Published 28 November 2019 When analyzing effect heterogeneity, the researcher commonly opts for stratification or a regression model with interactions. While these methods provide valuable insights, their usefulness can be somewhat limited, since they typically fail to take into account heterogeneity with respect to many dimensions simultaneously, or give rise to models with complex appearances.

https://www.lupop.lu.se/article/assessing-heterogeneous-effects-and-their-determinants-estimation-potential-outcomes - 2025-03-18

Published 28 November 2019 Data on the 4466 trauma patients in the registry were analysed. Out of 59 variables, most (n = 51; 86.4%) were missing less than 20% of observations. There were 808 (18.1%) patients missing at least one of the first in-hospital physiological observations. Hospital death was associated with missing in-hospital physiological data (adjusted OR 1.4; 95% CI 1.02–2.01; p = 0.0

https://www.lupop.lu.se/article/establishing-multicentre-trauma-registry-india-evaluation-data-completeness - 2025-03-18

Published 29 November 2019 According to rough estimates, there are approximately 150,000 rare disease patients in Slovenia (out of a total population of 2 million). Despite the absence of accurate epidemiological data on their status, these figures reveal the great importance of this area for the Slovenian healthcare system. New publication in Orphanet Journal of Rare Diseases

https://www.lupop.lu.se/article/development-pilot-rare-disease-registry-focus-group-study-initial-steps-towards-establishment-rare - 2025-03-18

Published 29 November 2019 The study aim was to report survival and morbidity of all patients in Sweden with peritoneal mesothelioma treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as well as investigate whether the survival has increased on a population level since this treatment was nationalized 2011. Study data were collected from the Swedish HIPEC

https://www.lupop.lu.se/article/peritoneal-mesothelioma-sweden-population-based-study - 2025-03-18

Published 30 November 2019 Regulators increasingly rely on registries for decision making related to high‐risk medical devices in the United States. However, the limited uniform standards for registries may create substantial variability in registry implementation and utility to regulators. We surveyed the current landscape of US cardiovascular device registries and chart the extent of inconsisten

https://www.lupop.lu.se/article/landscape-cardiovascular-device-registries-united-states - 2025-03-18

Published 30 November 2019 Survey response rate was 98% (54/55). Overall, 57% perceived that using registry data saved research staff time in the current study, and 74% perceived that it would save time in future studies; 55% noted significant upfront time in developing a methodology for extracting registry data. Survey recommendations included simplifying data extraction processes and tailoring t

https://www.lupop.lu.se/article/lessons-learned-use-clinical-registry-data-multi-centre-prospective-study-pediatric-heart-network - 2025-03-18

Published 1 December 2019 Using a continuous exposure variable that is measured with random error in a univariable linear regression model leads to regression dilution bias: the observed association between the exposure and outcome is smaller than it would be if the true value of the exposure could be used. A repeatability sub-study, where a sample of study participants have their data measured ag

https://www.lupop.lu.se/article/reflection-modern-methods-calculating-sample-size-repeatability-sub-study-correct-measurement-error - 2025-03-18

Published 1 December 2019 Recently, King et al.1 assessed the effect of disability on mental health through bullying in adolescents using a causal mediation analysis method developed by Valeri and VanderWeele2 in which exposure–mediator interactions are allowed. In the latter method, one can only handle time-fixed exposure and mediator, and, for this reason, the authors only used the exposure in w

https://www.lupop.lu.se/article/methodological-point-mediation-analysis - 2025-03-18

Published 2 December 2019 In healthcare, we have kept notes on people with diseases for over 4000 years. These have been a combination of subjective commentary and objective measurement. In the past 30 years recording data on patients has been systematised through disease registries and electronic patient records (EPR). We now have extensive registries in many diseases with robust cross-sectional

https://www.lupop.lu.se/article/using-registries-research-cf-how-can-we-be-sure-about-outputs - 2025-03-18

Published 2 December 2019 The purpose of this paper is to understand what role researchers assign to online representations on the new digital communication sites that have emerged, such as Academia, ResearchGate or Mendeley. New publication in emerald insight

https://www.lupop.lu.se/article/researchers-online-visibility-tensions-visibility-trust-and-reputation - 2025-03-18

Published 27 November 2019 With the most important stories from Nordic section of European Open Science Cloud (EOSC). Read more here.

https://www.lupop.lu.se/article/first-issue-eosc-nordic-newsletter - 2025-03-18

Published 28 November 2019 Bibsamkonsortiet tecknar ett läs- och publiceringsavtal med det vetenskapliga förlaget Elsevier. Det innebär att svenska forskare nu åter får tillgång till förlagets drygt två tusen tidskrifter. Dessutom kommer alla svenska forskningsartiklar kunna publiceras omedelbart öppet tillgängligt (open access). Läs mer här.

https://www.lupop.lu.se/article/nytt-avtal-med-elsevier - 2025-03-18

Published 12 December 2017 Today, FORMAS announced the urgent grants for 2018 Last day of application: Any time during the year, until 08/11/2018Day of decision: Continuously during the year, last day of decision is 15/01/2019An urgent grant application can be submitted for any scientific discipline; the humanities, natural sciences, social sciences and technological sciences, and may also include

https://www.lupop.lu.se/article/formas-urgent-grants - 2025-03-18

Published 29 November 2019 Hur bör den svenska forskningspolitiken utformas för att stärka forskningen, bidra till att lösa dagens samhällsutmaningar och skapa ny kunskap för en klokare värld? Se en inspelning från Vetenskapsrådets konferens på Stockholm Waterfront 20 november. Läs mer här.

https://www.lupop.lu.se/article/forskningspolitiska-dagen-2019-0 - 2025-03-18

Published 3 December 2019 Work histories generally cover all jobs held for ≥1 year. However, it may be time and cost prohibitive to conduct a detailed exposure assessment for each such job. While disregarding short-term jobs can reduce the assessment burden, this can be problematic if those jobs contribute important exposure information towards understanding disease aetiology. New publication in A

https://www.lupop.lu.se/article/characterizing-short-term-jobs-population-based-study - 2025-03-18

Published 3 December 2019 There is a growing interest in using health care (HC) data to produce epidemiological surveillance indicators such as incidence. Typically, in the field of cancer, incidence is provided by local cancer registries which, in many countries, do not cover the whole territory; using proxy measures from available nationwide HC databases would appear to be a suitable approach to

https://www.lupop.lu.se/article/sound-use-health-care-data-epidemiology-evaluation-calibration-model-count-data-application - 2025-03-18

Published 4 December 2019 The association between socio-economic position and health is believed to be mediated, in part, by psycho-social comparison of one’s situation with that of others. But with whom? Possibilities include family, friends, elites, or even those in other countries or in previous times. So far, there has been almost no research on whether the reference point matters. New publica

https://www.lupop.lu.se/article/compared-whom-reference-groups-socio-economic-comparisons-and-self-reported-health-34-countries - 2025-03-18

Published 4 December 2019 The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey.

https://www.lupop.lu.se/article/esc-eorp-euro-endo-european-infective-endocarditis-registry - 2025-03-18

Published 5 December 2019 Obesity defined as increased BMI is commonly associated with higher revision rates following total knee arthroplasty (TKA). We examined the effect of BMI on the rate of revision after TKA, for both infection and other reasons, and analyzed weight and height separately to provide better understanding of the risk profile. New publication in Journal Acta Orthopaedica

https://www.lupop.lu.se/article/weight-and-height-separated-provide-better-understanding-bmi-risk-revision-after-total-knee - 2025-03-18

Published 5 December 2019 In recent years, epidemiologists have increasingly sought to employ genetic data to identify ‘causal’ relationships between exposures of interest and various endpoints – an instrumental variable approach sometimes termed Mendelian randomization. However, this approach is subject to all of the limitations of instrumental variable analysis and to several limitations specifi

https://www.lupop.lu.se/article/genetic-instrumental-variable-analysis-time-call-mendelian-randomization-what-it-example-alcohol-and - 2025-03-18