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Inventory control in environments with short lead times

Methods currently used for inventory control in industry are with few exceptions developed more than forty years ago. This is for instance the case with methods like reorder point sys-tems, cover-time planning and material requirements planning (MRP). Lead times at that time were typically several weeks and months and order quantities covered typically de-mand over several months. Since then both

Oscillator-strengths For Resonance Transitions In Neutral Selenium and Tellurium Derived From Time-resolved Laser Spectroscopy

We have measured radiative lifetimes for selenium and tellurium resonance levels by using short pulse laser excitation in differentially heated resonance cells. We obtained tau(3S1 Se I) = 2.9(5) ns and tau(3S1 Te I) = 3.1(5) ns, which together with branching ratio values given by Ubelis and Berzinsh yield the absorption oscillator strength f(abs)(Se I, 196.0 nm) = 0.074(16) and f(abs)(Te I, 214.3

Physical limitations on the scattering of electromagnetic vector spherical waves

Understanding the interaction between electromagnetic waves and matter is vital in applications ranging from classical optics to antenna theory. This paper derives physical limitations on the scattering of electromagnetic vector spherical waves. The assumptions made are that the heterogeneous scatterer is passive, and has constitutive relations which are on convolution form in the time domain and

Neuropathology in transplants in Parkinson's disease: Implications for disease pathogenesis and the future of cell therapy.

Neural transplantation is over a century old, but the modern era encompasses only the last 30-40 years. For most of this time period, research has focused on reversing disability engendered by neurologic disease and brain damage. Only recently was it recognized that the underlying neurological disease itself might negatively impact the grafted neurons. We have found that a subset of neurons within

Dairy products and plasma cholesterol levels.

Cholesterol synthesized in the body or ingested is an essential lipid component for human survival from our earliest life. Newborns ingest about 3-4 times the amount per body weight through mother's milk compared to the dietary intake of adults. A birth level of 1.7 mmol/L plasma total cholesterol will increase to 4-4.5 mmol/L during the nursing period and continue to increase from adulthood aroun

Serum Response Factor Controls CYLD Expression via MAPK Signaling Pathway.

Tumor suppressor gene CYLD is a deubiquitinating enzyme which negatively regulates various signaling pathways by removing the lysine 63-linked polyubiquitin chains from several specific substrates. Loss of CYLD in different types of tumors leads to either cell survival or proliferation. In this study we demonstrate that lack of CYLD expression in CYLD-/- MEFs increases proliferation rate of these

Factors related to outcome of neuroischemic/ischemic foot ulcer in diabetic patients.

OBJECTIVES: Peripheral vascular disease (PVD) is an important limiting factor for healing in neuroischemic or ischemic diabetic foot ulcer. The purpose of this study was to identify factors related to healing in patients with diabetes with foot ulcers and severe PVD. METHODS: Patients with diabetes with a foot ulcer, consecutively presenting at a multidisciplinary foot center with a systolic toe p

The Six-Item CTS Symptoms Scale and Palmar Pain Scale in Carpal Tunnel Syndrome.

To evaluate measurement properties of 2 brief outcome measures for carpal tunnel syndrome: the 6-item carpal tunnel symptoms scale (CTS-6) and the 2-item palmar pain scale (measuring severity of pain in the scar/palm and pain-related activity limitation). Our hypothesis was that the CTS-6 is responsive to change in symptoms after surgical treatment and the pain scale is a valid measure of surgery-

Galectins structure and function--a synopsis

The 20 or so galectins expected to be found in man, and their many possible functional effects promise a rich and fruitful research field in the future. At present, the biomedically most promising areas for use of galectins or their ligands are in inflammation, immunity, and cancer. Many good stories can be formulated, but the field lacks the cohesion of knowing basic galectin function. The only b

Public E-services in Sweden: Old Wine in New Bottles?

This paper describes and analyses the political discourse regarding e-government (including terms earlier used) in Sweden in the period from the 1960s until today, drawing on a review of policy documents. It is found that even though both the meanings ascribed to computers, the political visions,and the main arguments have changed considerably over time, the majorplans for action have always remai

Does the Current Constraints in Funding Promote Failure in Humanitarian Supply Chains?

Traditionally, most funding is made available when a disaster occurs. Disaster re-sponse is the implementation of what humanitarian actors did (or didn't do) in pre-paredness for any intervention. Based on a case study of a logistics change in the International Federation of Red Cross Red Crescent Society, this paper discusses how more funding of preparedness can radically improve the speed and qu

Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex.

Haemophilus influenzae protein E (PE) is a 16 kDa adhesin that induces a pro-inflammatory immune response in lung epithelial cells. The active epithelial binding region comprising amino acids PE 84-108 also interferes with complement-mediated bacterial killing by capturing vitronectin (Vn) that prevents complement deposition and formation of the membrane attack complex (MAC). Here, the interaction