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Long-term Outcome of Cognitive and Emotional Functioning in Young People with ADHD

Den här avhandlingen har som syfte att bidra till att täcka kunskapsluckor om hur tilläggssvårigheter vid attention deficit hyperactivity disorder (ADHD) hos barn förändras och om dessa har ett samband med hur ADHD-problematiken utvecklas under 3 års tid. ADHD är en utvecklingsrelaterad kognitiv funktionsnedsättning som debuterar hos barn och unga, 12 år eller yngre, genom höga nivåer av ouppmärksClarification on how cognitive, executive and emotional functioning contribute to symptom reduction or improved function in childhood attention deficit hyperactivity disorder (ADHD) is needed to find additional treatment methods. The clinical utility of continuous performance test (CPT) (Conners’ CPT-II, QbTest) to complement rating scales in diagnostic assessments and treatment evaluations (QbTes

Structure-activity relationships for analogues of (Z)-5-decenyl acetate, a sex pheromone component of the turnip moth, Agrotis segetum : Synthesis and conformational analysis

Structure-activity relationships for 28 analogues of (Z)-5-decenyl acetate, a sex pheromone component of the turnip moth Agrotis segetum, have been studied.Synthesis and conformational analysis of chain-elongated, chain-shortened, alkyne, alkenyne, diene and cyclic analogues, and configurational isomers are presented.A conformational-energy model for the interaction of a pheromone component with i

Neonatal hyperglycaemia is associated with worse neurodevelopmental outcomes in extremely preterm infants

Objective: To assess the associations between neonatal hyperglycaemia and insulin treatment, versus long-Term neurodevelopmental outcomes in children born extremely preterm. Design and setting: Observational national cohort study (Extremely Preterm Infants in Sweden Study) using prospectively and retrospectively collected data. Neurodevelopmental assessment was performed at 6.5 years of age. Patie

U-Pb baddeleyite age for the Ottfjället Dyke Swarm, central Scandinavian Caledonides : new constraints on Ediacaran opening of the Iapetus Ocean and glaciations on Baltica

The Ottfjället Dyke Swarm (ODS) is a prominent component of the Ediacaran mafic magmatism associated with opening of the Iapetus ocean, and hosted in the Särv Nappe, Middle Allochthon of the Scandinavian Caledonides. A U-Pb baddeleyite age of 596.3 ± 1.5 Ma for a thick, well preserved, plagioclase-phyric dolerite dyke in Härjedalen, Sweden, dates emplacement of the swarm. The age represents a robu

Activation of endogenous retroviruses during brain development causes an inflammatory response

Endogenous retroviruses (ERVs) make up a large fraction of mammalian genomes and are thought to contribute to human disease, including brain disorders. In the brain, aberrant activation of ERVs is a potential trigger for an inflammatory response, but mechanistic insight into this phenomenon remains lacking. Using CRISPR/Cas9-based gene disruption of the epigenetic co-repressor protein Trim28, we f

IL-2Rβγ signalling in lymphocytes promotes systemic inflammation and reduces plasma cholesterol in atherosclerotic mice

BACKGROUND AND AIMS: The relationship between inflammation and lipid metabolism is complex and bidirectional. Lymphocyte-driven inflammation has been shown to modulate both atherosclerotic plaque development and cholesterol levels, but the mechanisms are incompletely understood.METHODS: The cardiometabolic effects of IL-2Rβγ signalling in atherosclerotic Apoe-/- mice were investigated by treatment

Assessing data‐scarce contaminated groundwater sites surrounding petrochemical industries

A common problem when studying groundwater contamination in low-income countries is that data required for a detailed risk assessment are limited. This study presents a method for assessment of the potential impact of groundwater contamination by total petroleum hydrocarbons (TPH) in a data-scarce region. Groundwater modeling, using the MODFLOW, was used to simulate regional-scale flow pattern. Th

Oil refinery and water pollution in the context of sustainable development : Developing and developed countries

This paper is an attempt to evaluate the impact of the oil refinery industry on water resources worldwide from the point of view of sustainable development (SD). The local laws, reports from the industry and environmental agencies, conditions of the final disposal system were analysed. Key aspects, such as existing approaches for treatment systems, quality of treated wastewater, and ways to assure

Muted multidecadal climate variability in central Europe during cold stadial periods

During the last ice age, the Northern Hemisphere experienced a series of abrupt millennial-scale climatic changes linked to variations in the strength of the Atlantic Meridional Overturning Circulation and sea-ice extent. However, our understanding of their impacts on decadal-scale climate variability in central Europe has been limited by the lack of high-resolution continental archives. Here, we

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Ziel der Arbeit ist es, eine Analyse sozio-technischer Energieszenarien durchzuführen, um herauszufi nden, inwieweit soziologische Dimensionen beziehungsweise Konzepte in diesem enthalten sind und welche dabei am häufi gsten aufgegriff en werden. In der vorliegenden Arbeitist eine qualitati ve Inhaltsanalyse dieser Energieszenarien nach Mayring durchgeführt worden.Dabei bestand der theoreti sche H