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Public Technology Procurement and Innovation

Public Technology Procurement and Innovation studies public technology procurement as an instrument of innovation policy. In the past few years, public technology procurement has been a relatively neglected topic in the theoretical and research literature on the economics of innovation. Similarly, preoccupation with `supply-side' measures has led policy-makers to avoid making very extensive use of

Innovation Policy in the Systems of Innovation Approach: Some Basic Principles.

This contribution aims to deal with innovation policy from the perspective of the systems of innovation approach. The intention is to address basic principles related to national, regional or local as well as sectoral systems of innovation and the policy implications emerging from these. Hence, there will be a very strong emphasis on policy in what follows. However, it is essential, of course, tha

Collaboration in Product Innovation in the East Gothia Regional System of Innovation

The focus of this study is on product innovations done by firms (establishments) and the collaborations they enter into with other firms and organizations in carrying out this activity. The theoretical framework combines innovation theories with the literature on regional innovation systems, industrial districts/clusters and knowledge-based economies. Empirically we have investigated the frequency

Functional procurement for innovation, welfare and the environment: A mission-oriented approach

Public procurement represents a very large share of most economies worldwide. Besides its direct purchasing power, public procurement has an enormous potential to become one of the most important mission-oriented policy instruments in the context of the Sustainable Development Goals. The paper argues that the key to achieve more innovations when pursuing public procurement is to describe problems

Protektionism och utländska direktinvesteringar i den globala ekonomiska krisen

There are signs of increasing protectionism in the world. Foreign direct investment regimes are in many countries gradually shifting away from the past policies of providing incentives to attract foreign multinational firms. Instead, various new regulations are implemented to provide the ability of host country to stop foreign acquisitions of domestic firms. This article examines the development o

Mass Spectrometry-Based Protein Biomarker Discovery in Pancreatic Cancer

Background: Pancreatic cancer has the lowest survival rate among all the major cancer types. Although recent decades have seen advances in diagnostic imaging, surgical techniques, perioperative care and oncological treatment, this has not been translated into major improvements in clinical outcome. The 5-year survival rate remains less than 10% for all stages. One important unmet clinical need is

The EEG, frequency bands during perception and mental rotation of two- and three-dimensional objects

The EEG spectral power in 4 frequency ranges (8-13, 15-25, 25-35, and 35-45 Hz) was studied during mental rotation of two- and three-dimensional objects. Only those EEG segments were analyzed which corresponded to the tasks with similar time of solving. The EEG spectral power of the alpha range was higher under control conditions than during task solving. The spectral power in the range of 15-45 H

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The stages of mental rotation of complicated three-dimensional figures were studied using the intracortical interaction mapping. The role of the parietal areas in the mental rotation was shown. The frontal, central and the right temporal areas are involved in the prerotation setup. Both frontal areas and the left temporo-parieto-occipital areas participate in decision making and verbal response. I

Anti-angiogenic action of leukotriene-C4 induced 15-hydroxyprostaglandin dehydrogenase in colon cancer cells is a TNF-α dependent phenomenon

Introduction: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Cyclooxygenase-2 (COX-2), which plays a key role in the biosynthesis of prostaglandin E2 (PGE2), is often up-regulated in CRC and in other types of cancer. PGE2 induces angiogenesis and tumor cell survival, proliferation and migration. The tumor suppressor 15-hydroxyprostaglandin dehydrogenase (1

Low Temperature Waste Heat Recovery in Internal Combustion Engines

Over the past few decades, the automotive industry has increasingly looked towards increasing the efficiency of the internal combustion engine to meet more stringent emission norms and as a measure to meet demands for improved air quality in cities. One method to improve the internal combustion engine efficiency is to recover some of the energy lost to the coolant and the exhaust using a secondary

Gene expression of breast cancer related genes in circulating tumour cells (CTCs) from patients with metastatic breast cancer

Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal i

Attention and multisensory integration of emotions in schizophrenia

The impairment of multisensory integration in schizophrenia is often explained by deficits of attentional selection. Emotion perception, however, does not always depend on attention because affective stimuli can capture attention automatically. In our study, we specify the role of attention in the multisensory perception of emotional stimuli in schizophrenia. We evaluated attention by interference

Different time courses of Stroop and Garner effects in perception - An Event-Related Potentials Study

Visual integration between target and irrelevant features leads to effects of irrelevant feature congruency (Stroop) or variation (Garner) on target classification performance. Presenting closed geometrical shapes as stimuli, we obtained Stroop and Garner effects of one part of their contour on another, in response times and error rates. The correlates of these effects in brain activity were obser

Anticipated action consequences as a nexus between action and perception : Evidence from event-related potentials

We used high-density event-related potentials (ERP) in a modified flanker paradigm to study the role of anticipated action consequences in action planning and the role of anticipation in the perception of action consequences. Prior to the experiment, participants were trained to classify target letters in a four-alternative forced-choice task; another letter was presented as an effect following ea

Phase synchronization analysis of EEG during attentional blink

The attentional blink (AB) phenomenon occurs when perceivers must report two targets embedded in a sequence of distracters; if the first target precedes the second by 200-600 msec, the second one is often missed. We investigated AB by measuring dynamic cross-lag phase synchronization for 565 electrode pairs in 40-Hz-range EEG. Phase synchrony, on average, was higher in experimental conditions, whe