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Direct electron transfer of dehydrogenases for development of 3rd generation biosensors and enzymatic fuel cells

Dehydrogenase based bioelectrocatalysis has been increasingly exploited in recent years in order to develop new bioelectrochemical devices, such as biosensors and biofuel cells, with improved performances. In some cases, dehydrogeases are able to directly exchange electrons with an appropriately designed electrode surface, without the need for an added redox mediator, allowing bioelectrocatalysis

What is the evidence for the use of biologic or biosynthetic meshes in abdominal wall reconstruction?

Introduction: Although many surgeons have adopted the use of biologic and biosynthetic meshes in complex abdominal wall hernia repair, others have questioned the use of these products. Criticism is addressed in several review articles on the poor standard of studies reporting on the use of biologic meshes for different abdominal wall repairs. The aim of this consensus review is to conduct an evide

Expression and prognostic significance of human epidermal growth factor receptors 1, 2 and 3 in oesophageal and gastric adenocarcinomas preneoadjuvant and postneoadjuvant treatment

AIMS: Neoadjuvant treatment has now become the standard of care for oesophageal and gastric cancer. The aim of this study was to investigate the influence of neoadjuvant therapy on the expression of human epidermal growth factor receptor 1 (HER1/EGFR), HER2 and HER3, in oesophageal and gastric adenocarcinoma.METHODS: Immunohistochemical expression of EGFR, HER2 and HER3 was examined and compared i

Integrin αVβ3 can substitute for collagen-binding β1-integrins in vivo to maintain a homeostatic interstitial fluid pressure

New Findings: What is the central question of this study? Collagen-binding β1-integrins function physiologically in cellular control of dermal interstitial fluid pressure (PIF) in vivo and thereby participate in control of extravascular fluid volume. During anaphylaxis, simulated by injection of compound 48/80, integrin αVβ3 takes over this physiological function. Here we addressed the question wh

Transcutaneous oxygen pressure as a predictor for short-term survival in patients with type 2 diabetes and foot ulcers : a comparison with ankle–brachial index and toe blood pressure

Aims: Ankle–brachial index (ABI) is the most commonly used test when diagnosing peripheral vascular disease and is considered a marker for cardiovascular risk. Transcutaneous oxygen pressure (TcPO2), a test associated with microvascular function, has in several studies shown better correlation with diabetic foot ulcer (DFU) healing. Whether a low TcPO2 could be a marker for mortality in the high-r

Disembedded Openness : Inequalities in European Economic Integration at the Sectoral Level

The process of European integration resulted in a marked increase in transnational economic flows, yet regional inequalities along many developmental indicators remain. We analyze the unevenness of European economies with respect to the embedding of export sectors in upstream domestic flows and their dependency on dominant export partners. We use the WIOD dataset of sectoral flows for the period o

Optimal durability in least life cycle cost methods : the case of LED lamps

In the European Union (EU), mandatory durability ecodesign requirements have recently been set for some products, including lighting products; further development of durability standards is also expected in the future. Durability standards can bring environmental and consumer benefits, but the question remains about what optimal durability is. In this paper, the product lifetime aspect of durabili

Self-assembled InN quantum dots on side facets of GaN nanowires

Self-assembled, atomic diffusion controlled growth of InN quantum dots was realized on the side facets of dislocation-free and c-oriented GaN nanowires having a hexagonal cross-section. The nanowires were synthesized by selective area metal organic vapor phase epitaxy. A 3 Å thick InN wetting layer was observed after growth, on top of which the InN quantum dots formed, indicating self-assembly in

Förnyelse - förbistring - försoning : En studie av vitaliseringsrörelser och ekumenisk utveckling på fem sydsvenska orter 1970–2015

Försoning är ett centralt tema i den kristna kyrkan. Denna studie indikerar en diskrepans mellan den teologiska förståelsen av försoning och den praxis som utövas under och efter en konflikt orsakad av olika uppfattningar om församlingens kultur eller identitet, särskilt i relation till vitaliseringsrörelser – förnyelse.I denna studie har etthundra konflikter eller potentiella konflikter som uppstReconciliation is a central theme in the Christian church. This study proceeds from a discrepancy between the theological understanding of reconciliation on the one hand and praxis in dealing with conflicts caused by different opinions about the culture or identity of the church on the other, especially in connection with vitalization (or renewal) movements.In this study, one hundred conflicts or

Norfloxacin degradation by a green carbon black-Ti/SnO2-Sb electrochemical system in saline water

This work aims to degrade a typical antibiotic Norfloxacin (NOR) in saline water with a novel green carbon black based Ti/SnO2-Sb electrochemical catalysis system (TSSC), with Ti/SnO2-Sb as anode (TSSA) and a novel carbon black air diffusion electrode as cathode (CBAC). An electrochemical system with TSSA and a platinum carbon (Pt/C) cathode was used as control (TSSP). The removal ratio, degradati

On the neuronal circuitry mediating l-DOPA-induced dyskinesia

With the advent of rodent models of l-DOPA-induced dyskinesia (LID), a growing literature has linked molecular changes in the striatum to the development and expression of abnormal involuntary movements. Changes in information processing at the striatal level are assumed to impact on the activity of downstream basal ganglia nuclei, which in turn influence brain-wide networks, but very little is ac

On performance of hidden car roof antennas

Hidden antenna solutions for car roofs are of current interest to car manufacturers, to avoid having larger shark-fin based antenna systems to support growing number of wireless services. However, there are only a few studies in the literature on the integration of hidden antennas, particularly in relation to realistic roofs and propagation channels. This paper investigates the performance impact

Volcanic impact on the climate - The stratospheric aerosol load in the period 2006-2015

We present a study on the stratospheric aerosol load during 2006-2015, discuss the influence from volcanism and other sources, and reconstruct an aerosol optical depth (AOD) data set in a resolution of 1° latitudinally and 8 days timewise. The purpose is to include the "entire" stratosphere, from the tropopause to the almost particle-free altitudes of the midstratosphere. A dynamic tropopause of 1

Orientation Insensitive Antenna With Polarization Diversity for Wireless Capsule Endoscope System

An orientation insensitive antenna is proposed for the 2.4-GHz industrial, scientific, and medical band wireless capsule endoscopy system. To achieve the polarization diversity, three orthogonal currents are obtained by bending a dipole. Inversed T matching branch and meander lines are employed to gain better impendence matching and miniaturization. A normal dipole in capsule with single polarizat

Case Studies as Narratives: Reflections Prompted by the Case of Victor, the Wild Child of Aveyron

Drawing on a celebrated case study of a feral child in France, the author argues that there are similarities between stories and case studies as types of narrative and that they are both capable of acting as insightful tools of management inquiry. Both case studies and stories call for narrative imagination to develop meaningful narratives. Serendipity, the accidental discovery of meaning or purpo

Linking, Searching, and Visualizing Entities in Wikipedia

In this paper, we describe a new system to extract, index, search, and visualize entities in Wikipedia. To carry out the entity extraction, we designed a high-performance, multilingual, entity linker and we used a document model to store the resulting linguistic annotations. The entity linker, HEDWIG, extracts the mentions from text usinga string matching Engine and links them toentities with a co