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Enormous amounts of data about Alzheimer’s Disease have been generated from clinical studies so far. Still, the molecular drivers of Alzheimer’s Disease are largely unknown. With the TAU-TIME project, Jacob Vogel aims to advance knowledge by developing an AI tool that brings together known biological mechanisms with data from patients with the disease. Recent funding from the European Research Cou

https://www.multipark.lu.se/article/time-unite-lab-and-clinic-15-million-eu-build-ai-model-alzheimers-disease - 2025-09-29

Early diagnosis is key to receiving proper care and advancing research on future therapies for neurodegenerative diseases such as Parkinson’s and dementia with Lewy bodies. New research from Skåne University Hospital and Lund University shows that combining a simple smell test with advanced spinal fluid analysis can predict these diseases with high accuracy, while sparing nearly half of patients f

https://www.multipark.lu.se/article/smell-test-cuts-need-invasive-parkinsons-screening - 2025-09-29

Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer's disease that is intended for use in primary care. “This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician's ability to determine who should be further examined by blood tests for Alzheimer's pathology ear

https://www.multipark.lu.se/article/new-digital-cognitive-test-diagnosing-alzheimers-disease - 2025-09-29

What if brain diseases could be cured by turning on the proper genes? Meet our scientist, Professor Cecilia Lundberg! She explains how gene therapy may complement cell therapies to combat Parkinson’s disease. Cecilia Lundberg is head of the CNS Gene Therapy Research Group and has spent her whole career developing cutting-edge tools that may be used in future therapies to slow down or cure neurodeg

https://www.multipark.lu.se/article/meet-our-scientists-podcast-cecilia-lundberg-about-gene-workshop - 2025-09-29

How do you stop Alzheimer’s disease without a simple way to diagnose it? It’s a real chicken and egg problem, as I wrote last year on TGN. Discovering a treatment for Alzheimer’s requires lots of clinical trials for new drugs—but it’s difficult to enroll participants without a way to identify people who have the disease early enough for potential treatments to work. Read the full article here

https://www.multipark.lu.se/article/unexpected-way-we-might-one-day-diagnose-alzheimers - 2025-09-29

A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. The researchers analysed neurofilament light protein (NFL) in blood samples from patients with Alzheimer’s disease. Recently published in JAMA Neurology, the study suggests that the NFL concentration in the blood could be able to indicate if a drug actually affects the loss of ner

https://www.multipark.lu.se/article/more-evidence-blood-tests-can-detect-risk-alzheimers - 2025-09-29

In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study led by researchers at Lund University in Sweden now shows the de facto key role played by the protein in Alzheimer’s disease. When the researchers shut off the gene that produces this protein in mice, the amount of Alzheimer’s plaque and the inflam

https://www.multipark.lu.se/article/researchers-block-protein-plays-key-role-alzheimers-disease - 2025-09-29

Daniella was awarded the prize for "successful effort as a young researcher and group leader". Link to Jeanssons Foundation website (in Swedish)

https://www.multipark.lu.se/article/daniella-ottosson-receives-prize-jeanssons-foundation - 2025-09-29

The Future Faculty is proud to present the 2019 Minerva Award to Tomas Deierborg, associate professor at the Department of Experimental Medical Sciences.The Minerva award selection committee's motivation for the choice is: "The core values of the Minerva award are honesty, trust, fairness, respect, responsibility and courage. From the nominations it is obvious that Tomas Deierborg possess all thes

https://www.multipark.lu.se/article/minerva-award-tomas-deierborg - 2025-09-29

In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces. Roche Diagnostic’s Elecsys system predicted Aβ-positive individuals with about 80 percent accuracy. That number improved by 5 percent when the researchers took ApoE genotype into consideration. Alzforum first repo

https://www.multipark.lu.se/article/drawing-closer-alzheimers-blood-test-primary-care - 2025-09-29

Scientists are becoming more nuanced in how they use amyloid scans—not just to detect the presence of Alzheimer’s pathology, but also to pinpoint disease stage. At this year’s Alzheimer’s Association International Conference, held July 13–18 in Los Angeles, researchers led by Niklas Mattsson and Oskar Hansson at Lund University, Sweden, debuted a new staging scheme. Read the full article here

https://www.multipark.lu.se/article/new-pet-staging-scheme-amyloid - 2025-09-29

On October 30, MultiPark arranged, in collaboration with the Parkinson Skåne patient organization and Studieförbundet Vuxenskolan, a half-day study visit for the public to the Biomedical Center. Professor Angela Cenci Nilsson led the event and guided the audience through the afternoon.       The chair of Parkinson Skåne gave a brief presentation of their organization, followed by talks by two pers

https://www.multipark.lu.se/article/parkinson-skane-visits-bmc - 2025-09-29

Oskar Hansson, professor of neurology at Lund University and cheif physician at Skåne University Hospital, is included in this year´s list of highly cited researchers that Web of Science compiles each year.Read the article (in Swedish) on the Faculty of Medicine website.

https://www.multipark.lu.se/article/congratulations-oskar-hansson-list-highly-cited-2019 - 2025-09-29

Half as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 with a matched cohort of the general population. The results of the population reg

https://www.multipark.lu.se/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimers - 2025-09-29

Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.Read the full article here

https://www.multipark.lu.se/article/high-tech-method-uniquely-targeted-gene-therapy-developed - 2025-09-29

Diagnosing Alzheimer's disease is often difficult, as several other conditions can cause similar symptoms. Researchers at Lund University in Sweden have now discovered a blood marker that can accurately diagnose Alzheimer’s in the early stages of the disease.Read the full article here

https://www.multipark.lu.se/article/blood-test-enables-early-diagnosis-alzheimers-disease - 2025-09-29

To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal Advanced Science.Read the full article here

https://www.multipark.lu.se/article/new-imaging-method-sheds-light-alzheimers-disease - 2025-09-29

Hela Sverige riskerar att få en liknande situation som den på Stockholms äldreboenden om vi inte gör mer för att minska spridningen av viruset på boendena. Det skriver flera debattörer, som lägger fram fem förslag.Länk till artikel

https://www.multipark.lu.se/article/detta-bor-goras-att-skydda-aldre-pa-boenden - 2025-09-29

Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the treatment of neurologica

https://www.multipark.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-09-29

Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.Read the full article here

https://www.multipark.lu.se/article/how-toxic-protein-spreads-alzheimers-disease - 2025-09-29