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Transcription of integrated DNA from viruses or transposable elements is tightly regulated to prevent pathogenesis. The Human Silencing Hub (HUSH), composed of Periphilin, TASOR and MPP8, silences transcriptionally active viral and endogenous transgenes. HUSH recruits effectors that alter the epigenetic landscape and chromatin structure, but how HUSH recognizes target loci and represses their expr
In this paper, we introduce an unreported multiphonic harmonic on the vibraphone produced in a manner similar to the way that struck harmonics are produced. For the vibraphone, a common technique in contemporary literature features the isolation and production of a single harmonic (h04) in the lower octave. However, through experiments by both authors on different vibraphones, an unreported multip
Den svenska dataspelsbranschen är en ”ung” bransch med en kraftig tillväxt de senaste åren. 2020 omsatte branschen 35 miljarder kronor och har omnämnts för ”den nya basindustrin”. I media har frasen ”det svenska spelundret” använts för att beskriva branschen som en framgångssaga. Antalet anställda i branschen har fördubblats under de senaste fem åren, vilket är ett tecken på att branschenupplevs s
Background: Migratory birds differ markedly in their migration strategies, particularly those performing short- versus long-distance migrations. In preparation for migration, all birds undergo physiological and morphological modifications including enlargement of fat stores and pectoral muscles to fuel and power their flights, as well as cardiovascular and biochemical adjustments that improve lipi
Fungal infections are a major health problem that often begin in the gastrointestinal tract. Gut microbe interactions in early childhood are critical for proper immune responses, yet there is little known about the development of the fungal population from infancy into childhood. Here, as part of the TEDDY (The Environmental Determinants of Diabetes in the Young) study, we examine stool samples of
Question: When evaluating forests in terms of their biodiversity, distinctiveness and naturalness, the affinity of the constituent species to forests is a crucial parameter. Here we ask to what extent are vascular plant species associated with forests, and does species’ affinity to forests vary between European regions?Location: Temperate and boreal forest biome of Northwestern and Central Europe.
The presence of Shii communities in Europe is increasingly felt, especially as they establish independent religious and social infrastructures. Supporters of different Shii–Islamist political parties have established transnational links connecting diasporic communities with their countries of origin. These links have shaped and been shaped by religious, political and social dynamics in the Middle
Drawing on a study of Shi‘i ritual lamentation in Lebanon, this article examines how religious actors and pious publics employ literary, recitational, theatrical, and socio-technological methods to cultivate imaginal engagements with the other-worldly. These methods are analyzed, demonstrating how they locate pious Shi‘is in religious meta-narratives that transcend the linearity of time, taking pl
This intervention seeks to challenge the notion that ungovernable people and places are aberrations to theorizations of governance. By spatializing and grounding theory through ethnographic, multi-sited and actor-focused inquiry, we investigate the techniques and practices of governing territories and people that are deployed in four sites in the Middle East and North Africa. We highlight the impa
Characterizing the diversity and structure of host-parasite communities is crucial to understanding their eco-evolutionary dynamics. Malaria and related haemosporidian parasites are responsible for fitness loss and mortality in bird species worldwide. However, despite exhibiting the greatest ornithological biodiversity, avian haemosporidians from Neotropical regions are quite unexplored. Here, we
Purpose: This article presents a discussion of how librarians' engagement in certain social movements manifests itself in public libraries, how librarians justify their engagement with specifically the LGBT + movement and the climate movement and what it might entail in terms of legitimacy. Design/methodology/approach: Besides an extensive international literature on libraries and climate/LGBT + i
This article analyses Swedish social workers’ accounts of custody when a parent is in remand prison or prison due to homicidal violence that has resulted in the death of the other parent. How do social workers justify or excuse assessments of custody and custody transfers? What legal dilemmas can be discerned? The empirical material comprises six group interviews with 14 Swedish social workers bas
This chapter outlines how the history of health care in Syria has shaped the way in which wartime health care has been delivered and controlled. The chapter analyzes the claim by humanitarian organizations to a form of neutrality in the Syrian war, which was ultimately incompatible with the way the Syrian state and the opposition saw aid delivery as part of the battle for statehood. It also mentio
