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Several studies have evaluated various ML techniques and found promising results in classifying bug reports. However, these studies have used different evaluation designs, making it difficult to compare their results. Furthermore, they have focused primarily on accuracy and did not consider other potentially relevant factors such as generalizability, explainability, and maintenance cost. These two
Mobile stroke units (MSUs), which are specialized ambulances equipped with a brain imaging device and staffed with trained healthcare personnel, have the potential to provide rapid on-site diagnosis and treatment for stroke patients. However, efficient access to prehospital stroke care requires optimizing the placement of MSUs. The MSU allocation problem has been previously solved using a traditio
The combustion of conventional Jet A, alongside two alternative jet fuels, C1 and C5, is simulated with Large Eddy Simulations (LES) in a generic single-cup spray combustor during idle and cruise conditions. The spray is modeled using Lagrangian particle tracking and the combustion chemistry of each fuel is modeled by skeletal reaction mechanisms. The volatility and atomizability of each fuel dire
A new microphysical treatment that includes aerosol–cloud interactions and secondary ice production (SIP) mechanisms is implemented in the convection scheme of the Community Atmosphere Model, version 6 (CAM6). The approach is to embed a 1D Lagrangian parcel model in the bulk convective plume of the existing deep convection parameterization. Aerosol activation, growth processes including collision/
Background: Combined CDK4/6 inhibitor (CDK4/6i) and endocrine therapy significantly improve the outcome of patients with advanced estrogen receptor-positive (ER+) breast cancer. However, resistance to this treatment and disease progression remains a major clinical challenge. High expression of the receptor tyrosine kinase REarranged during Transfection (RET) has been associated with resistance to
Introduction: Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain. Methods:
The advancement of disease-modifying treatments (DMTs) for Alzheimer's disease (AD), along with the approval of three amyloid-targeting therapies in the US and several other countries, represents a significant development in the treatment landscape, offering new hope for addressing this once untreatable chronic progressive disease. However, significant challenges persist that could impede the succ
During the evolution of parasites, co-speciation and host-range expansion are thought to play roles in establishing associations with hosts, while sorting events can lead to dissolution of those associations. To address the roles of these processes, we focus on avian haemosporidian parasites infecting hosts of the intensively studied great tit species complex. We estimated the phylogeography of li
Warfare has been commonly associated with increasing levels of inflation, with important implications for tax systems. In this chapter, we first review the literature on war finance and inflation, considering both the fiscal causes of inflation during wartimes and the effects of inflation on tax revenues. Second, we focus on developments in the income tax during the World Wars, building upon our p
This paper examines the distributive effects of personal income taxation in Sweden, the United Kingdom, and the United States during the first half of the 20th century. We estimate the evolution of marginal and average effective tax rates across the income distribution and calculate the corresponding indices of progressivity and redistribution. Our results show that redistribution through income t
In situ catalysis studies typically correlate catalytic function and majority surface structures, but neglect that difficult-to-detect minority structures might govern catalysis. Here we use an oscillating CO:O2 gas composition to drive structural oscillations on a catalytically active Pd(100) surface and collect X-ray photoelectron spectroscopy data at high measurement frequency to demonstrate th
