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Development of a thermal micro-biosensor fabricated on a silicon chip

In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the c

Reconsidering regional structural conditions for industrial renewal

This article develops a more comprehensive understanding of innovation-based renewal of industries from a structural perspective. Arguably, established perspectives offer rather simplistic views, portraying structures as either enabling or constraining for certain forms of regional industrial change. Inspired by work in organizational institutionalism on ‘institutional infrastructures’, this artic

Trip Reports: Exploring the Experience of Psychedelic Intoxication

Experiences of intoxication elude scientific research because of their immediate and ‘inner’ nature for the intoxicated individual. In this chapter, we show how ‘trip reports’ – reports of psychedelic intoxication – from online drug information forums and libraries allow for further understanding the experience of psychedelic intoxication from LSD, DMT and psilocybin by examining psychonauts’ (i.e

Purification and HDL-like particle formation of apolipoprotein A-I after co-expression with the EDDIE mutant of Npro autoprotease

Apolipoprotein A-I (ApoA-I) is the major protein constituent of high-density lipoprotein particles, and as such is involved in cholesterol transport and activation of LCAT (the lecithin:cholesterol acyltransferase). It may also form amyloidal deposits in the body, showing the multifaceted interactions of ApoA-I. In order to facilitate the study of ApoA-I in various systems, we have developed a pro

Korruption, utländsk påverkan och frihetstidens styrelseskick : En politisk historia

Allt sedan det amerikanska presidentvalet 2016 har det runt om i världen pågått en intensiv diskussion om utländska påverkansoperationer och hur och med vilken framgång främmande makter i det fördolda har sökt påverka demokratiska val, politisk opinion och politiska beslut i olika länder, däribland Sverige. Forskare, debattörer och politiker har särskilt framhållit att den nya informationsteknolog

The Gaia-ESO Survey : Galactic evolution of lithium from iDR6

Context. After more than 50 years, astronomical research still struggles to reconstruct the history of lithium enrichment in the Galaxy and to establish the relative importance of the various 7Li sources in enriching the interstellar medium (ISM) with this fragile element. Aims. To better trace the evolution of lithium in the Milky Way discs, we exploit the unique characteristics of a sample of op

Extending the Proteomic Characterization of Candida albicans Exposed to Stress and Apoptotic Inducers through Data-Independent Acquisition Mass Spectrometry

Candida albicans is a commensal fungus that causes systemic infections in immunosuppressed patients. In order to deal with the changing environment during commensalism or infection, C. albicans must reprogram its proteome. Characterizing the stress-induced changes in the proteome that C. albicans uses to survive should be very useful in the development of new antifungal drugs. We studied the C. al

The impact of peripheral artery disease on major adverse cardiovascular events following myocardial infarction

Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regressio

Accuracy of magnetic resonance imaging staging of tumour and nodal stage in rectal cancer treated by primary surgery : a population-based study

Aim: The preoperative stage of rectal cancer is an important prognostic factor affecting treatment recommendations. Currently, magnetic resonance imaging (MRI) is used for clinical staging to identify patients who should be recommended for neoadjuvant oncological treatment. The aim of this work was to investigate the accuracy of the preoperative T- and N-stage and also involvement of the mesorecta

Luminescence of ODC(II) in quartz and cristobalite glasses

The results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environmThe results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environm

Sensor Networks Tdoa Self-Calibration : 2d Complexity Analysis and Solutions

Given a network of receivers and transmitters, the process of determining their positions from measured pseudoranges is known as network self-calibration. In this paper we consider 2D networks with synchronized receivers but unsynchronized transmitters and the corresponding calibration techniques, known as Time-Difference-Of-Arrival (TDOA) techniques. Despite previous work, TDOA self-calibration i

Introduction

There is a flourishing use of long-term analysis around the economic challenges generated by natural resources exploitation (Badia-Miró et al., 2015; Bebbington et al., 2018; Mosley, 2017).

Pain in rheumatoid arthritis : a seven-year follow-up study of pain distribution and factors associated with transition from and to chronic widespread pain

Objective: To study transitions from and to chronic widespread pain (CWP) over 7 years in patients with rheumatoid arthritis (RA). Method: Two postal questionnaires were sent to patients included in the BARFOT (Better Anti-Rheumatic Pharmacotherapy) study, the first in 2010 and the second in 2017. The questionnaires assessed pain, number of tender and swollen joints, functional disability, health-