This article presents some results from a large monitoring campaign performed in 22 buildings around the world as part of International Energy Agency (IEA) Task 50 “Advanced lighting solutions for retrofitting buildings”. This article mainly addresses the work of Subtask D, which aims to demonstrate sound lighting retrofit solutions in a selection of representative, typical Case Studies. In order

Today the identification of lead structures for drug development often starts from small fragment-like molecules raising the chances to find compounds that successfully pass clinical trials. At the heart of the screening for fragments binding to a specific target, crystallography delivers structural information essential for subsequent drug design. While it is common to search for bound ligands in

Fragment-based lead discovery (FBLD) has become a pillar in drug development. Typical applications of this method comprise at least two biophysical screens as prefilter and a follow-up crystallographic experiment on a subset of fragments. Clearly, structural information is pivotal in FBLD, but a key question is whether such a screening cascade strategy will retrieve the majority of fragment-bound

Laser-induced fluorescence from carbon atoms, excited at the two-photon resonances around 280 nm, has been detected in fuel-rich hydrocarbon flames together with Swan band emission from the C2 radical, which was non-resonantly excited at the same wavelengths. The emission from the C atom and from the C2 molecule exhibited several similarities, indicating a possible common photo-chemical origin.

Att leva med en autoimmun sjukdom som typ 1-diabetes innebär att man tvingas till ställningstaganden som en frisk individ sällan eller aldrig behöver ta i beaktande. Dessa ställningstaganden kan utifrån sett tyckas vara obetydliga men är för diabetikern livsviktiga. Denna artikel är skriven utifrån ett första-personsperspektiv och lyfter fram aspekter som blir en del i en slags överlevnadsstrategi

Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly 50 Gy. We pooled data from 12 studies of thyroid cancer patients who were exposed to radiation in childhood (ages

This study focusses on the hydrogeology of Urema Graben, especially possible interactions between surface water and groundwater around Lake Urema, in Gorongosa National Park (GNP). Lake Urema is the only permanent water source for wildlife inside GNP, and there are concerns that it will disappear due to interferences in surface-water/groundwater interactions as a result of changes in the hydraulic

Urban environments are expanding rapidly, and with urbanization come both challenges and opportunities for wildlife. Challenges include combating the anthropogenic disturbances such as light, noise and air pollution and lower availability of natural food sources. The benefits are many, including the availability of anthropogenic food sources, breeding boxes and warmer temperatures. Thus, depending

This essay returns to the extensive scholarly debate surrounding the lyrics and fragments which Percy Bysshe Shelley composed for Jane Williams, or with her in mind, during the last six months of his life. It takes its point of departure in what it defines as “the problem of the Jane Williams poems” – the difficulty, faced by biographers, editors, and critics alike, of mapping the relationship bet