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Correlations of obstetric anal sphincter injury (OASIS) grade, specific symptoms of anal incontinence, and measurements by endoanal and transperineal ultrasound

Purpose: The aim of the study was to investigate the association between the initial grade of obstetrical anal sphincter injury (OASIS), and Wexner score parameters, with ultrasonographic findings by endoanal ultrasound (EAUS, golden standard) and transperineal ultrasound (TPUS) 6 months post-partum. Methods: Fifty-nine women after primary repair of OASIS were included at Helsingborg Hospital, Swe

Role of the Synthetic B1 Vitamin Sulbutiamine on Health

Sulbutiamine is a thiamine derivative developed in Japan in the mid-60's as a beriberi treatment drug. Since then, different potential applications have been described. For instance, there is some evidence that sulbutiamine can have anti-fatigue, nootropic, and antioxidant effects, which led to its use as a sport supplement (although some authors argue it is actually a masking doping strategy). Mo

'Fighting an uphill battle' : a qualitative study of the challenges encountered by pharmacy workers when providing services to men who have sex with men in Dar es Salaam, Tanzania

BACKGROUND: Previous research suggests that Tanzanian MSM might prefer consulting pharmacies and drugstores, rather than public healthcare services, when in need of STI medicines and treatment. Yet, few studies have explored the experiences of providing services to MSM clients among those working at pharmacies and drugstores and examined what challenges they encounter in providing these services.

Fast food outlets, physical activity facilities, and obesity among adults : a nationwide longitudinal study from Sweden

Background: While neighborhood deprivation is a well-known predictor of obesity, the mechanisms behind this association are unclear and these are important to clarify before designing interventions focusing on modifiable neighborhood environmental factors in order to reduce obesity risk. Objectives: This study examined the longitudinal association between availability of fast-food outlets and phys

Potential biomarkers for early detection of pancreatic ductal adenocarcinoma

Pancreatic cancer has the highest mortality amongst all major organ cancers. Early detection is key to reduce deaths related to pancreatic cancer. However, early detection has been challenged by the lack of non-invasive biomarkers with enough sensitivity and specificity to allow for screening. The gold standard is still carbohydrate antigen (CA 19-9), against which all new biomarkers must be evalu

Uncovering the hidden diversity of litter-decomposition mechanisms in mushroom-forming fungi

Litter decomposing Agaricales play key role in terrestrial carbon cycling, but little is known about their decomposition mechanisms. We assembled datasets of 42 gene families involved in plant-cell-wall decomposition from seven newly sequenced litter decomposers and 35 other Agaricomycotina members, mostly white-rot and brown-rot species. Using sequence similarity and phylogenetics, we split the f

Fire-vegetation interactions during the last 11,000 years in boreal and cold temperate forests of Fennoscandia

The long-term ecological interactions between fire and the composition of dominant trees and shrubs in boreal and cold temperate Fennoscandian forests are still under discussion. We hypothesized that fire-prone taxa should abound during periods and regions characterized by higher fire disturbance, while fire-intolerant taxa should dominate when and where fire activity is low. Biomass burning (BB)

Förändringar i antal och lokal utbredning hos övervintrande sjöfåglar vid den skånska sydkusten under 55 vintrar, 1964–2018

THE SOUTH COAST of Scania, southernmost Sweden, has long been an important wintering and staging area for waterbirds. A large part of the coast was surveyed annually as a part of the international midwinter counts for 55 years (1964–2018). The total number of wintering waterbirds showed an increasing trend but there was much variation between years. Common Goldeneye Bucephala clangula, followed by

Comparison of spleen transcriptomes of two wild rodent species reveals differences in the immune response against Borrelia afzelii

Different host species often differ considerably in susceptibility to a given pathogen, but the causes of such differences are rarely known. The natural hosts of the tick-transmitted bacterium Borrelia afzelii, which is one of causative agents of Lyme borreliosis in humans, include a variety of small mammals like voles and mice. Previous studies have shown that B. afzelii-infected bank voles (Myod

The association between habitual sleep duration and mortality according to sex and age : the Japan Public Health Center-based Prospective Study

BackgroundShort and long sleep durations are associated with mortality outcomes. The association between sleep duration and mortality outcomes may differ according to sex and age.MethodsParticipants of the Japan Public Health Center-based prospective study (JPHC Study) were aged 40-69 years and had completed a detailed questionnaire on lifestyle factors. Sex- and age-stratified analyses on the ass

Proteomic comparison of osteoarthritic and reference human menisci using data-independent acquisition mass spectrometry

Objective: Recent research in knee osteoarthritis (OA) highlights the role of the meniscus in OA pathology. Our aim was to compare the proteomes of medial and lateral menisci from end-stage medial compartment knee OA patients, with reference menisci from knee-healthy deceased donors, using mass spectrometry. Design: Tissue plugs of Ø3 mm were obtained from the posterior horns of the lateral and me

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De Forenede Nationers (FN) anbefaling om at fremme psykisk sundhed udtrykker en international anerkendelse af behovet for et mere flerfagligt fokus på psykisk sundhed frem for at fastholde en entydig medicinsk orientering mod sygdom inden for det psykiske sundhedsområde. Anerkendelsen heraf udgør konteksten for, at psykiatrien, forstået som det medicinske subspeciale, nu befinder sig i en grundlag

A review of drying methods for improving the quality of dried herbs

A large number of herb-drying studies have been conducted in recent decades and several herb-drying techniques have been introduced. However, the quality of commercial dried herbs is still lower than that of fresh herbs. In this paper, studies regarding the effect of drying techniques and pre-drying treatments on the aroma and color of dried herbs are reviewed with the aim of providing an overview