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Annealed Glass Failure Modelling : A Weakest-Link Approach with Statistical Analysis

Glas är ett genomsiktligt material som används i byggnader för att utforma miljöer som är ljusa och upplevs som öppna. Modernt byggnadsglas används i konstruktioner som utsätts för betydande laster jämfört med ett traditionellt fönsterglas. Som exempel kan nämnas trappsteg, balustrader, golv, tak och väggpaneler där glasets geometriska utformning kan vara mer eller mindre komplex. Det finns ett beNovel and increased use of glass in building construction has been made possible, as a result of methods of mass production introduced during the 20th century and advanced computational structural analyses. With modern use of glass structures, a range of demands emerge which need to be addressed in the strength design process. The aim of the thesis work has been to develop experimentally verified

Pregnancies, ventricular arrhythmias, and substrate progression in women with arrhythmogenic right ventricular cardiomyopathy in the Nordic ARVC Registry

AIMS: Women with arrhythmogenic right ventricular cardiomyopathy (ARVC) are at relatively lower risk of ventricular arrhythmias (VAs) than men, but the physical burden associated with pregnancy on VA risk remains insufficiently studied. We aimed to assess the risk of VA in relation to pregnancies in women with ARVC. METHODS AND RESULTS: We included 199 females with definite ARVC (n = 121) and muta

Absorption of blocking activity from human tumor‐bearer sera by staphylococcus aureus, cowan I

Staphylococcus aureus, strain Cowan I, contains a cell‐wall substance, protein A, which combines with the Fc part of IgG in most mammalian species. It can therefore be used as a solid‐phase immunoabsorbant for elimination of the reacting immunoglobulins. Since it has been shown that Cowan I could absorb out the blocking activity of sera from rats bearing isografts of polyoma‐virus‐induced sarcomas

“The Spirit of 1914” : A Redefinition and a Defense

The received wisdom has long been that people in Europe reacted with great enthusiasm as war was approaching in August, 1914. However, scholars who have investigated the matter have found little evidence of enthusiasm. There was no unique “spirit of 1914,” and people in general were not happy about the prospect of war. This revisionist thesis is now the new orthodoxy and should as such be subject

Soils, sinks, and smallholder farmers: Examining the benefits of biochar energy transitions in Kenya

Besides reducing fuel demands and indoor air pollution, pyrolytic cooking stoves produce a by-product (biochar) that can improve soil fertility and serve as a sink for carbon sequestration. Most smallholder farmers in Africa depend on wood for fuel, suffer from exposure to smoke and soils in their cultivated farms are deteriorating. Biochar (bio-charcoal) production has potentials to reduce energy

Ultrasound Assisted Alkaline Pre‐treatment Efficiently Solubilises Hemicellulose from Oat Hulls

The establishment of sustainable bioeconomies requires the utilization of new renewable biomaterials. One such material currently seen as a waste product is oat hulls. Oat hulls exhibit a great potential for the production of dietary fibres due to their exceptionally large hemicellulose content (35%). Their recalcitrant structure however requires a suitable pre-treatment method to access and proce

Radical trachelectomy

Radical trachelectomy is the cornerstone' of fertility-sparing surgery in patients with early-stage cervical cancer wishing to preserve fertility. Growing evidence has demonstrated the oncologic safety and subsequent favorable pregnancy outcomes in well-selected cases. In the absence of prospective trials, the decision on the appropriate surgical approach (vaginal, open, or minimally invasive surg

The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tau

The core cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers amyloid beta (Aβ42 and Aβ40), total tau, and phosphorylated tau, have been extensively clinically validated, with very high diagnostic performance for AD, including the early phases of the disease. However, between-center differences in pre-analytical procedures may contribute to variability in measurements across laboratories.

Exogenous LL-37 but not homogenates of desquamated oral epithelial cells shows activity against Streptococcus mutans

Objective: The antimicrobial peptide hCAP18/LL-37 is detected in desquamated epithelial cells of human whole saliva, but the functional importance of this pool of hCAP18/LL-37 is not understood. Here, we assess the impact of homogenates of desquamated oral epithelial cells and exogenous, synthetic LL-37 on two oral bacteria: S. mutans and S. gordonii. Material and methods: Desquamated epithelial c

Southeast Asia’s Roles in Inter-Korean Affairs

Southeast Asia’s significance to the Korean peninsula is growing. South Korea has deepening trade, investment and assistance relationships in the region, while ASEAN’s non-judgmental approach to diplomacy is useful in dealing with Pyongyang. Beyond hosting summits between American and North Korean leaders, Southeast Asia is in a position to mediate North Korea’s greater international engagement an

Perinatal inflammation relates to early respiratory morbidity and lung function at 12 years of age in children born very preterm

Aim: Very preterm birth may be associated with lung function impairment later in life. It is not known if this is caused by prematurity per se or by associated perinatal events, such as maternal–foetal inflammation and severity of early neonatal lung disease. We assessed these factors in a prospective cohort of very preterm infants followed from birth to middle school age. Methods: In 71 infants w

Detection of Non-Small Lung Cell Carcinoma-Associated Genetic Alterations Using a NanoString Gene Expression Platform Approach

In non-small cell lung cancer (NSCLC), mutation detection and fusion gene status are treatment predictive and, hence, key factors in clinical management. Lately, alternate splicing variants of MET have gained focus as NSCLC tumors harboring a MET exon 14 skipping event have proven sensitive toward targeted therapy. Reliable methods for detection of genetic alterations in NSCLC have proven to be of

Early anterior cruciate ligament reconstruction does not affect 5 year change in knee cartilage thickness : secondary analysis of a randomized clinical trial

Objective: To compare 5-year change in femorotibial cartilage thickness in 121 young, active adults with an acute anterior cruciate ligament (ACL) tear randomized to a strategy of structured rehabilitation plus early ACL reconstruction (ACLR) or structured rehabilitation plus optional delayed ACLR. Design: 62 patients were randomized to early ACLR, 59 to optional delayed ACLR. Magnetic resonance i

Lovers of the Rose : Islamic Affect and the Politics of Commemoration in Turkish Museal Display

This chapter explores Hilye-i Şerif, the calligraphic description of the Prophet Muhammad—and its significance in current Turkish politics. With roots in Ottoman literature, art and Prophet devotion, this genre is currently witnessing a striking artistic innovativeness. Under the theme of Aşk-ı Nebi (Love for the Prophet), several public exhibitions have been organised within recent, state-run mevThis chapter explores Turkish museal display as an arena for memory-cultural Islamisation, extending beyond the walls of museums. It probes museums as spaces for exhibiting nationalism, and the burgeoning interest in religion and affect within a new museology. It discusses how Turkish expositions have appropriated aspects of such a new museology in restorative-commemorative expositions of the Otto