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Detection of lymph node metastases in patients with prostate cancer : Comparing conventional and digital [18F]-fluorocholine PET-CT using histopathology as a reference

Background: Positron emission tomography-computed tomography (PET-CT) with [18F]-fluorocholine (FCH) is used to detect and stage metastatic lymph nodes in patients with prostate cancer. Improvements to hardware and software have recently been made. We compared the capability of detecting regional lymph node metastases using conventional and digital silicon photomultiplier (SiPM)-based PET-CT techn

Patient trajectories after diagnosis of diffuse large B-cell lymphoma—a multistate modelling approach to estimate the chance of lasting remission

Background: Achieving lasting remission for at least 2 years is a good indicator for favourable prognosis long term after Diffuse large B-cell lymphoma (DLBCL). The aim of this study was to provide real-world probabilities, useful in risk communication and clinical decision-making, of the chance for lasting remissions by clinical characteristics. Methods: DLBCL patients in remission after primary

International experience makes a difference: Effects of studying abroad on students' self-efficacy

The present study examined whether students experience an increase in their general perceived self-efficacythrough international academic mobility. Two hundred and twenty-one students at Leuphana UniversityLüneburg were enrolled in a test-retest study with two points of measurement including a time interval of ap-proximately six months. Perceived self-efficacy was measured in a group of sojourners

International sojourn experience and personality development: Selection and socialization effects of studying abroad and the Big Five

As part of a multi-study project, this test-retest study seeks to identify the relations between studying abroad anda sojourner's personality as measured by the Big Five personality traits. It thereby attempts to answer the ques-tions of who chooses to study abroad and how study abroad changes personality. A total of 221 students from aGermanuniversity weretracked over the courseofa semester, with

Return to Sports : A Risky Business? A Systematic Review with Meta-Analysis of Risk Factors for Graft Rupture Following ACL Reconstruction

Background: The risk of sustaining a graft rupture after anterior cruciate ligament reconstruction (ACLR) is high. Contributing risk factors are, however, still not clearly identified. Objective: The aim of this systematic review was to identify and quantify risk factors for graft rupture after ACLR. Methods: A systematic review with meta-analysis (PROSPERO CRD42020140129) based on PRISMA guidelin

The Lund Molecular Taxonomy Applied to Non-Muscle-Invasive Urothelial Carcinoma

The precise classification of tumors into relevant molecular subtypes will facilitate both future research and optimal treatment. Here, the Lund Taxonomy system for molecular classification of urothelial carcinoma was applied to two large and independent cohorts of non-muscle-invasive tumors. Of 752 tumors classified, close to 100% were of the luminal subtypes, 95% urothelial-like (Uro; UroA, UroB

Medium development and production of carotenoids and exopolysaccharides by the extremophile Rhodothermus marinus DSM16675 in glucose-based defined media

Background: The marine thermophilic bacterium Rhodothermus marinus can degrade many polysaccharides which makes it interesting as a future cell factory. Progress using this bacterium has, however, been hampered by limited knowledge on media and conditions for biomass production, often resulting in low cell yields and low productivity, highlighting the need to develop conditions that allow studie

A novel membraneless β-glucan/O2 enzymatic fuel cell based on β-glucosidase (RmBgl3B)/pyranose dehydrogenase (AmPDH) co-immobilized onto buckypaper electrode

A novel membraneless β-glucan/O2 enzymatic fuel cell was developed by combining a bioanode based on buckypaper modified with co-immobilized Agaricus meleagris pyranose dehydrogenase (AmPDH) and Rhodothermus marinus β-glucosidase (RmBgl3B) (RmBgl3B-AmPDH/buckypaper) with a biocathode based on solid graphite modified with Myrothecium verrucaria bilirubin oxidase (MvBOx/graphite). AmPDH was connected

Massive star cluster formation and evolution in tidal dwarf galaxies

Context. The formation of globular clusters remains an open debate. Dwarf starburst galaxies are efficient at forming young massive clusters with similar masses as globular clusters and may hold the key to understanding their formation. Aims. We study star cluster formation in a tidal debris, including the vicinity of three tidal dwarf galaxies, in a massive gas-dominated collisional ring around N

Collider signatures of vector-like fermions from a flavor symmetric model

We propose a model with two Higgs doublets and several SU(2) scalar singlets with a global non-Abelian flavor symmetry Q6× Z2. This discrete group accounts for the observed pattern of fermion masses and mixing angles after spontaneous symmetry breaking. In this scenario only the third generation of fermions get their masses as in the Standard Model (SM). The masses of the remaining fermions are ge

Massive star cluster formation and evolution in tidal dwarf galaxies

The formation of globular clusters remains an open debate. Dwarf starburst galaxies are efficient at forming young massiveclusters with similar masses as globular clusters and may hold the key to understanding their formation.Aims.We study star cluster formation in a tidal debris - including the vicinity of three tidal dwarf galaxies - in a massive gas dominatedcollisional ring around NGC 5291. Th

Graphene: Applications in Surface Science Studies

This thesis addresses how graphene can be a valuable asset for surface science studies. Using a combination of X- ray photoelectron spectroscopy, scanning tunneling microscopy, and low-energy electron diffraction, we take advantage of graphene’s sensitivity to changes in its chemical environment to obtain an atomic scale understanding of different reactions occurring above and below the film.As a

Non-Standard Employment and Unemployment during the COVID-19 Crisis : Economic and Health Findings from a Six-Country Survey Study

The COVID-19 crisis is a global event that has created and amplified social inequalities, including an already existing and steadily increasing problem of employment and income insecurity and erosion of workplace rights, affecting workers globally. The aim of this exploratory study was to review employment-related determinants of health and health protection during the pandemic, or more specifical

Thriving or surviving? How the physical work setting at home was experienced globally during COVID-19

One of the most prominent and widely adopted COVID-19 countermeasures globally was the recommendation to work from home for all non-essential workers. Working from home (WFH) already entails many challenges, including difficulties in maintaining a healthy work-life balance. Moreover, the COVID-19 enforced remote working differed from planned remote work, as it was unplanned and involuntary, not ba

The Gaia-ESO Survey : Oxygen Abundance in the Galactic Thin and Thick Disks

We analyze the oxygen abundances of a stellar sample representative of the two major Galactic populations: the thin and thick disks. The aim is to investigate the differences between members of the Galactic disks and contribute to the understanding of the origin of oxygen chemical enrichment in the Galaxy. The analysis is based on the [O i] = 6300.30 Å oxygen line in high-resolution spectra (R ∼ 5

The right people, spaces and content for an inclusive hybrid community

The COVID-19 accelerated shift towards hybrid workspaces places major pressure onworkplace communities and culture. This study explores the emergence of a collaborative academic workspace, which is still in the real estate development phase. The aim is to establish preconditions for community building, and the relationship between the community and the physical space. The study employs a qualitati