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Design of a national patient-centred clinical pathway for sepsis in Sweden

Background: The World Health Organization has adopted a resolution on sepsis and urged member states to develop national processes to improve sepsis care. In Sweden, sepsis was selected as one of the ten first diagnoses to be addressed, when the Swedish government in 2019 allocated funds for patient-centred clinical pathways in healthcare. A national multidisciplinary working group, including a pa

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Översättning och bearbetning till nederländska av min biografi om drottning Kristina.

Sustainable local journalism: role of engagement and interaction in building trust in local journalism

The object of the study is to discuss how methods for increase interaction with communities can contribute to find ways for building relationships between local journalists and publics. Also, the study aims to display how trust can contribute to strategies for social sustainability of local journalism. Exploring new ways of studying communication and interactions in media and journalism is of high interest considering that we live in a constantly transforming media landscape. To build sustainable journalism and media organizations requires a holistic approach of the development involving audience, news producers and other stakeholders.This panel originates from studies applying action research o

Local News in a Changing Media Environment : Impact of Hyper Local News – Case of Swedish Local Media

Hyperlocal news appears often in discussion about the future of the news media and potential alternative models. There is a strong need to analyse development of hyper-local news initiatives to better understand the needs of this sector, possibilities and challenges of collaboration between the community and media initiatives. It is important to study the phenomena in various cultural and social cHyper-local news appears often in discussion about the future of the news media and potential alternative models. There is a strong need to analyse development of hyper-local news initiatives to better understand the needs of this sector, possibilities and challenges of collaboration between the community and media initiatives. It is important to study the phenomena in various cultural and social

CIRLEM : a synergic integration of Collective Intelligence and Reinforcement Learning in Energy Management for enhanced climate resilience and lightweight computation

A novel energy management (EM) approach is introduced, integrating core elements of collective intelligence (CI) and reinforcement learning (RL) and called CIRLEM. It operates by distributing a flexibility signal from the energy supplier to agents within the grid, prompting their responsive actions. The flexibility signal reflects upon the collective behaviour of the agents in the grid and agents

Plasma proteomic changes in response to exercise training are associated with cardiorespiratory fitness adaptations

Regular exercise leads to widespread salutary effects, and there is increasing recognition that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited data exist regarding the plasma proteomic changes that occur in response to regular exercise. Here, we perform large-scale plasma proteomic profiling in 654 healthy human study participants before and after a supe

Instudering och utmaningar - Instuderingen av nya stycken musik och utmaningar som inträffar.

Som musiker är instuderingen av nytt stycke musik något vi kommer att ha med oss genom våra hela liv. Att förbereda något nytt kan till tider kännas skrämmande om det har stora utmaningar som vi inte kännas oss bekväma med och gör i några fall att man fastnar i cirkel av frustration som kan vara svår att komma ut ur. Genom mina år som gitarrist har jag ofta känt att vissa musikstycken är för svårAs a musician, the study of a new piece of music is something that we will have with us throughout our whole lives. Preparing something new can at times feel daunting if it has major challenges that we do not feel comfortable with and in some cases make you get stuck in a circle of frustration that can be difficult to get out of. Throughout my years as a guitarist, I have often felt that some pie

Applying Unique Molecular Indices with an Extensive All-in-One Forensic SNP Panel for Improved Genotype Accuracy and Sensitivity

One of the major challenges in forensic genetics is being able to detect very small amounts of DNA. Massively parallel sequencing (MPS) enables sensitive detection; however, genotype errors may exist and could interfere with the interpretation. Common errors in MPS-based analysis are often induced during PCR or sequencing. Unique molecular indices (UMIs) are short random nucleotide sequences ligat

Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk : a Mendelian randomization study

Background: C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect of CNP on CVD risk using the Mendelian randomization (MR) framework. Methods: Instrumental variables mimicking the effects of pharmacological intervention on

Creating a Sustainable Competitive Position: Ethical Challenges for International Firms

The importance of ethical practices and a sustainable competitive position is being increasingly emphasised by all types of business and across all industries. The chapters collected in Creating a Sustainable Competitive Position discuss how international firms work with sustainable strategies and their relationship with the society and environment while exploring the different opportunities and c

Framework for Assessing the Feasibility of Carbon Dioxide Removal Options Within the National Context of Germany

Removal of carbon dioxide from the atmosphere will be required over the next decades to achieve the Paris Agreement goal of limiting global warming to well below 2°C aiming at not exceeding 1.5°C. Technological and ecosystem-based options are considered for generating negative emissions through carbon dioxide removal (CDR) and several nations have already included these in their Long-Term Low Gree

Predicting Protein Stability with Machine Learning

Protein stability is a property of high importance and is of interest in a variety of fields. It determines if a protein has its native fold and can be of influence in certain diseases such as Parkinson's and Alzheimer's disease. It can also be of interest in an industrial setting to optimise the stability of enzymes in certain physicochemical environments. Recent developments in machine l

There are more than four : Andy Fabo, Robert Flack, Tim Jocelyn, Chrysanne Stathacos

For me, life in this city begins and ends with artist-initiated networks, where energies and programmes are constantly opening and ending, keeping pace with the rate at which artist’s studios are closed and relocated. These networks establish where work is developed, shown, or both, and they affirm what is missing as much as what is made. The affective affinities that enable these associations als

How do We make a We

Curated by Claudia De la Torre and Gregorio Magnani in collaboration with the participants of the 23th edition CSAV - Artists’ Research Laboratory, the publication reflects on the experiences shared at the laboratory and on its overall theme. Through individual and collaborative contributions it investigates how sound, performance, and language may become tools in the creation of a “we” capable of

Variability of soil water content along a transect in a desert area

Spatial variation patterns of soil water content are investigated along a bare soil transect covering a crest-to-crest spacing (about 60 m) in a shifting sand dune area. Soil water content analyses from gravimetrical soil sampling and neutron probe observations are shown to give different information regarding variability patterns. Gravimetrical sampling displays a large effect of a small rainfall

Topographical and coastal influence on spatial precipitation patterns in Tunisia

The spatial properties of the correlation structure based on daily rainfall data from 67 stations throughout Tunisia over a 5‐year period are examined. The correlation structure is generally markedly anisotropic as influenced by topography and the coast. These two factors seem to influence the correlation pattern differently during different months. The mean areas within the 0.7 correlation isolin

An analysis of the rainfall time structure by box counting-some practical implications

The scale-invariant behavior of the rainfall time structure was investigated by applying the box counting method to rainfall time series. Two years of minute observations, 90 years of daily observations and 170 years of monthly observations were analyzed and the results were interpreted and related to physical properties of the rainfall process. This paper discusses the question of whether an hypo