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Traumatic brain injury (TBI) is the leading cause of death among the young, and has an increasing incidence among the elderly. In Sweden there are 20 000 new TBI cases each year, of which most are mild. The primary impact can lead to different types of brain hemorrhages, fractures and diffuse axonal injuries. The level of consciousness is used to define injury severity. Of all TBIs, 4-5 percent re
Statistics from the Swedish Social Insurance Agency show a sharp increase in the number of sick leave cases with the diagnoses Concussion, S06.0, and Postconcussional syndrome, F07.2, between the years 2010 and 2022. The reason for the increase has not been established and needs further investigation. One possible reason is that the acute phase treatment recommendations of individuals with mild tr
Lake water storage variations on the Tibetan Plateau (TP) serve as crucial indicators of regional hydrological dynamics and climate changes, providing more comprehensive insights than discrete measurements of lake area or water level alone. While accurate bathymetric data is fundamental for quantifying lake water storage, conventional bathymetric surveys are often constrained by logistical challen
Daniel Suhonen och Tony Johansson från den fackliga tankesmedjan Katalys vill i Di Debatt 8 december dölja det uppenbara: efterkrigstidens socialdemokratiska regleringar av den svenska kapitalmarknaden höll tillbaka svensk tillväxt i ett halvt sekel, skriver Lars Jonung. professor emeritus, Lunds universitet.
This book comprehensively explores various methodologies and sources used to understand and improve road safety. It delves into the advantages and disadvantages of primary data sources such as police accident records, statistical methods for data analysis, in-depth investigations, healthcare data, self-reporting of behavior, data from automated vehicles, naturalistic driving/cycling/walking studie
Enabling journeys from door-to-door is an essential part of attracting people towards public transport and away from the private car. Facilitating such journeys requires comprehensive and integrated planning across modal and spatial boundaries. Public transport governance, however, is often constrained by fragmented, multi-level structures and regulatory barriers that limit the ability of responsi
Immune checkpoint blockade (ICB) therapy can restore T cell function in tumors, but not all patients benefit, and the mechanisms behind this remain unclear. In this study, we used patient-derived organotypic (PDO) cultures from metastatic melanoma to examine transcriptomic and cellular changes following ex vivo T cell stimulation. Genomic and transcriptomic features were preserved during PDO forma
Lars Marcus’s book Städernas stenar (The stones of cities) presentsbasic concepts and the latest directions in the space syntax researcharea. Marcus’s presentation is based on the necessity of understandingthat urban planning as an area of knowledge is comprised of the materialreality of both the city and the “lived city”, human beings, and their useof the city as a tool, of being comprehended as
AbstractAim: This study sought to investigate the hypothesis that children dying outside a pediatric intensive care unit (PICU) after PICU discharge have a limitation of medical treatment (LOMT) order in place, limiting PICU readmission at the time of death.Methods: A cohort was identified of all children (n=3890; 5019 admissions) treated in a PICU in Sweden over 3 consecutive years between Januar
BACKGROUND: Head impacts are common in contact sports such as boxing and occur at times of elevated core body and brain temperatures induced by the exercise. Following impact, elevated brain temperature may lead to the development of exacerbated brain injury that can be monitored by blood biomarkers. Blood-brain biomarkers S100B and glial fibrillary acidic protein (GFAP) reflect glial injury; neur
We consider the verification of neural network policies for discrete-time stochastic systems with respect to reach-avoid specifications. We use a learner-verifier procedure that learns a certificate for the specification, represented as a neural network. Verifying that this neural network certificate is a so-called reach-avoid supermartingale (RASM) proves the satisfaction of a reach-avoid specifi
The aim of this study is to explore the internal damage mechanisms of AlSi12 metal matrix syntactic foam (MMSF) with embedded ceramic hollow spheres (CHSs) to understand the damage behavior during compressive loading. To achieve this goal, in situ synchrotron X-ray tomography is used. A qualitative and quantitative assessment of the initiation and gradual collapse of matrix, filler material, and p
Early recognition and management of sports-related concussion (SRC), including removal from the sports activity, is essential for player safety and to prevent long-term symptoms. A graduated, stepwise rehabilitation protocol is implemented to allow the athlete to return to sports. In 2022, the 6th international consensus statement on concussion in sports was presented, which has now been adapted t
Background and purpose — Musculoskeletal deformities in cerebral palsy (CP) may be surgically treated, but population-based studies of postoperative complications after these surgeries are rare. The aim of our study was to assess the risk of complications following elective orthopedic surgery in children and young adults with CP. Methods — We performed a register-based cohort study of 1,514 indivi
This paper integrates the concepts of first and second stories as well as Symbolic Interactionism and provides a framework that emphasizes the local rationality of practitioners and the social construction of meaning within their organizations. This paper will first consider some of the assumptions that characterize today’s safety discourse(s) because they inform how CS works with clients. What Sy
Artikel om de utrikespolitiska förbindelserna mellan Sverige och USA från ett jubileum 1938 (New Sweden Tercentenary Celebration) till ett annat 1948 (Swedish Pioneer Centennial).
Depression is a debilitating psychiatric disorder. Electroconvulsive therapy (ECT) and ketamine are effective treatments for severe depression, but target populations may differ. Systematic reviews on the few available trials show higher remission rates with ECT than with ketamine. Nonetheless, ketamine’s rapid onset of action is comparable to ECT but with less cognitive adverse effects. This make
The Polarization and Impedance Controlled Car (PICC) presents an innovative approach for demonstrating and teaching key principles of electromagnetic field theory, specifically polarization and impedance. Designed as an interactive learning tool, the PICC utilizes a radio-controlled car, NanoVNA, Raspberry Pi, and handheld antennas to visualize real-time effects of polarization and impedance. The
This invention relates to methods for purification of paclitaxel from a paclitaxel-containing material. The method comprises the following steps: (a) extracting a paclitaxel-containing material with an organic solvent to obtain an extract, and concentrating the extract; (b) adding the concentrate with an organic solvent which is not mixed with water to separate an organic solvent phase and then co
Micro-LEDs have emerged as a hot research topic due to their potential for next-generation display and lighting applications, necessitating advanced characterization techniques to optimize their performance. This study demonstrates the advantage of cathodoluminescence in the scanning electron microscope to be a critical tool for the optical characterization of InGaN platelets with red quantum well
