Copper is an essential micronutrient and yet is highly toxic to cells at elevated concentrations. P1B-ATPase proteins are critical for this regulation, providing active extrusion across cellular membranes. One unique molecular adaptation of P1B-ATPases compared to other P-type ATPases is the presence of metal-binding domains (MBDs) at the cytosolic termini, which however are poorly characterized w

This paper examines the ways in which carbon majors like Shell may present and identify themselves as ‘green’ alternatives whilst undermining the credibility of climate change science by investigating the construction of these narratives and how they differ between internal (employees) and external (general public) audiences. Focus is paid primarily to their rebranding of the late 1990s, analysing

Detta arbete behandlar frågan om enskildas möjligheter att erhålla allmän rättshjälp vid överprövningen av förvaltningsbeslut. Det övergripande syftet har varit att sätta den svenska rättshjälpen och dess förhållande till förvalt-ningsprocessen i ett komparativt perspektiv. En komparativ metod har därför använts för att undersöka likheterna och skillnaderna mellan den allmänna rättshjälpen i SveriThis paper examens the possibility of obtaining legal aid when appealing against administrative decisions. The overall aim has been to put the Swe-dish legal aid system and its relationship to the administrative procedure in a comparative perspective. A comparative method has therefore been used to examine the similarities and differences between the legal aid systems in Sweden, Finland and Norway

Den tekniska utvecklingen på betalningsmarknaden har resulterat i att bedragare använder alltmer sofistikerade metoder för att lura sina offer på pengar. I Sverige har särskilt bankbedrägerier genom social manipulation ökat de senaste åren. Enligt 5a kap. 1 § betaltjänstlagen bär banken som huvudregel det ekonomiska ansvaret för obehöriga transaktioner. För att bestämmelsen ska vara tillämplig kräTechnological developments in the payment market have resulted in fraudsters using increasingly sophisticated methods to defraud their victims of money. In Sweden, bank fraud through social engineering has increased in recent years. According to Chapter 5a, Section 1 of the Payment Services Act, the bank bears, as a general rule, the financial responsibility for unauthorized transactions. However,

Which linguistic labels we use to name ourselves and others – such as disabled and non-disabled – make a difference regarding how we see ourselves and each other. Such labels may also say something about how we view society and the roles of people in it, as illustrated by the choice between people-first and identity-first labels. In the present study, we use a sample of 56,666 articles published b

Denna studie syftar till att undersöka fenomenet socialt stöd och huruvida det har en inverkan på den upplevda arbetstillfredsställelsen hos kontorsmedarbetare inom den privata sektorn. Studien tar även hänsyn till andra eventuella faktorer som främst lön men även kön. Variablerna mättes genom en webbenkät (N=78) och de statistiska analyserna genomfördes genom korrelationer och multipel regressionThis study aims to examine the phenomenon of social support and whether it relates to the perceived job satisfaction of white collar workers in the private sector. The study also considers other potential influencing factors, salary and gender. The variables were measured through a web-based survey (N=78) and statistical analyses were conducted using correlations and multiple regression. The resul

OBJECTIVE: Glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR) is expressed on CD4(+) effector memory T cells and regulatory T cells; however, its role on these functionally opposing cell types in atherosclerosis is not fully understood.APPROACH AND RESULTS: Low-density lipoprotein receptor-deficient mice (Ldlr(-/-)) were lethally irradiated and reconstituted with e

This paper explores the evolving landscape of regional innovation policy, focusing on the interplay between traditional cluster policies and emerging transformative agendas. Over the past decade, policy initiatives aimed at fostering place-based, collaborative innovation have proliferated. However, questions arise regarding the adequacy of existing policy tools in accommodating newer, transformati

At a geological time-scale, seas rise aloft and mountains crumble. We are currently in the middle of a debate on whether—in order to acknowledge the pervasive and geologically significant traces of human action on the planet—our present era should be labelled the “Anthropocene”, and if so, what would be the cut-off date for the commencement of that era. At the same moment, we are already contempla

Ett icke-lagstadgat undantag från upphovsrätten är det s.k. parodiundantaget som kommit att utläsas ur förarbeten till URL och svensk rättspraxis. Parodier har kommit att betraktas som nya och självständiga verk i svensk rätt och har därför sammankopplats med 4 § andra stycket URL. Pastischer har inte uttryckligen nämnts i äldre svenska förarbeten eller svensk rättspraxis, men har antagits inkludeA non-statutory exception to copyright is the so-called parody exception, which have been inferred from legislative history of the Swedish Act on Copyright in Literary and Artistic Works and Swedish case-law. Parodies have come to be regarded as new and independent works in Swedish law and have therefore been linked to Section 4(2) of the Swedish Act on Copyright in Literary and Artistic Works. It

Zinc and selenium may protect against colorectal cancer (CRC) progression through their anti-oxidative effects. This study examined the independent and combined effect of dietary zinc and selenium intake, and polymorphisms of the oxidative stress-related genes (superoxide dismutase 1, superoxide dismutase 2, glutathione peroxidase, and catalase) on CRC risk in a Chinese case-control study. A total

Anti-tumor effect of dietary flavonoids has been sustained by laboratory experiments, but epidemiological studies with breast cancer risk remained inconsistent and insufficient. This study aimed to investigate the associations between total and subclasses of flavonoid and breast cancer risk among Chinese population. This case-control study recruited 1522 eligible breast cancer cases and 1547 frequ

Introduction: During recent years, the world—including Scandinavia—has experienced significant challenges with shortages of antibiotics. In Scandinavia, phenoxymethylpenicillin is recommended as first-line antibiotic treatment for most acute respiratory tract infections (ARTIs). However, the Scandinavian countries each constitute rather small markets for phenoxymethylpenicillin. The aim of this di

Limited-slip differentials (LSD) are normally placed in high-end and race cars to improve the handling, by reducing the differential speed and balancing the torque between the driving wheels. However, electrical-activated LSD struggles to continuously eliminate the differential speed over extended periods of time. To overcome this, BorgWarner proposed a dual-functional clutch pack, featuring two d

Uppsatsen undersöker bolagsrevisorns externa skadeståndsansvar enligt 29 kap. 1–2 §§ aktiebolagslagen (2005:551). Då det externa ansvaret är fokus för uppsatsen behandlar uppsatsen skyddet för aktieägare och andra tredje män. Normskyddslärans betydelse för det externa skadeståndsansvaret är centralt för uppsatsen. I uppsatsen tillämpas en rättsdogmatisk metod. Metoden tillämpas då uppsatsen ämnar This paper examines the auditor's external liability for damages stated in Chapter 29, Sections 1–2 §§ of the Swedish Companies Act (2005:551). The fact that the focus of this paper is on external liability, it addresses the protection of shareholders and other third parties. The importance of the norm protection doctrine for external liability is central to the study. A legal dogmatic method

Syftet med denna studie var att i en svensk kontext undersöka upplevd arbetstillfredsställelse och dess relation till de psykologiska variablerna: arbetsrelaterad autonomi, occupational self-efficacy och socialt stöd i arbetet. Detta med förhoppningen att bidra till en ökad förståelse av det komplexa begreppet arbetstillfredsställelse. Studien tillämpade en kvantitativ metod i form av en enkätundeThe aim of this study was to examine the relationship between perceived job satisfaction and the psychological variables: job autonomy, occupational self-efficacy and social support at work, in a Swedish context. This with the aspiration of contributing to the understanding of the complex concept of job satisfaction. The study used a quantitative method, with a survey conducted among 143 responden

Denna uppsats undersöker beskattning av dispositionsrätt till egendom som ägs av företag, med särskilt fokus på fåmansföretag. Syftet är att klargöra under vilka omständigheter dispositionsrätten leder till inkomstbeskattning, skillnader mellan beskattning i inkomstslagen tjänst och näringsverksamhet samt hur skattskyldiga kan undvika beskattning. Studien har använt rättsdogmatisk metod för att anThis thesis examines the taxation of the right of disposal of company-owned property, with a particular focus on close companies. The purpose is to clarify the circumstances under which the right of disposal leads to income taxation, the differences in taxation between the categories of income from employment and business income, and how taxpayers can avoid such taxation. A legal dogmatic method h

The effects of dietary vitamin D, Ca and dairy products intakes on colorectal cancer risk remain controversial. The present study investigated the association between these dietary intakes and the risk of colorectal cancer in Guangdong, China. From July 2010 to December 2018, 2380 patients with colorectal cancer and 2389 sex- and age-matched controls were recruited. Dietary intake data were collec

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive hematological neoplasm. Little improvement in survival rates has been achieved over the past few decades. Necroptosis has relationship with certain types of malignancies outcomes. Here, we evaluated the diagnostic ability, prognostic capacity of necroptosis-related genes (NRGs) and the effect of their copy number variations (CNVs) in AML.ME