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Novel multi-target compounds in the quest for new chemotherapies against Alzheimer's disease : An experimental and theoretical study

The lack of any effective therapy along with the aging world population anticipates a growth of the worldwide incidence of Alzheimer's disease (AD) to more than 100 million cases by 2050. Accumulation of extracellular amyloid-β (Aβ) plaques, intracellular tangles in the brain, and formation of reactive oxygen species (ROS) are the major hallmarks of the disease. In the amyloidogenic process, a β-s

Food industry applications

This article provides an overview on established membrane applications in the food industry and focuses on applications of membrane processes in the production of beer, wine, fruit juice, food additives, and dairy products such as milk, whey, and cheese. Furthermore, as the food industry is a highly water consuming industry one section of this article is dedicated to water preparation and wastewat

4D porosity evolution during pressure-solution of NaCl in the presence of phyllosilicates

Pressure-solution creep is one of the most common crustal deformation mechanisms, inducing changes in the porosity and permeability of rocks. For a variety of rock types undergoing pressure solution, it has been shown that the presence of phyllosilicates may significantly enhance the rate of the pressure-solution process. In this experimental investigation, we present 4-dimensional (three dimensio

Antioxidants from plants protect against skin photoaging

Exposure to UV light triggers the rapid generation and accumulation of reactive oxygen species (ROS) in skin cells, with consequent increase in oxidative stress and thus in photoaging. Exogenous supplementation with dietary antioxidants and/or skin pretreatment with antioxidant-based lotions before sun exposure might be a winning strategy against age-related skin pathologies. In this context, plan

Development of hydrophilic membranes for challenging separation applications

Membrane fouling and its control is one of the most critical parameters in the application of membrane processes. The degree of fouling depends on the application and on industrial scale, fouling is often observed as reduction in plant capacity over time. One approach to reduce fouling for the pressure driven processes microfiltration and ultrafiltration is to use hydrophilic membranes. This paper

Membrane processes in the separation and utilisation of wood biomass in the context of the pulp and paper industry

The recent developments in the field of biorefineries open new opportunities for the pulp and paper industry to diverse from classical carton and paper production to bio-based chemicals. The trend is thus to use the three key wood components hemicelluloses, lignin and cellulose as raw materials for production of a wide range of biochemicals. A key success factor is the integration of energy-effici

Exercise benefits in cardiovascular disease : beyond attenuation of traditional risk factors

Despite strong scientific evidence supporting the benefits of regular exercise for the prevention and management of cardiovascular disease (CVD), physical inactivity is highly prevalent worldwide. In addition to merely changing well-known risk factors for systemic CVD, regular exercise can also improve cardiovascular health through non-traditional mechanisms. Understanding the pathways through whi

Membrane opportunities in production and water loop of biorefineries based on lignocellulosic biomass

In recent years biorefineries using lignocellulosic biomass such as wood and agricultural residuals as raw material have gained significant interest since they avoid competition with food production. One of the key development areas of these lignocellulosic based biorefinery concepts is the integration low energy and high selective separation processes. Thus, membrane processes either as stand-alo