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Automating operating procedure synthesis for batch processes: Part I. Knowledge representation and planning framework

Automating the synthesis of operating procedures for batch processes is very valuable as plant personnel often spend considerable amount of time and effort in preparing and verifying them for correctness and completeness. Towards this goal, a framework for automating operating procedure synthesis for batch processes is proposed in this paper. We propose an approach based on Grafcet, a discrete eve

Stability Analysis of Discrete-Time Adaptive Control Schemes

The stability properties of a fairly general diserete-time adaptive control scheme are analyzed. Sufficient conditions forL^{\infty}stability in the presence of disturbances are given. The stability results are used to prove convergence of the process outputs in the disturbance-free case, without requiring any a priori stability assumption.

Production and activation of recombinant hK2 with propeptide mutations resulting in high expression levels

Human glandular kallikrein 2 (hK2) is a serine protease expressed mainly by the prostate gland with 80% identity in primary structure to prostate specific antigen (PSA). hK2 has proven to be a useful marker of prostate cancer which can be used in combination with PSA to better discriminate between prostate cancer and benign prostate hyperplasia. The studies on hK2 have been hampered by its very lo