Several new polydentate and potentially dinucleating ligands have been synthesized in order to model the coordination environments of a number of structurally related dinuclear active sites in metalloenzymes, including methane monooxygenase, the ribonucleotide reductase R2 protein, urease, arginase, red kidney bean purple acid phosphatase and zinc phosphotriesterase.~ Ligands 1 and 2 have proven t

This article presents a political and legal analysis of the emergency brake in criminal law in Articles 82(3) and 83(3) TFEU. It suggests that the emergency brake offers a powerful discretionary prerogative for Member States seeking to protect the integrity of their criminal justice systems. This strong legal shield for Member States in the form of a ‘quasi-veto’ is contrasted with a tendency to d

Fluid anomalies were often considered as possible precursors before earthquakes. However, fluid properties at the surface can change for a variety of reasons, including environmental changes near the surface, the response of the superficial fluid system to loads associated with the mechanical nucleation of earthquake fractures, or as a result of transients in fluid flow from the depths. A key prob

Background: The textile dye mix (TDM) 6.6% pet. contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of p-phenylenediamine (PPD)-allergic dermatitis patients have shown positive patch test reactions to DO 3. There has been a discussion to exclude DO 3 from

In this study, the impacts of two different “methods” for teaching ethics as part of the religious education in the Swedish upper secondary school were compared by means of a non-randomized controlled trial in two parts, involving 542 students. The question was which “method” had the greatest capacity to generate long-term ethical awareness in the students. The intervention condition consisted of

This paper experimentally investigates heat dissipation of a heat pipe with phase change materials (PCMs) cooling in a multiple heat source system. Two heat sources are fixed at one end of the heat pipe. Considering that a heat sink cannot dissipate all the heat generated by two heat sources, various PCMs are used due to a large latent heat. Different materials in a container are wrapped outside o

Excessive risk-taking in markets can have devastating consequences as the latest financial crises have highlighted. In this paper, we ask whether markets as an institution encourages such excessive risk-taking. To establish causality, we isolate the effects of market interaction in a laboratory experiment keeping other possibly confounding factors constant. We find that the opposite is true. Marke

Combustion of fuel in diesel engines emits substances harmful to the environment such as soot. These emissions can be reduced by either in-cylinder treatments or after-treatments. One of the common in-cylinder treatments is multiple-injection, which divides a single fuel injection to multiple smaller injections. There are many open questions on the physical processes of the ignition, combustion an

Erlotinib inhibits epithelial growth factor receptor (EGFR) kinase activity and is used to treat non-small cell lung cancer (NSCLC). Despite its high efficacy, recurrence can occur in patients who become resistant to the drug. To address the underlying mechanism of Erlotinib resistance, we investigated additional mechanisms related to mode-of-drug-action, by multiple protein-binding interactions,

The urban expansion currently under development around the two materials science facilities MAX IV and European Spallation Source in Lund, Sweden, surrounds two meticulously designed research facilities steered by global demands. The new urban area, together with the research facilities dedicated to science and the development of knowledge, expands the city of Lund onto high-quality agricultural l

The aethalometer model has shown to offer a fast, inexpensive and robust method for source apportionment. The method relies on aerosol light absorption attribution, mass balance of the total carbon and results in a fraction of unaccounted, residual carbon that has been associated to biogenic carbon due to its presumably non-light absorbing properties. This residual carbon and its relation to trace

Justice is an underlying principle and an important lens in understanding sustainable development goals (SDG). There is a need for analysis and clarification on the underlying principles of justice embedded in the SDGs. Goals such as no poverty (goal 1), zero hunger (goal 2), health and well-being (goal 3), gender equality (goal 5), affordable energy (goal 7), reduced inequalities (goal 10) as wel

Type 2 diabetes, characterized by dysfunction of pancreatic β-cells and insulin resistance in peripheral organs, accounts for more than 90% of all diabetes. Despite current developments of new drugs and strategies to prevent/treat diabetes, there is no ideal therapy targeting all aspects of the disease. Restoration, however, of insulin-producing β-cells, as well as insulin-responsive cells, would