Objectives: To assess secular trends in baseline characteristics of PsA patients initiating their first or subsequent biologic DMARD (bDMARD) therapy and to explore prescription patterns and treatment rates of bDMARDs from 2006 to 2017 in the Nordic countries. Methods: PsA patients registered in the Nordic rheumatology registries initiating any treatment with bDMARDs were identified. The bDMARDs w

Objective: To compare mortality risk over up to 14 years of follow-up in methotrexate-refractory patients with early RA randomized to a strategy starting with addition of infliximab vs addition of SSZ and HCQ. Methods: Data was from the two-arm, parallel, randomized, active-controlled, open-label Swefot trial in which patients with early RA (symptom duration

Objectives: To estimate the incidence and strength of association of extra-articular manifestations [EAMs, here: anterior uveitis (AU), IBD and psoriasis] in patients with AS, undifferentiated SpA (uSpA) and PsA, compared with controls. Methods: Three mutually exclusive cohorts of patients aged 18-69 years with AS (n = 8517), uSpA (n = 10 245) and PsA (n = 22 667) were identified in the Swedish Na

The electrification of road bound transport is to some extent limited by the large cost of the energy storage required on-board the vehicles, i.e., the cost of the battery. One way of reducing the required capacity of the on-board energy storage is to enable the possibility to supply the vehicles with electrical energy while it is moving, also called dynamic charging. The energy transfer is usuall

The clinical use of surface imaging has increased dramatically, with demonstrated utility for initial patient positioning, real-time motion monitoring, and beam gating in a variety of anatomical sites. The Therapy Physics Subcommittee and the Imaging for Treatment Verification Working Group of the American Association of Physicists in Medicine commissioned Task Group 302 to review the current clin

Objectives: Antibodies against anti-CD74 are related to axial spondyloarthritis (axSpA). The objectives were (i) to study IgA anti-CD74 in radiographic (r)-axSpA patients in the Backbone cohort and to calculate the sensitivity and specificity of anti-CD74, (ii) to study the fluctuation of IgA anti-CD74 levels in prospectively collected samples, and (iii) to explore the relation between IgA anti-CD

Artikeln fokuserar på hälso- och sjukvårdskuratorns arbete med att å ena sidan bemöta de känslor som barn och familjer kan känna efter att barnet diagnostiserats med den kroniska sjukdomen diabetes, å andra sidan han-tera olika byråkratiska processer som ska sörja för att barnets vårdbehov tillgodoses i familjens nya vardag. Arbetet riktas mot två olika världar som är inbördes beroende av varandraThe article focuses on the work of clinical social workers who, on the one hand, respond to the emotions that children and families experience after the child is diagnosed with the chronic disease diabetes, on the other hand, deal with various bureaucratic processes aimed at ensuring that the child’s medical needs are met in the family’s new life. The work is directed towards two different worlds

In elite soccer, training becomes more systematic and soccer clubs try to optimise their physiological training programs. Previous research has investigated many aspects of soccer, but research into the coaches’ own experiences and continuous improvement of physical training is lacking. The aim of this study was to describe the coaches’ experiences and their application of physical training in mal

PurposeTo investigate the effect of sex and load carriage on cardiorespiratory responses to high intensity exercise in male and female soldiers.MethodsSoldiers (9 women, 9 men) performed a graded treadmill test until exhaustion with no load (NL) and combat-gear with body armor (CG). Cohen's d effect sizes, paired t-tests and ANOVA were used to study differences between conditions. A mixed linear r

The aim of this study was to investigate the prevalence of depressive symptoms and associated factors in women who underwent treatments for fear of birth; internet-based cognitive therapy, counseling with midwives, continuity with a known midwife or standard care. A secondary analysis was performed using data collected from four samples of women identified with fear of birth and receiving treatmen

BACKGROUND: Co-morbidity is prevalent in women with fear of birth. Depressive symptoms and lack of prenatal attachment might influence the postpartum bonding between the mother and the new-born.AIM: To examine the underlying dimensions of the Postpartum Bonding Questionnaire and to investigate associations between depressive symptoms, prenatal attachment and postpartum bonding in women with fear o

Introduction: This study examines health-care costs attributed to dementia diseases in the 10 years prior to, during, and 6 years after diagnosis. Methods: Using administrative register data for people diagnosed with dementia (2010–2016) in southern Sweden (n = 21,184), and a comparison group without dementia, health-care costs over 17 years were examined using longitudinal regression analysis. Re

Using a spectrally resolved electron interferometry technique, we measure photoionization time delays between the 3s and 3p subshells of argon over a large 34-eV energy range covering the Cooper minima in both subshells. The observed strong variations of the 3s-3p delay difference, including a sign change, are well reproduced by theoretical calculations using the two-photon two-color random-phase

Identifying in situ hazardous materials can improve demolition waste recyclability and reduce project uncertainties concerning cost overrun and delay. With the attempt to characterize their detection patterns in buildings, the study investigates the prediction potential of machine learning techniques with hazardous waste inventories and building registers as input data. By matching, validating, an

X-ray free-electron lasers (XFELs) open a new era of X-ray based research by generating extremely intense X-ray flashes. To further improve the spectrum brightness, a self-seeding FEL scheme has been developed and demonstrated experimentally. As the next step, new-generation FELs with high repetition rates are being designed, built and commissioned around the world. A high repetition rate would si

This paper reports on nonlinear spectral broadening of 1.1 ps pulses in a gas-filled multi-pass cell to generate sub-100 fs optical pulses at 1030 nm and 515 nm at pulse energies of 0.8 mJ and 225 μJ, respectively, for pump-probe experiments at the free-electron laser FLASH. Combining a 100 kHz Yb:YAG laser with 180 W in-burst average power and a post-compression platform enables reaching simultan

The human cell nucleus serves as an important organelle holding the genetic blueprint for life. In this work, X-ray ptychography was applied to assess the masses of human cell nuclei using its unique phase shift information. Measurements were carried out at the I13-1 beamline at the Diamond Light Source that has extremely large transverse coherence properties. The ptychographic diffractive imaging

En debattartikel i Helsingborgs Dagblad som svarar på en tidigare artikel av tre liberala politiker.

The encouraging results of modern breast cancer care builds on tremendous improvements in diagnostics and therapy during the 20th century. Scandinavian countries have made important footprints in the development of breast diagnostics regarding technical development of imaging, cell and tissue sampling methods and, not least, population screening with mammography. The multimodality approach in comb