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The European Directive 2008/96/CE on Road Infrastructures Safety Management gives great emphasis to road Safety Inspections SI as tool for safety management of existing roads. In this framework, development of surrogate measures of safety derived from data collected during safety inspections can provide a source of information for risk assessment. Furthermore, SIs derived information seems to be p

Experiments with low-energy kaons at the DAΦNE Collider

The investigations of light kaonic atoms offer the unique opportunity to perform experiments equivalent to scattering at vanishing relative energies, being their atomic binding energies in the keV range. This allows the determination of the hadron-nucleus interaction at threshold without the need of an extrapolation to zero relative energy. The energy shift and broadening of the lowest-lying state

Endolymphatic hydrops induced by different mechanisms responds differentially to spironolactone : a rationale for understanding the diversity of treatment responses in hydropic inner ear disease

Background: The exact pathophysiological mechanism(s) underlying endolymphatic hydrops (EH) remain elusive. We have previously shown that chronic administration of vasopressin and inhibitors of the cAMP/cGMP degrading enzymes (PDE3, PDE4, PDE5) results in the development of EH to mice. Aims/objectives: Evaluate the ability of spironolactone, an aldosterone antagonist, to prevent EH, when induced b

How to interpret differing cerebral blood flow patterns estimated with 99tcm-hmpao and 99tcm-ecd spet in a healthy population

Two radiopharmaceuticals, 99Tcm-hexamethyl propylene amine oxime (99Tcm-HMPAO) and 99Tcm-ethyl cysteinate dimer (99Tcm-ECD), are currently used to determine cerebral blood flow. 99Tcm-ECD is, by virtue of its greater stability, superceding 99Tcm-HMPAO for routine examinations. Since the clinical assessment of 99Tcm-ECD images is usually based on experience with 99Tcm-HMPAO, we used both radiopharm

No increase in fracture incidence in patients treated for thyrotoxicosis in Malmo during 1970-74. A 20-year population-based follow-up

Objectives. To study whether there is an increased fracture incidence following thyrotoxicosis. Design. A case-control study. Setting. Malmo University Hospital, Malmo, Sweden. Subjects: All patients (n = 333) from the population of Malmo who were treated for thyrotoxicosis for the first time during the 5-year period 1970-74. A total of 618 controls were selected from the local municipality regist

An enzyme-linked molecularly imprinted sorbent assay

Based on a molecularly imprinted polymer, a competitive binding assay analogous to competitive enzyme immunoassay has been developed. The assay is specific for the herbicide 2,4-dichlorophenoxyacetic acid and uses, for the first time, an enzyme-labelled conjugate as a tracer. The label tobacco peroxidase allowed for colorimetric and chemiluminescence detection. The molecularly imprinted polymer wa

Molecularly imprinted monodisperse microspheres for competitive radioassay

In the present study, molecularly imprinted affinity sorbents against theophylline and 17β-estradiol are synthesised via precipitation polymerisation, a synthetic method that yields monodisperse, spherical polymer particles in the micronscale range, quickly, cleanly and in good yield. The specific binding sites that are created during the imprinting process are analysed via radioligand binding ana

Molecularly Imprinted Polymeric Adsorbents for Byproduct Removal

In this study, both diastereo- and enantioselective adsorbents for a dipeptide derivative were prepared using a molecular imprinting technique. The diastereo- and enantioisomers for the dipeptide derivative N-(benzyloxy-carbonyl)aspartylphenylalanine methyl ester (ZAPM), in addition to the α- and β-isomers, were chosen as test compounds for the investigation of the imprinting effect The close simi

Impacts of Climate Change on Surface Hydrology in the Source Region of the Yellow River

The source region of the Yellow River contributes about 35% of the total water yield in the Yellow River basin playing an important role for meeting the downstream water resources requirements. Hydroclimatic trend and periodicity during the last 50 years were investigated to identify significant changes in time and space over the study area. Results showed that mean annual temperature increased fo

Demographic histories of four spruce (Picea) species of the Qinghai-Tibetan Plateau and neighboring areas inferred from multiple nuclear loci

Nucleotide variation at 12-16 nuclear loci was studied in three spruce species from the Qinghai-Tibetan Plateau (QTP), Picea likiangensis, P. wilsonii, and P. purpurea, and one species from the Tian Shan mountain range, P. schrenkiana. Silent nucleotide diversity was limited in P. schrenkiana and high in the three species from the QTP, with values higher than in boreal spruce species, despite thei

Immigrant Youths with Disabilities and Caregivers from the Middle-East—Challenges and Needs During Transition to Adulthood

Background: Recent years of research have increased the knowledge about how to support the transition to adulthood for youths with disabilities. In today’s multi-cultural societies knowledge about transitioning immigrant youths and their caregivers is still needed.Objective: To describe the expectations and needs of immigrant youths with disabilities residing in Sweden during their transition into

Fishing villages fearing seals

The current presence of three species of seals along the Baltic coast; the grey seal (Halichoerus grupys), the harbor seal (Phoca vitulina) and the ringed seal (Pusa hispida) is a result of successful conservation management. However, seals cause severe economic losses to small-scale fisheries and are considered to threaten traditional fishing communities and thereby cultural values, tourism, and

A local Monte Carlo framework for coherent QCD parton energy loss

Monte Carlo (MC) simulations are the standard tool for describing jet-like multi-particle final states. To apply them to the simulation of medium-modified jets in heavy ion collisions, a probabilistic implementation of medium-induced quantum interference effects is needed. Here, we analyze in detail how the quantum interference effects included in the Baier-Dokshitzer-Mueller-Peigné-Schiff–Zakharo

Standard Model Physics at the HL-LHC and HE-LHC

The successful operation of the Large Hadron Collider (LHC) and the excellent performance of the ATLAS, CMS, LHCb and ALICE detectors in Run-1 and Run-2 with pp collisions at center-of-mass energies of 7, 8 and 13 TeV as well as the giant leap in precision calculations and modeling of fundamental interactions at hadron colliders have allowed an extraordinary breadth of physics studies including pr