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A far-reaching Regulation for the Italian National Registry of Implantable Prostheses: a possible model for other health registries

Published 25 August 2021 Photo: Pixabay / Sasin Tipchai Our aim is to identify a few key issues to shape a far-reaching Regulation that might permit the flexible and dynamic functioning of RIPI (Regulation of the Italian Implantable Prostheses Registry) providing suggestions for other registries at national and international level. Read the paper at https://www.iss.it/documents/20126/0/ANN_21_02_0

https://www.lupop.lu.se/article/far-reaching-regulation-italian-national-registry-implantable-prostheses-possible-model-other-health - 2024-12-26

Different, yet strong together: the Nordic Arthroplasty Register Association (NARA)

Published 27 August 2021 Photo: Pixabay / Angelo Esslinger The Nordic Arthroplasty Register Association (NARA) was established in 2007 by hip and knee arthroplasty registry leaders from Denmark, Norway, and Sweden. Purportedly, the idea of combining national databases was presented and discussed while sitting in a bar. Read the editorial at https://www.tandfonline.com/doi/full/10.1080/17453674.202

https://www.lupop.lu.se/article/different-yet-strong-together-nordic-arthroplasty-register-association-nara - 2024-12-26

Study Designs for Extending Causal Inferences From a Randomized Trial to a Target Population

Published 27 August 2021 Photo: Pixabay / Gerd Altmann In this article, we examine study designs for extending (generalizing or transporting) causal inferences from a randomized trial to a target population. Specifically, we consider nested trial designs, where randomized individuals are nested within a sample from the target population, and nonnested trial designs, including composite data-set de

https://www.lupop.lu.se/article/study-designs-extending-causal-inferences-randomized-trial-target-population - 2024-12-26

Causal analyses of existing databases: no power calculations required

Published 1 September 2021 Photo: Pixabay / Gerd Altmann A key misunderstanding is the belief that the goal of a causal analysis is to “detect” an effect. Causal effects are not binary signals that are either detected or undetected; causal effects are numerical quantities that need to be estimated. Read the paper at https://www.sciencedirect.com/science/article/abs/pii/S0895435621002730

https://www.lupop.lu.se/article/causal-analyses-existing-databases-no-power-calculations-required - 2024-12-26

Agenda 2030: Postdoctoral researcher in Biodiversity and health

Published 1 September 2021 I ramverket kommer vi använda kunskap om biologisk mångfald, ekologiska processer, miljöpsykologi, och epidemiologi för att hitta en gemensam väg framåt för att bemöta dessa globala utmaningar i praktiken. Vi rekryterar nu tre postdoktorer som tillsammans kommer att koordinera forskningen i projektet. Läs mer och sök tjänsterna på https://lu.varbi.com/what:job/jobID:4224

https://www.lupop.lu.se/article/agenda-2030-postdoctoral-researcher-biodiversity-and-health - 2024-12-26

Big data registries in spine surgery research: the lurking dangers

Published 2 September 2021 Photo: Pixabay / Sasin Tipchai Spine surgery research has improved considerably over the last few decades. Its’ most recent growth is in large part due to the mounting increase in studies conducted using national databases and registries. With easy access to a large number of patients, the benefit of these registries has become evident. However, as with any research, thi

https://www.lupop.lu.se/article/big-data-registries-spine-surgery-research-lurking-dangers - 2024-12-26

Book review: Modern Epidemiology, 4th edition

Published 2 September 2021 Modern Epidemiology 4th is a gigantic project completed in grand style. One can only imagine all the considerations and discussions about content, terminology, ordering, et cetera that the authors had to go through and agree on to make this edition happen. Read the review at https://link.springer.com/article/10.1007%2Fs10654-021-00778-w

https://www.lupop.lu.se/article/book-review-modern-epidemiology-4th-edition - 2024-12-26

Available positions at the Department of Public Health, Aarhus University

Published 5 September 2021 Photo: Pixabay / geralt The Department of Public Health contributes to teaching in medicine, public health science, sport science and nursing. At the department, you will have approx. 200 colleagues, including 90 academic staff members and a corresponding number of PhD students. Available positions: Tenure Track Assistant Professor at the Department of Public Health Prof

https://www.lupop.lu.se/article/available-positions-department-public-health-aarhus-university - 2024-12-26

A Real-World Rheumatology Registry and Research Consortium: The German RheumaDatenRhePort (RHADAR) Registry

Published 7 September 2021 Photo: Pixabay / congerdesign The German RheumaDatenRhePort (RHADAR) registry encompasses a network of rheumatologists and researchers in Germany providing pseudonymized real-world patient data and allowing timely and continuous improvement in the care of RMD patients. Read the paper at https://www.jmir.org/2021/5/e28164

https://www.lupop.lu.se/article/real-world-rheumatology-registry-and-research-consortium-german-rheumadatenrheport-rhadar-registry - 2024-12-26

The role of kidney registries in expediting large-scale collection of patient-reported outcome measures for people with chronic kidney disease

Published 7 September 2021 Photo: Pixabay / www_slon_pics In this editorial, we discuss the current state-of-play of PROMs collection by kidney registries and provide an overview of what is (un)known about the feasibility and effectiveness of PROMs in CKD and other conditions. Read the paper at https://academic.oup.com/ckj/article/14/6/1495/6173985

https://www.lupop.lu.se/article/role-kidney-registries-expediting-large-scale-collection-patient-reported-outcome-measures-people - 2024-12-26

SWEDEGENE—a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions

Published 8 September 2021 Photo: Pixabay / Arek Socha SWEDEGENE was established in 2008 and currently contains DNA and information from about 2550 adults who have experienced specific ADRs, and from 580 drug exposed controls. Read the paper at https://www.nature.com/articles/s41397-020-0148-3

https://www.lupop.lu.se/article/swedegene-swedish-nation-wide-dna-sample-collection-pharmacogenomic-studies-serious-adverse-drug - 2024-12-26

Bias Analysis Gone Bad

Published 8 September 2021 We identified 3 examples of suboptimal bias analysis, one for each common bias. For each, we describe the original research and its bias analysis, compare the bias analysis with good practices, and describe how the bias analysis and research findings might have been improved. Read the paper at https://academic.oup.com/aje/article/190/8/1604/6189735

https://www.lupop.lu.se/article/bias-analysis-gone-bad - 2024-12-26

Emulating Target Trials to Improve Causal Inference From Agent-Based Models

Published 9 September 2021 Photo: Pixabay / Gerd Altmann In this paper, we describe the use of the target trial framework for designing agent-based models when the goal is estimation of causal effects in the presence of interference, or spillover. Read the paper at https://academic.oup.com/aje/article/190/8/1652/6140873

https://www.lupop.lu.se/article/emulating-target-trials-improve-causal-inference-agent-based-models - 2024-12-26

European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria

Published 9 September 2021 Photo: Pixabay / Arek Socha This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. Read the paper at https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019…

https://www.lupop.lu.se/article/european-registry-type-aortic-dissection-ertaad-rationale-design-and-definition-criteria - 2024-12-26

Propensity Score Weighting and Trimming Strategies for Reducing Variance and Bias of Treatment Effect Estimates: A Simulation Study

Published 10 September 2021 To extend previous simulations on the performance of propensity score (PS) weighting and trimming methods to settings without and with unmeasured confounding, Poisson outcomes, and various strengths of treatment prediction (PS c statistic), we simulated studies with a binary intended treatment T as a function of 4 measured covariates. Read the paper at https://academic.

https://www.lupop.lu.se/article/propensity-score-weighting-and-trimming-strategies-reducing-variance-and-bias-treatment-effect - 2024-12-26

Data from national health registers as endpoints for the Tromsø Study: Correctness and completeness of stroke diagnoses

Published 11 September 2021 Photo: Pixabay / VSRao The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14034948211021191

https://www.lupop.lu.se/article/data-national-health-registers-endpoints-tromso-study-correctness-and-completeness-stroke-diagnoses - 2024-12-26

A cautionary note on a recently proposed sensitivity analysis for unmeasured confounding

Published 11 September 2021 Unmeasured confounding is a common threat to the validity of observational studies. In practice, confounding bias may arise from both confounders that are completely unmeasured and from confounders that are measured with error. Read the paper at https://academic.oup.com/ije/article/50/3/711/6048186

https://www.lupop.lu.se/article/cautionary-note-recently-proposed-sensitivity-analysis-unmeasured-confounding - 2024-12-26