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A combination of searches for the single production of vectorlike top quarks ((Formula presented)) is presented. These analyses are based on proton-proton collisions at (Formula presented) recorded in 2015-2018 with the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of (Formula presented). The (Formula presented) decay modes considered in this combination ar

Trauma-induced hemorrhagic shock (HS) plays a decisive role in the development of immune, coagulation, and organ dysfunction often resulting in a poor clinical outcome. Imbalanced complement activation is intricately associated with the molecular danger response and organ damage after HS. Thus, inhibition of the central complement component C3 as turnstile of both inflammation and coagulation is h

Increasing evidence indicates an integral role for the complement system in the deleterious inflammatory reactions that occur during critical phases of the transplantation process, such as brain or cardiac death of the donor, surgical trauma, organ preservation and ischaemia-reperfusion injury, as well as in humoral and cellular immune responses to the allograft. Ischaemia is the most common cause

We describe the presumably first intentional ABO-incompatible deceased-donor kidney and pancreas transplantation with a severe antibody-mediated rejection during a rebound of isoagglutinins. Rejection was successfully treated with eculizumab, which inhibits the terminal pathway of complement. Complement analysis (C3, C3d,g, and a modified assay of classical complement-related hemolytic function) d

A reliable serological marker of acute cellular rejection (ACR) after small bowel transplantation (SBTx) is still missing. Plasma citrulline level (PCL) reflects the functional integrity of intestinal mucosa which is partially lost during ACR. The aim of our study was to investigate the role of PCL as marker of ACR after SBTx. Eighteen German landrace pigs were used and divided into three groups.

High blood pressure (BP) is a frequent cause for visits to primary healthcare centers (PHCCs) in Sweden. Guidelines on methods for BP measurements for diagnosis of hypertension have recently been updated. We aimed to study adherence to diagnostic guidelines in hypertension management and evaluate whether adherence to guidelines was related to organizational or sociodemographic characteristics. Int

In this bachelor thesis, I examine how professional translators handle the Danish discourse particles da, nok, and sgu in translations of Danish fiction texts into Swedish. Of particular interest is how the omission of these discourse particles affects the stylistic character of the text and what implications this has for the reader's experience of the target text. My corpus consists of four D

Linguistic development is an inherent and dynamic characteristic of all living languages, whereby new words and expressions emerge in response to societal changes, while existing lexical elements either disappear or shift in meaning. A significant driving force in this process is lexical borrowing, which serves to fill lexical gaps when the target language lacks terms for new concepts. This th

This thesis investigates the lived experiences of women with Attention Deficit Hyperactivity Disorder (ADHD), diagnosed in adulthood in Denmark, focusing on how culturally ingrained norms and diagnostic frameworks contribute to masking behaviours, delayed recognition and systemic exclusion. The reason behind this thesis is a persistent underdiagnosis of ADHD in women and the subsequent resultant n

A year after the establishment of the protest camp Palestinagård at Lund’s University in May 2024 and its demolishment by the authorities, the student solidarity movement is continuously engaged in endeavours to get into conversations with the institutions at Lunds University to make their demands heard, as the genocide on the Palestinian population in Gaza is still ongoing. Further, Palestinagård

There is a growing awareness that complement plays an integral role in human physiology and disease, transcending its traditional perception as an accessory system for pathogen clearance and opsonic cell killing. As the list of pathologies linked to dysregulated complement activation grows longer, it has become clear that targeted modulation of this innate immune system opens new windows of therap

BACKGROUND: Survivin regulates cell division and inhibits apoptosis. Liver regeneration is a complex process involving both proliferation and apoptosis. The role of survivin is not well elucidated and no data exist in humans.METHODS: Seventy per cent liver resection was used to investigate liver regeneration in rats. Survivin was identified by means of reverse transcriptase polymerase chain reacti

BACKGROUND: The aim of the study was to determine the role of Vascular Endothelial Growth Factor (VEGF) on the microvasculature and on angiogenetic gene expression after partial hepatectomy (PH) in the rat model.METHODS: To determine the effect of exogenous and endogenous VEGF after PH, rats were subjected to 70% PH and treated either with VEGF, anti-VEGF or NaCl. Postoperatively (3-168 h), vessel

BACKGROUND AND AIM: Hepatorenal syndrome (HRS) occurs in about 20 % of patients with liver cirrhosis and ascites and is characterized by intensive renal vasoconstriction, low glomerular filtration rate but preserved tubular function and normal renal histology. The potential of terlipressin and albumin to reverse HRS after a time period of 14 days has already been shown. However, intravenous albumi

The central component of the complement cascade, C3, is involved in various biological functions, including opsonization of foreign bodies, clearance of waste material, activation of immune cells, and triggering of pathways controlling development. Given its broad role in immune responses, particularly in phagocytosis and the clearance of microbes, a deficiency in complement C3 in humans is often

The humoral barrier in transplant biology is the result of preformed donor-specific antibodies (DSAs), directed either against human leukocyte antigens (HLA) or non-HLA antigens such as blood group (ABO) molecules. The term "sensitization" applies to patients carrying these antibodies. Transplantation is widely accepted as a life-saving opportunity for patients with terminal end-organ disease. How