Purpose: We aimed at analysing the risk of congestive heart failure (CHF) among first- and second-generation immigrants in younger age groups. Methods: All individuals aged 18–54 years, n = 3 973 454 in the first-generation study and n = 3 817 560 in the second-generation study, were included. CHF was defined as at least one registered diagnosis in the National Patient Register between 1 January 1

Purpose: Some patients with anterior cruciate ligament (ACL) injury initially treated with rehabilitation need ACL reconstruction (ACLR); yet, it is unclear what characterizes these patients. This review aimed to describe predictors for ACLR in patients initially treated with rehabilitation. Methods: A systematic literature search was performed in the Cochrane, Embase, Medline, SportsDiscus and We

District heating and cooling systems can aid in decarbonisation and the provision of efficient heating and cooling in Europe. However, whereas these systems have achieved high penetration rates in colder climates of Northern, Central and Eastern Europe, they remain marginal in milder climates of Southern Europe. In terms of network design, district heating and cooling systems can be configured in

Joachim Wielandt’s petition for a privilege to print and sell 97 different books for 30 years (22 July 1721) and the following report by the University Consistory reveal the increasingly complex dynamic between royal policies and market realities in Denmark-Norway at the beginning of the eighteenth century. Read together, the petition and report highlight how ownership of printed texts was negotia

This thesis defends a naturalistic interpretation, and offers a critical analysis, of the views of David Hume on the subject of free will and moral responsibility. A central theme is that Hume's views should be understood and assessed in relation to P.F. Strawson's influential paper "Freedom and Resentment" (1962). The work in this thesis lays the foundation for "Freedom and Moral Sentiment: Hume'

The tumour immune microenvironment (TIME) in breast cancer is acknowledged with an increasing role in treatment response and prognosis. With a growing number of immune markers analysed, digital image analysis may facilitate broader TIME understanding, even in single-plex IHC data. To facilitate analyses of the latter an open-source image analysis pipeline, Tissue microarray MArker Quantification (

Background: Platelet transfusions are given to preterm infants with severe thrombocytopenia aiming to prevent haemorrhage. The PlaNeT2/MATISSE trial revealed higher rates of mortality and/or major bleeding in preterm infants receiving prophylactic platelet transfusions at a platelet count threshold of 50 × 109/L compared to 25 × 109/L. The extent to which this evidence has been incorporated into c

Background: Palliative care needs in patients with cardiovascular diseases (CVD) are expected to increase. For the planning of equitable palliative care, it is important to understand where people with CVD die. The aim was to examine trends in place of death, associated factors including utilization of specialized palliative services, and to what extent longitudinal development is influenced by na

Breastfeeding provides many health benefits, but its impact on respiratory health remains unclear. This study addresses the complex and dynamic nature of the mother-milk-infant triad by investigating maternal genomic factors regulating human milk oligosaccharides (HMOs), and their associations with respiratory health among human milk-fed infants. Nineteen HMOs are quantified from 980 mothers of th

Isolated mosasaur teeth and vertebrae recovered from beds of the Guadalupe Group of central Boyacá, Colombia, are reported. A partial tooth crown identified as Globidens sp., found in the Labor-Tierna Formation (Maastrichtian), represents the first report of this genus from northern South America and its most equatorial occurrence. A tooth crown recovered from the Plaeners Formation (upper Campani

Children born to enemy soldiers, so-called “children born of war,” are vulnerable to displacement. The contested repatriations of the children of Scandinavian mothers and foreign fighters from Syria in the wake of the fall of the “Islamic state” in March 2019 are point in case. Norway, Denmark, and Sweden at first delayed and then only hesitantly or selectively supported their return – as Norway a