among Adolescents

The aim of this study was to examine sleep habits (i.e., bedtimes and rising times) and their association with nighttime text messaging in 15- to 17-year-old adolescents. This cross-sectional study analyzed data from a web-based survey of adolescent students attending secondary schools in southern Sweden ( N = 278, 50% female). Less than 8 hr of time in bed during school nights was significantly a

Interconnected hardware infrastructure resource control

A physical network node controls allocation and/or deallocation of resources of an interconnected hardware infrastructure. The physical network node determines a number of requests currently queued at a first service node of a plurality of serially-connected service nodes at a current time. The plurality of serially-connected service nodes supports a packet flow using resources of the interconnect

‘Nordicness’ in Scandinavian Music : A Complex Question

The question of what makes ‘Nordic’ music distinctive is a matter of some dispute. Does it exist? Or, in what ways is it able to manifest itself? Like nationality, it is a construction of identity that emerges through discourses on music and on Nordicness. Essentially it is an open signifier, as concepts of Nordicness can be identified either with something dark, cold and obscure or as something r

How Exceptional Must ‘Very Exceptional’ Be? Non-Refoulement, Socio-Economic Deprivation and Paposhvili V. Belgium

Since N. v. the United Kingdom, an exceptionally high threshold has been applied to migrants who try to avoid expulsion in order to continue to receive medical assistance in the returning state. With Paposhvili v. Belgium, the Grand Chamber of the ECtHR recognized the ensuing protection gap and modified the standards. These modifications imply a small opening of the ‘very exceptional’ standard to

A stark choice : Domestic violence or deportation? The immigration status of victims of domestic violence under the istanbul convention

The Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence (the Istanbul Convention) is a relatively recent treaty that has the objective to protect women against all forms of violence and to design a comprehensive framework of measures for achieving this aim. Migrant women are of special concern given the awareness that when their migration status is

Populism, Exceptionality and the Right of Migrants to Family Life Under the European Convention on Human Rights

The populist turn in national and international politics includes one common question across countries: curbing immigration and limiting the rights of migrants. In the light of these restrictive tendencies, the questions that this article seeks to address are: whether and how the European Convention on Human Rights (ECHR), as interpreted by the European Court of Human Rights (ECtHR), can be a poin

Frequency of early vascular aging and associated risk factors among an adult population in Latin America : the OPTIMO study

The main objective was to estimate the frequency of early vascular aging (EVA) in a sample of subjects from Latin America, with emphasis in young adults. We included 1416 subjects from 12 countries in Latin America who provided information about lifestyle, cardiovascular risk factors (CVRF), and anthropometrics. We measured pulse wave velocity (PWV) as a marker of arterial stiffness, and blood pre

Psychotropic and anti-dementia treatment in elderly persons with clinical signs of dementia with Lewy bodies : A cross-sectional study in 40 nursing homes in Sweden

Background: Elderly persons with a dementia diagnosis often suffer from different neuropsychiatric symptoms (NPS) such as delusions, hallucinations, depression, anxiety, irritability and agitation. Currently, the medical treatment for NPS consists mostly of psychotropic medication such as hypnotics/sedatives, anxiolytics and antipsychotics. In elderly persons with dementia, usage of antipsychotics

Impact of treatment strategy and physical performance on future knee-related self-efficacy in individuals with ACL injury

Background: In people with anterior cruciate ligament (ACL) injury, high self-efficacy facilitates recovery, indicated by improved muscle function, reduced knee symptoms and increased physical activity. Impact of treatment on future self-efficacy is however not well investigated. The aims of the study were to 1) investigate knee-related self-efficacy 6 years after acute ACL injury in patients trea

The effect of endoscopic sinus surgery on quality of life and absenteeism in patients with chronic rhinosinuitis - A multi-centre study

Background: Chronic rhinosinusitis with and without nasal polyps (CRSw/sNP) are common conditions decreasing health-related quality of life (HRQOL). Individual symptoms capable of predicting outcome after endoscopic sinus surgery (ESS) are poorly defined, and the indirect costs of CRS is rarely reported in Europe. Methodology: Patients with CRSw/sNP admitted for ESS were prospectively enrolled. Pa