Craniopharyngiomas (CPs) are rare primary brain epithelial tumors arising in the suprasellar region from remnants of Rathke's pouch. About 50% originate at the level of the third ventricle floor, including the hypothalamus (HT). CPs are characterized by a low proliferation rate and symptoms due to mass effect and local infiltration and are managed primarily with surgery and radiotherapy. Gross tot

Vi har mycket att lära från länder som Kanada, där civilsamhället spelar en betydligt mer framträdande roll i integrationsarbetet. Det skriver professor emeritus Benny Carlson samt Oskar Adenfelt och Johanna Hemberg, Fores.

Benny Carlson skriver här om Migrationsverkets långa handläggningstider, som kostar samhället pengar: ”Det finns de – flyktingar, anhöriga, studerande, arbetskraftsinvandrare – som är välutbildade och inget hellre vill än att bli självförsörjande, nyttiga och välintegrerade svenska medborgare men som stöter på patrull vart än de vänder sig.”

This article presents new measurements of the fragmentation properties of jets in both proton–proton (pp) and heavy-ion collisions with the ALICE experiment at the Large Hadron Collider (LHC). We report distributions of the fraction zr of transverse momentum carried by subjets of radius r within jets of radius R. Charged-particle jets are reconstructed at midrapidity using the anti-k T algorithm w

This paper presents a measurement of b-jet production in Pb+Pb and pp collisions at sNN=5.02 TeV with the ATLAS detector at the LHC. The measurement uses 260 pb - 1 of pp collisions collected in 2017 and 1.4 nb - 1 of Pb+Pb collisions collected in 2018. In both collision systems, jets are reconstructed via the anti- kt algorithm. The b-jets are identified from a sample of jets containing muons fro

Context: Whether patients with Cushing disease (CD) in remission have increased mortality is still debatable.Objective: To study overall and disease-specific mortality and predictive factors in an unselected nationwide cohort of patients with CD.Design, patients, and methods: A retrospective study of patients diagnosed with CD, identified in the Swedish National Patient Registry between 1987 and 2

This thesis unfolds a journey into the realm of cloud integrated systems. More specifically, it explores the transformational role of diverse cloud infrastructure, be it public or private, centralized or edge-based, when integrated into traditional systems. In this transformation, the cloud assumes the vital role of controllers. Inevitably, this shift towards cloud integration also brings into pla

Efter Tysklands enande är Harz åter en turistmagnet med mycket att erbjuda: vackra städer, fina vyer, historia och mystik. För en skåning som vill jämföra korsvirkeshus är städerna dessutom ett eldorado. Följ med på en resa i en avlägsen släktings fotspår.

ObjectiveSomapacitan is a reversible albumin-binding growth hormone (GH) derivative, developed for once-weekly administration. This study aimed to evaluate the safety of once-weekly somapacitan vs once-daily Norditropin®. Local tolerability and treatment satisfaction were also assessed.Design26-week randomized, controlled phase 3 safety and tolerability trial in six countries (Nbib2382939).Methods

BackgroundOrthostatic hypotension (OH) occurs when blood pressure regulation fails. The underlying molecular mechanism of OH remain largely unexplored. Endostatin is a biologically active molecule cleaved by matrix metalloproteinases, elastases and cathepsins from collagen XVIII in the extracellular matrix and inhibits angiogenesis. Circulating levels of endostatin have been proposed to be involve

Context: GH replacement in adult GH-deficient patients may cause insulin resistance, raising concerns of potential increased risk of developing diabetes mellitus (DM).Objective: Our objective was to assess DM prevalence and incidence in the international Hypopituitary Control and Complications Study (HypoCCS) surveillance database.Design and participants: GH-treated patients enrolled into HypoCCS

Over the last decade, scholarly attention has turned to the humanities’ collective past with renewed energy and sense of purpose. As a result, a new field of research, the history of the humanities, has crystalized and received broad international attention. In this forum, we take a special interest in the question of where the history of the humanities is heading. And where do we want it to go? I

Background: We analysed the COMparison Between All immunoTherapies for Multiple Sclerosis (NCT03193866), a Swedish nationwide observational study in relapsing-remitting multiple sclerosis (RRMS), to identify trajectories of processing speed and physical disability after disease-modulating therapy (DMT) start. Methods: Using a group-modelling approach, we assessed trajectories of processing speed w

Stochastic optimization methods are commonly used in the design process of power electronic systems. These require models of crucial parts of the system which are both scalable and computationally efficient. This paper presents thermal models for traction inverter power modules based on scalable chip area that provide high speed of execution and accuracy. The thermal model includes chip-chip inter

Background: There are contradictory research findings regarding whether individuals with Autism Spectrum Disorders (ASDs) are more or less likely to commit crimes. The aims of the current study were to: (1) Describe psychiatric and crime-related characteristics of a large group of offenders with ASD who had undergone a Forensic Psychiatric Investigation (FPI). (2) Identify clinical subgroups among

The aim was to explore political representatives' experiences of child participation in decision-making processes in municipalities. Interviews were conducted with Swedish politicians (n = 7) representing four municipalities. Qualitative content analysis was used to analyse the data. Politicians had experiences in child participation and methods for involving children and young people in the pract

Currently, it is accepted that animal locomotion is controlled by a central pattern generator in the spinal cord. Experiments and models show that rhythm generating neurons and genetically determined network properties could sustain oscillatory output activity suitable for locomotion. However, current central pattern generator models do not explain how a spinal cord circuitry, which has the same b