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Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.medicine.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-10-21

Modern imaging techniques allows researchers to map the structure of the smallest components of cells, such as proteins. By understanding what proteins look like and how they interact with their surroundings, researchers can find keys to more effective drug therapies. In a study led from Lund University, researchers have mapped the structure of a channel in the cell membrane that regulates the tra

https://www.medicine.lu.se/article/mapping-aquaporins-water-channels-cell-membranes - 2025-10-21

During the foetal stage, a number of so-called cell programs run that are vital to the development of the foetus. In a study published in Cell Reports, researchers from Lund University demonstrate that one of these foetal programs appears to protect against acute myeloid leukaemia (AML). “We have used an experimental mouse model that always results in this type of leukaemia. The interesting thing

https://www.medicine.lu.se/article/new-insights-foetal-development-may-protect-against-leukaemia - 2025-10-21

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamine nerve cells which are lost in the p

https://www.medicine.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-10-21

Is it possible to know exactly where to point a microscope in order to capture the precise moment a bacterium or a virus infects a cell? In order to take high resolution microscopic images of living biological material, you need to know exactly where to point the microscope. Researchers at Lund University in Sweden have now developed a software solution for smart, data-driven microscopy, which mak

https://www.medicine.lu.se/article/smart-microscopy-works-out-where-take-picture - 2025-10-21

Do you want to learn more about medical humanities? Birgit Rausing Centre for Medical Humanities is Lund University's youngest interdisciplinary knowledge centre. Now the centre has a new website - and a blog.  Website address: www.medical-humanities.lu.se Blog address: med-hum-en.blogg.lu.se Welcome to visit the Birgit Rausing Centre online!

https://www.medicine.lu.se/article/visit-new-website-about-medical-humanities - 2025-10-21

Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major nexus of gene expression regul

https://www.medicine.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-10-21

Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. One of these researchers is neuroscientist Oskar Hansson, who will use blood tests for rapid screening of drugs in the treatment of Alzheimer’s disease. The European Rese

https://www.medicine.lu.se/article/erc-advanced-grant-alzheimers-research - 2025-10-21

Swedish obstetricians and gynecologists are noticeably more emotionally stable and conscientious compared to the majority of the Swedish population. Based on the doctors' personalities, their decision-making styles differ in emergency situations. The research study from Lund University is now published in Scientific Reports. Personality is usually summarized in five traits - the so-called "big fiv

https://www.medicine.lu.se/article/obstetricians-more-emotionally-stable-most - 2025-10-21

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study led from Lund University in Sweden now shows how two molecular mechanisms can work together make the bacterium extra resistant. “Using this

https://www.medicine.lu.se/article/revealed-molecular-superpower-antibiotic-resistant-bacteria - 2025-10-21

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice. Many antibodies used to treat covid infection during the pandemic have been so-called neutralizin

https://www.medicine.lu.se/article/cocktail-modified-antibodies-provides-strong-effect-against-sars-cov-2 - 2025-10-21

Almost 14 million viewers have watched Anils Seth’s TED Talk “Your brain hallucinates your conscious reality”. In the beginning of May, he visits Lund University and Neuroscience Day to give this year's prestigious Segerfalk lecture. We meet on zoom for a conversation about AI, the mystery of consciousness and – of course – to find out what he knew about Sweden. … how would you explain consciousne

https://www.medicine.lu.se/article/hello-there-anil-seth - 2025-10-21

A Nobel laureate and a pioneer have been appointed honorary doctors 2023 at our faculty. On May 24, they offer their insights into the sensitivities of body and mind in an open lecture. In this lecture you will hear the 2023 honorary doctors of the Faculty of Medicine, Nobel laureate professor David Julius and professor Rita Charon each talk about their research and what it has taught them about t

https://www.medicine.lu.se/article/understanding-sensitivities-body-and-mind-open-lecture-2023-honorary-doctors-faculty-medicine - 2025-10-21

Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international symposium on drug research. Medications are the physician's primary tool when treating their patients, and understanding how drugs work is fundamental to being a good doctor, according to Lars Grundemar, adjunct professor of clin

https://www.medicine.lu.se/article/superstars-coming-lund-drug-and-pharmaceutical-symposium - 2025-10-21

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.medicine.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-10-21

What happens when you mix a group of tumor biology researchers with software developers and AI researchers? Hopefully, with the help of AI, they can connect a multitude of data that leads to new treatments for kidney cancer – that's at least what the researchers in the EU-project KATY envision. But first, they need to find a common language that all professional groups understand. – It's a challen

https://www.medicine.lu.se/article/kicking-kidney-cancer - 2025-10-21

Researchers led by Lund University in Sweden have assisted microbiologists in Ukraine in investigating bacterial resistance among the war-wounded patients treated in hospitals. The results, which were recently published in The Lancet Infectious Diseases, reveal that many of the patients were affected by bacteria that exhibited an extremely high level of antibiotic resistance. “I am quite thick-ski

https://www.medicine.lu.se/article/alarming-antibiotic-resistance-discovered-war-torn-ukraine - 2025-10-21

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. The studies are published in Nature Medicine, where the researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before ot

https://www.medicine.lu.se/article/lewy-body-disease-can-be-detected-symptoms - 2025-10-21

What is the link between atherosclerosis and gut and mouth bacteria? Researchers behind a large new study have found several new connections. In the long term, this knowledge can benefit people with type 2 diabetes, a group with an increased risk of developing atherosclerosis. In atherosclerosis, fat and calcium have accumulated in the artery walls over time, forming so called atherosclerotic plaq

https://www.medicine.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2025-10-21

Researchers at Lund and Gothenburg Universities have successfully developed temporary, organic electrodes that can be seamlessly integrated into biological systems. The method, now published in Nature Communications, opens up a future where bioelectronics can be implanted in and removed from the body without surgery. Electrotherapy is a medical treatment method that uses electrical currents to sti

https://www.medicine.lu.se/article/electrotherapy-without-surgery - 2025-10-21