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Yttrande för remissen: Genomförandet av minimilönedirektivet (SOU 2023:36)

Samhällsvetenskapliga fakulteten vid Lunds universitet instämmer i huvudsak i utredningens slutsatser, men anser att regeringen i samarbete med arbetsmarknadens parter bör överväga åtgärder om kollektivavtalens täckningsgrad skulle börja sjunka och långt innan den kommer ned på tröskelvärdet 80%. Den svenska arbetsmarknadsmodellen vilar, förutom på en hög kollektivavtalstäckning, också på en hög o

Outcomes After Endovascular Aortic Intervention in Patients With Connective Tissue Disease

Importance: Endovascular treatment is not recommended for aortic pathologies in patients with connective tissue diseases (CTDs) other than in redo operations and as bridging procedures in emergencies. However, recent developments in endovascular technology may challenge this dogma. Objective: To assess the midterm outcomes of endovascular aortic repair in patients with CTD. Design, Setting, and Pa

Donanemab in Early Symptomatic Alzheimer Disease : The TRAILBLAZER-ALZ 2 Randomized Clinical Trial

Importance: There are limited efficacious treatments for Alzheimer disease. Objective: To assess efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid plaque. Design, Setting, and Participants: Multicenter (277 medical research centers/hospitals in 8 countries), randomized, double-blind, placebo-controlled, 18-month phase 3 trial that enrolled 1736 participants with

Test–Retest Reliability, Agreement and Criterion Validity of Three Questionnaires for the Assessment of Physical Activity and Sedentary Time in Patients with Myocardial Infarction

Regular physical activity (PA) and limited sedentary time (SED) are highly recommended in international guidelines for patients after a myocardial infarction (MI). Data on PA and SED are often self-reported in clinical practice and, hence, reliable and valid questionnaires are crucial. This study aimed to assess the test–retest reliability, criterion validity and agreement of two PA and one SED qu

Poorer survival after out-of-hospital cardiac arrest among cancer patients : a population-based register study

Aims: The association between cancer and survival after out-of-hospital cardiac arrest (OHCA) has not been thoroughly investigated. We aimed to address this knowledge gap using national, population-based registries. Methods and results: For this study, 30 163 patients with OHCA (≥18 years) were included from the Swedish Register of Cardiopulmonary Resuscitation. Through linkage to the National Pat

Investigating RNA toxicity using sister sRNAs OmrA & OmrB

Bacteria have harnessed a variety of self-acting toxic mechanisms to regulate plasmid maintenance, phage defense, expression of virulence factors, and antimicrobial resistance. It was thought that the expression of toxic proteins was the sole source of toxicity in bacteria. Recent studies have shown the potential for RNA to cause toxic growth phenotypes independent of toxic protein expression. How

Cross-class alliances and urban middle classes with peasant characteristics: : a historical-spatial approach to agency in territory-based rural mobilisations in Turkey

This article explores the complexities of agency in contemporary territory-based mobilisations in the countryside by focusing on water struggles in Turkey. Using a historical-spatial approach, it combines agrarian political economy analysis with human-nature interactions. Through an analysis of cash crop production and urban-rural interactions, this contribution argues that capitalist agrarian tra

Secure Sharing of Health-Related Data : Research Description of the VINTER, DELFIN, and HEIDA Projects

The need for secure and integrity-preserved data sharing has become increasingly important in the emerging era of changed demands on healthcare and increased awareness of the potential of data. In this research plan, we describe our path to explore the optimal use of integrity preservation in health-related data contexts. Data sharing in these settings is poised to increase health, improve healthc

Improvisational Practices in the Production of the Precarious Common Spaces on the Periphery of Europe

This article discusses improvisational cultural practices in relation to sedimented processes and other modes of production. During the economic crisis on Europe’s south edge, extreme neoliberal policies experimented with new modes of social engineering. Yet, even in the face of such coercive systems, emergent cultural practices were improvising, testing their own radical alternatives, and produci

Prospective Attitudes towards Respiratory Syncytial Virus (RSV) Vaccination : Validation of a Survey Instrument among Young Females in Jordan Pending Vaccine Authorization

In May 2023, the U.S. FDA advisors endorsed Pfizer’s pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce the burden of RSV-related respiratory disease, with previous studies showing its substantial medical and financial burden in Jordan. However, pregnant women may exhibit hesitancy to get vaccinated due to co

Intratumoral T-cell and B-cell receptor architecture associates with distinct immune tumor microenvironment features and clinical outcomes of anti-PD-1/L1 immunotherapy

Background Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-cells and T-cell receptor (BCR, TCR) repertoire affects the tumor immune microenvironment (TIME) and c

Possibilities and limits of modeling cavitation in high-pressure homogenizers – a validation study

High-pressure homogenizers are widely used in industrial processes to produce emulsions with small droplet sizes. During the process, cavitation occurs under industrial process conditions. In order to investigate the flow conditions inside a homogenizer geometry, CFD simulations are commonly used, since it is not possible to evaluate local flow conditions experimentally. However, these studies hav

Unleashing Ascl1 : Exploring Cross-Lineage Potential in Reprogramming and Regenerative Frontiers

In the era of stem cell research and regenerative medicine, understanding the regulatory networks that drive cellular reprogramming is fundamental. The study entitled ‘‘Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes’’ published in Stem Cell Reports sheds light on the remarkable versatility of Ascl1, a transcription factor known for its pivotal role in neu

Understanding how endothelial cells affect necrotizing soft tissue infections using an in vitro organotypic soft tissue infection model

Köttätande bakterier – från ofarlig till livshotande Bakterier är små levande ting som inte är synliga för blotta ögat. Alla bakterier orsakar inte sjukdom och vissa bakterier gör det om de befinner sig på fel plats i din kropp. Köttätande bakterier har fått sitt namn från att dom gör att vävnad i kroppen dör och när det sker orsakar dessa bakterier en mycket sällsynt och livshotande infektion. I

Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells

Pleural mesothelioma (PM) is an aggressive malignancy that develops in a unique tumor microenvironment (TME). However, cell models for studying the TME in PM are still limited. Here, we have generated and characterized novel human telomerase reverse transcriptase (hTERT)-transduced mesothelial cell and mesothelioma-associated fibroblast (Meso-CAF) models and investigated their impact on PM cell gr