The medial temporal lobe in aging and Alzheimer’s disease: A deep dive into anatomy, methodology, and clinical characterization
Alzheimer’s disease, the most common form of dementia, is characterized by progressive cognitive decline and the accumulation of amyloid-beta (Aβ) and tau neurofibrillary tangle (NFT) pathology. The medial temporal lobe (MTL) is one of the earliest sites of NFT pathology, crucial for memory functioning, and is made up of cytoarchitectonic and functionally different subregions. These subregions are
