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Is tourist walkability and well-being different?

Despite the environmental and health importance of tourist walking, specific research on walking and tourism is limited, with walking in leisure and work contexts often being used as a proxy. To fill this gap, this study identifies the effects of perception of air quality and mitigating climate change on attachment to walking relevant to walkable places and subjective well-being, along with compar

Categorisations Impeding and Supporting Universal Design

*Introduction* The adoption of Universal Design in European countries introduces a demand for and ex-pectations of a culture which supports equality and non-stigmatisation, treasuring diversi-ty and striving towards a society for all. *Background*Universal Design comes with a set of values, which create tensions between established practices based on “persons with disabilities” as a distinct, sepa*Introduction* The adoption of Universal Design in European countries introduces a demand for and ex-pectations of a culture which supports equality and non-stigmatisation, treasuring diversi-ty and striving towards a society for all. *Background*Universal Design comes with a set of values, which create tensions between established practices based on “persons with disabilities” as a distinct, sepa

The dis/ablement of bodies in semiotic landscapes – a citizen science approach

Much of our built environment is constructed to accommodate ‘normate’ (Garland-Thomson 1996; Hamraie 2017) bodies. This fact may remain invisible to normate users of public space, much as the ordering of human interaction through categorisation is often invisible (Bowker & Star 1999). Reading semiotic landscapes through the dis/abling (Campbell 1999) of bodies that (attempt to) move through thMuch of our built environment is constructed to accommodate ‘normate’ (Garland-Thomson 1996; Hamraie 2017) bodies. This fact may remain invisible to normate users of public space, much as the ordering of human interaction through categorisation is often invisible (Bowker & Star 1999). Reading semiotic landscapes through the dis/abling (Campbell 1999) of bodies that (attempt to) move through th

Recognizing diversity within everyone’s lived experience: Strengthening the theoretical foundations of Universal Design

Recognizing diversity within everyone’s lived experience:Strengthening the theoretical foundations of Universal DesignThis paper situates Universal Design (UD) within the framework ofsocial justice theory, drawing Honneth’s conceptualisation of socialjustice as mutual recognition. It takes as a starting point theperspective that UD requires a robust theorisation and rationale tosupport implementat

Critical Scenario Identification for Testing of Autonomous Driving Systems

Background: Autonomous systems have received considerable attention from academia and are adopted by various industrial domains, such as automotive, avionics, etc. As many of them are considered safety-critical, testing is indispensable to verify their reliability and safety. However, there is no common standard for testing autonomous systems efficiently and effectively. Thus new approaches for te

Modern technology against falls – A description of the MoTFall project

To meet future challenges from an older and physically less active population innovative solutions are needed. Modern Technology against Falls (MoTFall) aims to prevent falls, increase physical activity and improve self-rated health among older people by means of an information and communication technology based system. The project has developed technology-based solutions, focusing on person-centr

Sustainability science must challenge common sense : A response to Bodin (2021)

In this comment, we respond to the claim of (Bodin, Sustain Sci 16: 2151–2155, 2021) that sustainability science, as a research community, has begun to “lean to the left” in a problematic manner. On one hand, we remain unconvinced by the examples cited as indications for this tendency, and argue for caution in making such judgements. On the other hand, we hold that that there may be reasons for se

Sibling Alcohol Use Disorder Is Associated With Increased Risk for Suicide Attempt

The association between having a sibling diagnosed with alcohol use disorder (AUD) and risk for suicide attempt may be attributable to shared genetic liability between AUD and suicidal behavior, effects of environmental exposure to a sibling’s AUD, or both. To distinguish between these alternatives, we conducted a series of Cox regression models using data derived from Swedish population-based reg

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a protein of critical importance for lineage specification and survival of B-lymphoid progenitors. Here, we report that impaired EBF1 function in mouse B

Search for AL amyloidosis risk factors using Mendelian randomization

In amyloid light chain (AL) amyloidosis, amyloid fibrils derived from immunoglobulin light chain are deposited in many organs, interfering with their function. The etiology of AL amyloidosis is poorly understood. Summary data from genome-wide association studies (GWASs) of multiple phenotypes can be exploited by Mendelian randomization (MR) methodology to search for factors influencingALamyloidosi

Healthy versus Inflamed Lung Environments Differentially Effect MSCs

Background: Despite increased interest in MSC-based cell therapies for the acute respiratory distress syndrome (ARDS), clinical investigations have not yet been successful and understanding of the potential in vivo mechanisms of MSC actions in ARDS remain limited. ARDS is driven by an acute severe innate immune dysregulation, often characterized by inflammation, coagulation, and cell injury. How t

Total cholesterol/HDL-C ratio versus non-HDL-C as predictors for ischemic heart disease : a 17-year follow-up study of women in southern Sweden

Background: A distorted blood lipid profile is an important risk factor for ischemic heart disease (IHD) but the predictive ability of the different lipid measures has rarely been studied. Our aim was to examine and compare, in a large sample of women, the predictive ability of total cholesterol/HDL cholesterol ratio (TC/HDL-C) and non-HDL-C in relation to IHD, adjusted for age, exercise, smoking,

Liberalism in Cambodia : Broken Lineages

This article seeks to recover strands of liberalism in Cambodian politics from the period leading up to Independence onwards. It uses Bell’s (2014) summative conception of the liberal tradition, which understands liberalism contextually as a constructed and contested historical phenomenon. The starting point of the analysis is liberalism from the vantage point of the present: today’s half-hearted