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Non-alcoholic fatty liver disease is a strong predictor of coronary artery calcification in metabolically healthy subjects : A cross-sectional, population-based study in middle-aged subjects

Objectives This study aims to estimate the relationship between non-alcoholic fatty liver disease (NAFLD) and measures of atherosclerotic cardiovascular disease (ASCVD), and to determine to what extent such relationships are modified by metabolic risk factors. Methods The study was conducted in the population-based Swedish CArdioPulmonary bioImage Study (SCAPIS) pilot cohort (n = 1015, age 50–64 y

Label-free cytometry - Novel sorting parameters and opportunities

The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displaceme

A lipid-based passivation scheme for nanofluidics

Stretching DNA in nanochannels allows for direct, visual studies of genomic DNA at the single molecule level. In order to facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We show long-term passivation of nanochannel surfaces to several relevant reagents and demonstrate that the pe

A DNA prism : Physical principles for optimizing a microfabricated DNA separation device

Recently, we reported a microfabricated "DNA prism" device that continuously sorts large DNA molecules (61 kilobase pair to 209 kb) according to size in 15 seconds. In this paper, we develop models to understand and optimize the device. The device's complicated characteristics are explained poorly by a simple model based on the assumption that DNA molecules are fully stretched. Assuming DNA molecu

Assessing progression in engineering study programs

Swedish engineering education is organised as study programs consisting of intertwined chains of course units. Formal program objectives integrate skills, scientific attitudes and engineering knowledge. However, assessment of learning and educational quality typically focuses outcomes of individual course modules. It is our concern that study programme quality and student progression are hard to e

Young consumers’ valuations of new payment services

Purpose: The purpose of this study is to gain a more in-depth understanding of the factors influencing how young consumers value mobile payment services and to develop a conceptual model that describes this process. Design/methodology/approach: Content analysis combined with interaction analysis was applied to empirical material consisting of nine focus group interviews with a total of 55 young ad

Performance of a Semi-Closed Oxy-Fuel Combustion Combined Cycle (scoc-cc) with an Air Separation Unit (ASU)

The objective of this paper is to evaluate the performance of a semi-closed oxy-fuel combustion combined cycle (SCOC-CC) and its power penalties. The power penalties are associated with CO2 compression and high-pressure oxygen production in the air separation unit (ASU). The paper discusses three different methods for high pressure oxygen (O2) production. Method 1 is producing O2 directly at high

The influence of voice quality and multi-talker babble noise on sentence processing and recall performance in school children using cochlear implant and/or hearing aids

Purpose: This study examines the influence of voice quality and multi-talker babble noise on processing and storage performance in a working memory task performed by children using cochlear implants (CI) and/or hearing aids (HA). Methods: Twenty-three children with a hearing impairment using CI and/or HA participated. Age range was between 6 and 13 years. The Competing Language Processing Task (CL

‘A Witness in My Own Case’ : Victim–Survivors’ Views on the Criminal Justice Process in Iceland

Arguments in favour of strengthening the rights of victim–survivors in the criminal justice process have largely been made within the framework of a human rights perspective and with a view to meeting their procedural needs and minimising their experiences of secondary victimisation. In this article, however, I ask whether the prevalent legal arrangement, whereby victim–survivors are assigned the

Association between vitamin D, antimicrobial peptides and urinary tract infection in infants and young children

Aim: Vitamin D stimulates production of the endogenous antimicrobial peptides cathelicidin and β-defensin-2, which are expressed in the urinary tract. We investigated vitamin D status and levels of cathelicidin and β-defensin-2 and their association with urinary tract infection (UTI). Methods: The study included 120 children under three years of age: 76 children with UTIs and 44 otherwise healthy

Pediatric noncompaction patients with high spatial QRS-T angles are at increased risk for ventricular tachycardia

Introduction: Noncompaction cardiomyopathy (NCCM) patients may develop sustained ventricular arrhythmias (VA). Currently no known electrocardiogram (ECG) parameter has demonstrated predictive value for VA development. The spatial QRS-T angle has demonstrated ability to identify VA in other cardiomyopathy populations. Methods: A total of 39 patients with NCCM, defined by compact to non-compact rati

Foreign Investment in Agricultural Development : The Past of the Present in Zambia

This study grounds a highly charged debate on agriculture in developing countries within economic theory, by establishing a structured analytical framework for considering the potential role of foreign investment in supporting agricultural development. The framework is developed to be time and space neutral, such that it can be utilized in various geographic settings and across different time peri

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Small cell lung cancer (SCLC) is a neuroendocrine tumour that exhibits rapid growth and metastatic spread. Although SCLC represents a prototypically undifferentiated cancer type, thyroid transcription factor-1 (TTF-1, gene symbol NKX2-1), a master regulator for pulmonary epithelial cell differentiation and lung morphogenesis, is strongly upregulated in this aggressive cancer type. The aim of this

Loyalty Work : Emotional interactions of defence lawyers in Swedish courtrooms

Försvarsadvokaters arbete utspelar sig i emotionellt laddade men emotionellt begränsade situationer. Detta är särskilt påtagligt i brottmålsrättegångar. Upprivna klienter, oförutsebara avbrott, skakande bevis, emotionella målsägande, till och med moralisk misstänksamhet förväntas hanteras på ett korrekt och passande sätt. Den här avhandlingen analyserar hur detta görs i en svensk kontext, med specDefence lawyers’ work takes place in emotionally charged, yet emotionally constraining situations. This is particularly evident in criminal trials. Distressed clients, unforeseeable disruptions, disturbing evidence, emotional plaintiffs and even moral suspicions should all be managed in a proper and appropriate manner. Loyalty Work analyses how this is done in the context of Sweden, with specific

Go To Hell : Towards a Gesture-Based Compositional Practice

This paper discusses musical gesture from an understanding of musical perception as embodied and enactive, also drawing specifically on Denis Smalley’s [(2007). Space-form and the acousmatic image. Organised Sound, 12(1), 35–58] analysis of performed space. I will provide examples of how choreographies (performed by musicians, with and without their instruments), new music (for Vietnamese and West