Due to their stable fluorescence, biocompatibility, and amenability to functionalization, fluorescent nanodiamonds (FND) are promising materials for long term cell labeling and tracking. However, transporting them to the cytosol remains a major challenge, due to low internalization efficiencies and endosomal entrapment. Here, nanostraws in combination with low voltage electroporation pulses are us

Denna 'Scandia utblick' diskuterar historiska perspektiv på 1970-talet med utgångspunkt i både svensk och internationell forskning.

The integrin family of adhesion receptors regulates basic functions of cells, and the signals they induce are altered in tumor cells. In this review we discuss how different integrin-dependent signals are generated during cell adhesion and by physical forces acting on cells. We also describe how reactive oxygen species are integral parts of integrin signaling and highlight a few important question

Farmers as volunteers in research could potentially provide a rich resource for exploring sustainable agricultural research questions. To discern emerging patterns in citizen science-based studies on topics with relevance for sustainable agriculture, and reveal salient challenges and opportunities for conducting such studies, we conducted a systematic literature review of 27 peer-reviewed articles

Outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) have improved because of advancements in equipment and techniques. With global collaboration and knowledge sharing, we have identified 7 common principles that are widely accepted as best practices for CTO-PCI. 1. Ischemic symptom improvement is the primary indication for CTO-PCI. 2. Dual coronary angiography and in

We establish support and resistance levels from data in intraday currency exchange market activity based on machine learning methods. Specifically we design two semi-supervised classification neural networks. The first one is based on a variant of the K-means method while the second is based on a Gaussian mixture model with expectation maximisation. Each performs classification from tick data on v

We optimize traffic signal timing sequences for a section of a traffic net- work in order to reduce congestion based on anticipated demand. The system relies on the accuracy of the predicted traffic demand in time and space which is carried out by a neural network. Specifically, we design, train, and evaluate three different neural network models and assert their capability to describe demand from

The marine environment has an important role to play in the change-over to a green economy where the blue fields of the sea can form new and ex- panded cultivation spaces. Over the recent years there has been an increasing interest for seaweed as food in Europe. In this article we follow the sea- weed’s journey into the Swedish cuisine by letting it lead us to different places and actors. Seaweed

Mild behavioral impairment (MBI) is suggested as risk marker for neurodegenerative diseases, such as Alzheimer's disease (AD). Recently, pathologic tau deposition in the brain has been shown closely related to clinical manifestations, such as cognitive deficits. Yet, associations between tau pathology and MBI have rarely been investigated. It is further debated if MBI precedes cognitive deficits i

Definitioner i Socialstyrelsens nya principer för prioritering av intensivvård vid extraordinära förhållanden står i skarp kontrast till principer i prioriteringsplattformen.

The Nordic countries are often considered as remarkably exceptional in terms of the proenvironmental behavior of their citizens and also as forerunners in environmental policies. However, very few empirical studies have been done at the aggregated level about how the Nordics compare to other countries. The article addresses this knowledge gap and analyzes the Nordic region in terms of willingness

The Hemse Group is one of the least understood stratigraphic units of the Silurian sequence of Gotland, Sweden. New results from airborne transient electromagnetic (ATEM) measurements in combination with previously published data from field studies and geophysical investigations shed new light on carbonate platform development during the early- to mid-Ludlow Hemse Group. ATEM reveals a transgressi

Porous frameworks are a term of attracting solid materials assembled by interconnection of molecules and ions. These trendy materials due to high chemical and thermal stability, well-defined pore size and structure, and high effective surface area gained attention to employ as extraction phase in sample pretreatment methods before analytical analysis. Solid-phase microextraction is an important su

Cesium copper halides Cs3Cu2X5 (X = Cl, Br, and I) have attracted much attention for optoelectronic applications because of their self-trap excitons and high photoluminescence quantum yield. Intrinsic point defects play a critical role in the optoelectronic performance of these materials by affecting fundamental properties, such as carrier mobility, lifetime, and recombination rate. In this work,

At Norje Sunnansund, an Early Holocene settlement in southern Sweden, the world’s earliest evidence of fermentation has been interpreted as a method of managing long-term and large-scale food surplus. While an advanced fishery is suggested by the number of recovered fish bones, until now it has not been possible to identify the origin of the fish, or whether and how their seasonal migration was ex

Summary: Vertebral fractures are independent risk factors for vertebral and nonvertebral fractures. Since vertebral fractures are often missed, the relatively new introduction of vertebral fracture assessment (VFA) for imaging of the lateral spine during DXA-measurement of the spine and hips may contribute to detect vertebral fractures. We advocate performing a VFA in all patients with a recent fr