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High Physical Activity Level and the Long-Term Risk of Atrial Fibrillation in Two Swedish Cohorts

Background: Associations between high physical activity (PA) levels and incident atrial fibrillation (AF) is found in some earlier studies. We aim to study the association between levels of PA and AF in two cohorts. Methods: We used data from the Uppsala Longitudinal Study of Adult Men (ULSAM) study, initiated in 1970, included men aged 50 years, with 2202 included in the study. Examinations were

Emergence and Global Spread of Mpox Clade Ib : Challenges and the Role of Wastewater and Environmental Surveillance

Several African countries, mainly the Democratic Republic of Congo, Burundi, and Uganda, are facing highly transmissible mpox clade Ib epidemics, prompting the World Health Organization to declare a Public Health Emergency of International Concern. It has spread to key travel hubs like Kinshasa, Bujumbura, and Kampala, increasing international spread risks. Current mitigation efforts focus mainly

Quantification of Lewy body pathology by cerebrospinal fluid endpoint dilution RT-QuIC in a neuropathological autopsy cohort of clinically heterogeneous participants

The identification of biomarkers predicting the burden of brain alpha-synuclein (α-syn) pathology in vivo represents a research priority in Lewy body disease (LBD). Recently, some kinetic parameters of seed amplification assays (SAAs) for α-syn showed associations with measures of clinical progression. However, preanalytical and analytical factors significantly affect these parameters, reducing re

The 2024 Roxborough Park Wildfire Evacuation Drill - Lessons learned after planning, running, and studying a community evacuation exercise

In June 2024, the community of Roxborough Park, Colorado conducted a wildfire evacuation exercise (or drill for short) that was observed by a team of researchers. This collaborative effort involved residents, community organizers, first responders, emergency managers, and researchers. The drill aimed to test and refine evacuation protocols, communication strategies, and coordination among various

A unique Permian-Triassic boundary section from the Neotethyan Hawasina Basin, Central Oman Mountains

In the Wadi Wasit area (Central Oman Mountains), Dienerian breccias are widespread. These breccias consist mostly of Guadalupian reefal blocks, often dolomitised, and some rare small-sized blocks of lowermost Triassic bivalve-bearing limestones, A unique block, with a size of about 200 m3, including Permian and earliest Triassic faunas has been studied in detail. The so-called Wadi Wasit block con

Follow-Up Magnetic Resonance Imaging in Monitoring Charcot Foot and Its Association With Total Contact Cast Treatment Duration and Long-Term Outcomes : A Retrospective Cohort Study

Aims/Hypothesis: Charcot foot (CF), a potentially debilitating complication of neuropathy, requires offloading to avoid foot deformities. Follow-up MRI examinations are often used to determine the optimal duration of total contact cast (TCC) offloading treatment. This study investigated the use of follow-up MRI during CF treatment and its relationship to offloading duration and risk of future surg

Determining Pilot Ignition Delay in Dual-Fuel Medium-Speed Marine Engines Using Methanol or Hydrogen

Dual-fuel engines are a way of transitioning the marine sector to carbon-neutral fuels like hydrogen and methanol. For the development of these engines, accurate simulation of the combustion process is needed, for which calculating the pilot’s ignition delay is essential. The present work investigates novel methodologies for calculating this. This involves the use of chemical kinetic schemes to co

Phylogeny and genetic variation in the genus Eranthis using nrITS and cpIS single nucleotide polymorphisms

The relationships among species in the genus Eranthis Salisb. were investigated using single nucleotide polymorphisms (SNPs) of the nuclear DNA internal transcribed spacer 1, 2 region (nrITS) and the chloroplast trnL-trnF interspacer region (cpIS). Phylogenetic relationships based on the nrITS and cpIS were inferred with posterior probabilities with STRUCTURE analysis and the neighbor-joining meth

Summary of Early Triassic carbon isotope records

Much attention has been given to the negative δ13C anomaly nearly coincident with the Permian-Triassic boundary. New data indicate a stepwise decline in δ13C initiating before the Latest Permian extinction event followed by highly variable δ13C values during the remaining Early Triassic. δ13C values appear much less erratic as global metazoan diversity increased in the Middle Triassic. Given the p

Solving Nonlinear PDEs Using CUDA

Partial differential equations (PDEs) are central in many scientific research areas, including modeling physical phenomena and economic forecasting. While the general solutions of PDEs can be complex, we can determine a particular solution by introducing boundary conditions and/or initial conditions. This is called an Initial Boundary Value Problem (IBVP). Thalassa is a framework that generates s

Rapid marine recovery after the end-Permian mass-extinction event in the absence of marine anoxia

A new Early Triassic marine fauna is described from the Central Oman Mountains. The fauna is Griesbachian in age, on the basis of abundant conodonts and ammonoids, and was deposited in an oxygenated seamount setting off the Arabian platform margin. It is the first Griesbachian assemblage from a well-oxygenated marine setting and thus provides a test for the hypothesis that widespread anoxia preven

Begonia limprichtii Irmsch. (Begoniaceae) – a new record for India

Begonia limprichtii (Begoniaceae) is reported from India for the first time. It belongs to the section Platycentrumand is similar to B. thomsonii, but is overall less hairy with ovary nearly glabrous (versus villous) and upper ovary wing beaked and rounded (versus triangular).

Environmentally sustainable diets and human health - Nutritional adequacy, disease risk, and mortality

Introduction: Food systems strongly influence both human and planetary health. Unhealthy diets aremajor risk factors for chronic disease and mortality, while food production contributes substantially togreenhouse gas emissions (GHGE), and other negative environmental impacts. Adopting moresustainable dietary patterns, such as the EAT-Lancet diet, has been proposed as part of the solution, butuncer

Through the bubble : universal design and equitable pelvic floor care

Förlossningen är en omvälvande och minnesvärd livshändelse. Den nyblivnamammans fokus ligger på det nyfödda barnet, likaså vårdpersonalens. Enförlossning kan leda till allvarliga skador på bäckenbotten (pelvic floor, PF),ibland med komplikationer som inkontinens. Tyvärr förbises eller tonas dessaskador ofta ned – både av nyblivna mödrar och vårdgivare. I Sverige drabbasungefär 1–4% av kvinnor som Giving birth is a profound life event. Most of the time, mothers move their attention to their newborn, as do healthcare providers. Childbirth can cause severe pelvic floor (PF) injuries, potentially leading to complications, such as incontinence. Despite their impact, these injuries are often deprioritised or normalised—both by postpartum women and healthcare providers. In Sweden, 1–4% of women w

Inter- and Intramolecular On-Surface Synthesis of Porphyrin-Based Nanostructures on Au(111) and Cu(111)

Surface-confined synthesis provides alternative reaction pathways to those utilized within solution-phase chemistry and offers a route to extended molecular architectures with nanoscale dimensions and fascinating magnetic, electronic, and catalytic properties. However, these reaction pathways can be complex multistep processes, containing multiple reactive intermediates. Optimizing the selectivity

Predictability-Aware Motion Prediction for Edge XR via High-Order Error-State Kalman Filtering

As 6G networks evolve, offloading extended reality (XR) applications emerges as a key use case, leveraging reduced latency and edge processing to migrate computationally intensive tasks, such as rendering, from user devices to the network. This enables lower battery consumption and smaller device form factors in cellular environments.However, offloading incurs delays from network transmission and

Reflex-plan : a safety monitoring architecture for thinking fast and slow

Ensuring functional safety is crucial for the deployment of autonomous systems in real-life dynamic environments, as they must operate reliably and safely among humans. However, existing safety systems are designed with a closed-world assumption and can over-constrain the system by shutting down the robot at every safety violation, limiting the robot’s ability to complete its tasks. To address thi