Sökresultat

We are working in close collaboration with neuroscientists from the B.R.A.I.N.S unit at the Biomedical Center to develop techniques for 3D imaging of cleared mouse brain tissue. These techniques will assist their research on Parkinson’s and Alzheimer’s disease. Clearing of tissue have become increasingly popular within the neuroimaging community over the last decade, as it offers researchers the n

https://www.combustionphysics.lu.se/article/advanced-microscopy-imaging-whole-mouse-brains-3d - 2025-11-03

Our group works with medical laser diagnostics, specifically aimed at monitoring of oxygen in lungs using the GAs in Scattering Media Absorption Spectroscopy (GASMAS) technique. This has found successful application in the monitoring of the lung function for preterm infants, where careful monitoring of spatially distributed oxygen content can lead to optimal respiratory support and prompt detectio

https://www.combustionphysics.lu.se/article/monitoring-oxygen-lungs-using-light-amplification-suggested-thesis-project - 2025-11-03

Imagine you had to get surgery due to esophagus cancer. Initially, you seem to recover well, but suddenly you are rushed to emergency surgery. The wound has failed to heal and the inflammation has caused severe, life-threatening sepsis. What if this could have been prevented? What if your doctors could have seen the problem in the wound days before the severe problem occurred, and been able to fix

https://www.combustionphysics.lu.se/article/method-measuring-healing-after-surgery - 2025-11-03

How can we stop global warming? Simple: we need to stop burning fossil fuels. Unfortunately, it is difficult to replace fossil fuels in all parts of society. In this project, we develop laser techniques that can help us understand the how energy is produced when different things burn, which will help developing new, clean biofuels. There are some areas in society where burning things is the best/e

https://www.combustionphysics.lu.se/article/lasers-will-help-us-discover-fuels-tomorrow - 2025-11-03

Most milk powders you buy have been produced through spray drying. This means that the milk after some preprocessing is injected under high-pressure through a small hole into a warm room. Then almost instantly, the liquid evaporates leaving the powder. The final product now has a longer shelf life, lower transport weight and can be stored in room temperature. However it is a very energy consuming

https://www.combustionphysics.lu.se/article/improving-food-spray-drying-tetra-pak - 2025-11-03

Ever since it was invented in the 1960s, the laser has found new areas of use, and is today very useful in research, industry and society. In most laser applications, for example material processing, the laser can be placed very close to the area to be processed. However, there are many important application areas where this is problematic. For example, if you want to use the laser to study an are

https://www.combustionphysics.lu.se/article/backward-lasing-breakthrough-remote-sensing - 2025-11-03

Directed acyclic graphs (DAGs), a prominent tool for expressing assumptions in epidemiologic research, are most useful when the hypothetical data generating structure is correctly encoded. Understanding a study’s data generating structure and translating that data structure into a DAG can be challenging, but these skills are often glossed over in training. New publication in Epidemiology

https://www.lupop.lu.se/article/graphical-catalog-threats-validity-linking-social-science-epidemiology - 2025-11-03

Sonographers have reported a high occurrence of musculoskeletal pain for more than 25 years. Assessments of occupational risk factors have previously been based on cross-sectional surveys. The aim of this longitudinal study was to determine which factors at baseline that were associated with neck/shoulder and elbow/hand pain at follow-up. New publication in BMC Musculoskeletal Disorders

https://www.lupop.lu.se/article/neck-and-upper-extremity-pain-sonographers-longitudinal-study - 2025-11-03

In the 1980s debate intensified over whether there was a protective effect of high-density lipoprotein cholesterol (HDL-C) or an adverse effect of triglycerides on coronary heart disease (CHD) risk. In a 1991 paper reprinted in the IJE we suggested that the high degree of correlation between the two, together with plausible levels of measurement error, made it unlikely that conventional epidemiolo

https://www.lupop.lu.se/article/correlation-without-cause-epidemiological-odyssey - 2025-11-03

Duplicate and salami publication are unethical, but are common practices with substantial consequences for science and society at large. Scientific journals are the ‘gatekeepers’ of the publication process. We investigated journal policies on duplicate and salami publication New publicationin International Journal of Epidemiology

https://www.lupop.lu.se/article/duplicate-and-salami-publication-prevalence-study-journal-policies - 2025-11-03

Directed acyclic graphs (DAGs) are popular tools for identifying appropriate adjustment strategies for epidemiological analysis. However, a lack of direction on how to build them is problematic. As a solution, we propose using a combination of evidence synthesis strategies and causal inference principles to integrate the DAG-building exercise within the review stages of research projects. We demon

https://www.lupop.lu.se/article/evidence-synthesis-constructing-directed-acyclic-graphs-esc-dags-novel-and-systematic-method - 2025-11-03

Exposures to perfluoroalkyl substances (PFAS) have shown positive associations with serum lipids in previous studies. While many studies on lipids investigated associations with perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), there are only a few studies regarding other PFAS, such as perfluorohexane sulfonic acid (PFHxS). The purpose of the current study is to investigate i

https://www.lupop.lu.se/article/associations-between-perfluoroalkyl-substances-and-serum-lipids-swedish-adult-population - 2025-11-03

Partial exchangeability is sufficient for the identification of some causal effects of interest. Here we review the use of common graphical tools and the sufficient component cause model in the context of partial exchangeability. We illustrate the utility of single world intervention graphs (SWIGs) in depicting partial exchangeability and provide an illustrative example of when partial exchangeabi

https://www.lupop.lu.se/article/graphical-description-partial-exchangeability - 2025-11-03

For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregivers. The aim of this s

https://www.lupop.lu.se/article/analyzing-situation-older-family-caregivers-focus-health-related-quality-life-and-pain-cross - 2025-11-03

Analyses of causal mediation are often complicated by treatment-induced confounders of the mediator–outcome relationship. In the presence of such confounders, the natural direct and indirect effects of treatment on the outcome, into which the total effect can be additively decomposed, are not identified. An alternative but similar set of effects, known as randomized intervention analogues to the n

https://www.lupop.lu.se/article/effect-decomposition-presence-treatment-induced-confounding-regression-residuals-approach - 2025-11-03

Heparin is the preferred choice of anticoagulant in percutaneous coronary intervention (PCI) for acute myocardial infarction (MI). An established dosage of heparin has not yet been determined, but treatment may be optimized through monitoring of activated clotting time (ACT).. New publication in Europe PMC

https://www.lupop.lu.se/article/relationship-between-degree-heparin-anticoagulation-and-clinical-outcome-patients-receiving-potent - 2025-11-03

This issue of the Journal contains two articles focusing on how to draw causal conclusions using data from multiple studies that would generally be analyzed via meta-analysis. New publication in Epidemiology.

https://www.lupop.lu.se/article/importance-homogeneous-effect-modification-causal-interpretation-meta-analyses - 2025-11-03

In this population-based study, we compared the incidence of distal radius fracture in 2016 with that in the same region’s adult general population in 2001 using radiographs to identify fracture cases. We showed that the incidence decreased by 24% in 2016 compared with 2001 indicating an important development. New publication in Osteoporosis International

https://www.lupop.lu.se/article/incidence-distal-radius-fracture-general-population-southern-sweden-2016-compared-2001 - 2025-11-03

We recently suggested new statistical metrics for routine reporting in random-effects meta-analyses to convey evidence strength for scientifically meaningful effects under effect heterogeneity. First, given a chosen threshold of meaningful effect size, we suggested reporting the estimated proportion of true population effect sizes above this threshold. Second, we suggested reporting the proportion

https://www.lupop.lu.se/article/robust-metrics-and-sensitivity-analyses-meta-analyses-heterogeneous-effects - 2025-11-03

In this prospectively registered cohort study, we analyzed clinical, pathological, and survival outcomes for patients operated in the period 2008–2015 and compared the two strategies. New publication in World Journal of Surgery

https://www.lupop.lu.se/article/outcomes-simultaneous-resections-and-classical-strategy-synchronous-colorectal-liver-metastases - 2025-11-03