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Läkaren som patient : En beskriven rollkonflikt

Flera studier har på senare år visat att den läkare som själv blir sjuk upplever sig försatt i en särskilt problematisk situation. Ett sätt att öka förståelsen för den sjukdomsdrabbade läkarens upplevda dilemma kan vara att närstudera läkares sjukdomsnarrativ. I denna artikel uttolkas tre skriftliga vittnesmål av läkare med morfinmissbruk, med särskild tonvikt på Michail Bulgakovs semifiktiva nove

Medicinhistoria i Lund : En kort översikt

Lunds historia innehåller många medicinhistoriska händelser. Medicinhistoria som akademisk disciplin är dock inte endast deskriptiv utan även analyserande. Flera institutioner vid Lunds universitet bedriver medicinhistorisk forskning från olika utgångspunkter. Medicinhistoria är ett viktigt ämne för förståelsen av dagens medicin och denna översikt vill visa varför och hur ämnet behandlas vid Lunds

The contact angle of nanofluids as thermophysical property

Droplet volume and temperature affect contact angle significantly. Phase change heat transfer processes of nanofluids – suspensions containing nanometre-sized particles – can only be modelled properly by understanding these effects. The approach proposed here considers the limiting contact angle of a droplet asymptotically approaching zero-volume as a thermophysical property to characterise nanofl

Patientens röst - den patografiska genren i historisk belysning

’Patografi’ är beteckningen på en relativt ung och snabbt växande litterär genre. Syftet med denna artikel är att introducera den patografiska genren och att lämna ett bidrag till förståelsen av dess historiska uppkomst. Tre omvälvningar i skolmedicinen vid 1800-talets slut och 1900-talets början lyfts fram som betydelsefulla för den patografiska genrens framväxt: sanatoriernas tillkomst, stigmati

Heritability and genetic variance of dementia with Lewy bodies

Recent large-scale genetic studies have allowed for the first glimpse of the effects of common genetic variability in dementia with Lewy bodies (DLB), identifying risk variants with appreciable effect sizes. However, it is currently well established that a substantial portion of the genetic heritable component of complex traits is not captured by genome-wide significant SNPs. To overcome this issu

Television gambling advertisements : Extent and content of gambling advertisements with a focus on potential high-risk commercial messages

Background: In problem gambling, recent years have seen an expansion of online gambling in treatment-seeking patients. Television advertising may promote risky gambling, and this study aimed to assess gambling-related advertisements, with respect to potentially risky messages, in a country with high rates of online gambling among treatment seekers, for online casino particularly in treatment-seeki

Gambling habits, gambling norms, and problem gambling in foreign born and native populations in Denmark — A general population survey

Background: Being foreign born, i.e. not born in the reception country or belonging to an ethnic minority, has been described as a risk factor of problem gambling, although research so far has been inconclusive. Also, there is limited knowledge about whether this association is caused by differing gambling norms. The present study aimed to study whether foreign origin is associated with problem ga

Accuracy and precision of the RABBIT technique

One of the most ubiquitous techniques within attosecond science is the so-called reconstruction of attosecond beating by interference of two-photon transitions (RABBIT). Originally proposed for the characterization of attosecond pulses, it has been successfully applied to the accurate determination of time delays in photoemission. Here, we examine in detail, using numerical simulations, the effect

­­­Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1

Complement component C3 is central to the complement system, a humoral effector mechanism of innate immune defense. When activated, C3 covalently binds to target particles, marking them for uptake and clearance by phagocytosis. We now show that C3 also exists within the cytosol where it interacts with ATG16L1, and is therefore involved in the intracellular clearance and recycling of material by ma

Protection of Kidney Function with Human Antioxidation Protein α 1 -Microglobulin in a Mouse 177 Lu-DOTATATE Radiation Therapy Model

Aims: Peptide receptor radionuclide therapy (PRRT) is in clinical use today to treat metastatic neuroendocrine tumors. Infused, radiolabeled, somatostatin analog peptides target tumors that are killed by irradiation damage. The peptides, however, are also retained in kidneys due to glomerular filtration, and the administered doses must be limited to avoid kidney damage. The human radical scavenge

Effect of gas distributor on gas–liquid dispersion and mass transfer characteristics in stirred tank

Aiming at the fact that the function of gas distributor is often neglected in the case of high viscosity conditions, a novel spherical micro-orifice gas distributor was proposed and investigated experimentally in water system and non-Newtonian viscous system, respectively. The comparisons of gas–liquid dispersion and mass transfer performance between novel spherical micro-orifice gas distributor a

Complete Revascularization Versus Culprit Lesion Only in Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Disease : A DANAMI-3–PRIMULTI Cardiac Magnetic Resonance Substudy

Objectives: The aim of this study was to evaluate the effect of fractional flow reserve (FFR)–guided revascularization compared with culprit-only percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) on infarct size, left ventricular (LV), function, LV remodeling, and the presence of nonculprit infarctions. Background: Patients with STEMI with

Prognostic value of lymphocyte-monocyte ratio at diagnosis in Hodgkin lymphoma : A meta-analysis

Background: Prognoses of most adult Hodgkin lymphoma (HL) patients are excellent; most of them can achieve permanent remission that can be considered cured. However, many are under-treated or over-treated by standard modern therapies. An accurate determination of prognosis may allow clinicians to design personalised treatment according to individual risk of disease progression and survival. Lympho

One Precursor but Two Types of Graphene Nanoribbons : On-Surface Transformations of 10,10′-Dichloro-9,9′-bianthryl on Ag(111)

On-surface synthesis has emerged in the last decade as a method to create graphene nanoribbons (GNRs) with atomic precision. The underlying premise of this bottom-up strategy is that precursor molecules undergo a well-defined sequence of inter- and intramolecular reactions, leading to the formation of a single product. As such, the structure of the GNR is encoded in the precursors. However, recent

Exploring telomere length in mother-newborn pairs in relation to exposure to multiple toxic metals and potential modifying effects by nutritional factors

Background: The uterine environment may influence telomere length at birth, which is essential for cellular function, aging, and disease susceptibility over the lifespan. However, little is known about the impact of toxic chemicals on early-life telomeres. Therefore, we assessed the potential impact of multiple toxic metals on relative telomere length (rTL) in the maternal blood, cord blood, and

Implementation of the sectional aerosol module SALSA2.0 into the PALM model system 6.0 : Model development and first evaluation

Urban pedestrian-level air quality is a result of an interplay between turbulent dispersion conditions, background concentrations, and heterogeneous local emissions of air pollutants and their transformation processes. Still, the complexity of these interactions cannot be resolved by the commonly used air quality models. By embedding the sectional aerosol module SALSA2.0 into the large-eddy simula

PCR inhibition mechanisms in forensic DNA analysis

In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. Crime scene samples are heterogeneous and often contain background mat

Simultaneous Growth of Pure Wurtzite and Zinc Blende Nanowires

The opportunity to engineer III-V nanowires in wurtzite and zinc blende crystal structure allows for exploring properties not conventionally available in the bulk form as well as opening the opportunity for use of additional degrees of freedom in device fabrication. However, the fundamental understanding of the nature of polytypism in III-V nanowire growth is still lacking key ingredients to be ab