The aim of this study was to evaluate the predictive value of intratumoural microvessel density in breast cancer. We studied immunohistochemically primary tumours of 104 patients with metastasised breast cancer who took part in a randomised multicentre trial comparing docetaxel to sequential methotrexate and 5-fluorouracil. Vessels were highlighted with factor VIII staining and counted microscopic

Since capital needs are high when investing in Renewable Energy Technologies (RET), well adapted financial schemes are essential, including well fitted financial support. Supporting the dissemination of RET means supporting people, not technologies. Though, support mechanism have to be adapted to people not to technologies. A recent study for the European Parliament compares support mechanisms for

Background: Chronic heart failure (CHF) is associated with a high risk of sudden cardiac death (SCID). Most frequently SCID occurs in patients with NYHA class II and III. Aim: To evaluate the influence of prolonged carvedilol therapy on SCID risk in CHF patients. Methods: The study included 86 patients (81 men and 5 women) aged 56.8 +/- 9.19 (35-70) years with CHF in NYHA class II and III receivin

Purpose : To study how patients with fibromyalgia (FM) experienced physiotherapy group treatment comprising pool exercise and education. Method : Nineteen patients with FM were interviewed and the transcribed interviews were analysed using a phenomenological life-world approach. The participants' mean age was 45 years and their mean symptom duration was 10 years. Results : Physiotherapy group trea

The Prototype Repository, at the Aspo HRL (Hard Rock Laboratory), is a demonstration project for the deposition of spent nuclear fuel, and provides a full-scale reference for testing predictive models relating to a spent nuclear fuel repository, both its individual components as well as the complete system. The final layout involves six deposition holes, four in an inner section and two in an oute

The 3-ethoxycarbonyl-4-quinolone compound I has previously been identified via a database search as an interesting lead compound for ligand binding at the benzodiazepine site of GABA(A) receptors (Kahnberg et al. J. Mol. Graphics Modelling 2004, 23, 253-261). Pharmacophore-guided optimization of this lead compound yielded a number of high-affinity ligands for the benzodiazepine site including comp

Anuran sex ratio at breeding sites is typically male biased. Such sex ratios may be due to poor female survival, to females not breeding as frequently as males and/or to males becoming sexually mature earlier than females. In the present study, the first two factors are analyzed in a common toad (Bufo bufo) population in southern Sweden. Toads were captured, marked and recaptured at the breeding s

Biomedical Optics as an interdisciplinary field of science has been developed during many years and is experiencing tremendous growth, to cover a wide range of optical techniques and methods, utilized for medical therapeutic and diagnostic purposes. Biomedical optics contributes in the introducing methods and creation of devices used in healthcare of various specialties, such as ophthalmology, car

In this paper, we investigate the analog front-end imperfection in multi-band orthogonal frequency division multiplexing (MB-OFDM) ultra-wideband (UWB) systems and propose a joint estimation and compensation scheme. The estimation of CFO and SFO is presented on frequency domain, which is robust to frequency dependent I/Q imbalance. After that, I/Q imbalance and channel response is jointly estimate

Popular Abstract in Swedish Bildgivande system har en allt mer framträdande roll inom sjukvård och medicinsk forskning. En del av dessa system fungerar genom att en patient eller ett försöksdjur injiceras med ett läkemedel märkt med ett radioaktivt ämne, och sedan mäts den strålning som detta ämne avger för att skapa en bild av var ämnet, och därmed läkemedlet, befinner sig. Det finns både system Molecular imaging, both in vivo and ex vivo, is playing an increasingly important role in preclinical medical research. When using radionuclide-labeled tracers, e.g. in the development of radiopharmaceuticals for diagnostic imaging or for radionuclide therapy, quantitative in vivo imaging can be performed using emission tomography. Quantitative autoradiography of thin tissue sections is employed t

The objective of this study was to find risk factors for suicide by looking for clinical and care/treatment consumption differences between 15 hospitalized suicide attempters, who later committed suicide ("completers''), and 15 suicide attempters who did not ("non-completers''), matched according to sex, age and principal diagnosis. Completers had significantly more often attempted suicide after t

Large and powerful ocean predators such as swordfishes, some tunas, and several shark species are unique among fishes in that they are capable of maintaining elevated body temperatures (endothermy) when hunting for prey in deep and cold water [1-3]. In these animals, warming the central nervous system and the eyes is the one common feature of this energetically costly adaptation [4]. In the swordf

A methodology for safety verification of continuous and hybrid systems using barrier certi.ficates has been proposed recently. Conditions that must be satisfi.ed by a barrier certi. cate can be formulated as a convex program, and the feasibility of the program implies system safety in the sense that there is no trajectory starting from a given set of initial states that reaches a given unsafe regi

Hypoglycaemia (median venous blood glucose 1.8 mmol/l; range 1.6-2.3) was induced by an intravenous infusion of regular insulin in eight patients with Type 1 (insulin-dependent) diabetes mellitus (age 28.0 +/- 7.4 years; mean +/- SD, duration 15.5 +/- 5.1 years) and in 12 age-matched healthy male control subjects. Multi-channel frequency analysis of electroencephalogram (electrophysiologic brain m