The aim of this study is to investigate the feasibility of using three-directional velocity encoded 3D gradient echo (GE) phase contrast (PC) imaging to assess cerebrospinal fluid (CSF) flow connectivity in the human brain. Five healthy volunteers were scanned using low velocity sensitivity (V-enc = 0.04-0.05 m s(-1)). Flow-time curves were compared to standard 2D PC scans. The 3D data were used t

The European Association of Urology renal cancer guidelines have been updated to recommend nivolumab and cabozantinib over the previous standard of care in patients who have failed one or more lines of VEGF targeted therapy.

Leaf area index (LAI), a measure of canopy density, is a key variable for modelling and understanding primary productivity, and also water use and energy exchange in forest ecosystems. However, LAI varies considerably with phenology and disturbance patterns, so alternative approaches to quantifying stand-level processes should be considered. The carbon isotope composition of soil organic matter (C

People with mobility disability are more often overweight or obese and have lower social capital than people without mobility disability. It is unclear whether having a combination of mobility disability and overweight or obesity furthers negative development of social capital over time.

Photocurrents (PCs) of three p-i-n GaAs solar cells, sample A with InAs quantum dots (QDs) embedded in the depletion region, B with QDs in the n region, and C without QDs, were studied experimentally and theoretically. Above GaAs bandgap, the PC of A is increased, while B is decreased with respect to C, since in A, the QD-induced reflection of hole wave function increases its overlap with electron

We studied the effect in children of an exercise intervention program on fracture rates and skeletal traits. Fractures were registered for 5 years in a population-based prospective controlled exercise intervention study that included children aged 6-9 years at study start, 446 boys and 362 girls in the intervention group and 807 boys and 780 girls in the control group. Intervention subjects receiv

Neuron-specific enolase (NSE) is a widely-used biomarker for prognostication of neurological outcome after cardiac arrest, but the relevance of recommended cutoff values has been questioned due to the lack of a standardized methodology and uncertainties over the influence of temperature management.

Aim: The aim of the study was to reveal young carers' views of design of a web-based support system (WBSS) directed to them and the differences between their views and the views of project representatives (PRs), in a participatory design process. Methods: Eight young people, 17-24 years, were involved in either a work or a test group. The work group participated in video-recorded design meetings w

To promote a healthy and active lifestyle there is a need to increase our knowledge of the level of physical activity (PA) among people with late effects of polio.

Integrated cross-sectoral impact assessments facilitate a comprehensive understanding of interdependencies and potential synergies, conflicts, and trade-offs between sectors under changing conditions. This paper presents a sensitivity analysis of a European integrated assessment model, the CLIMSAVE integrated assessment platform (IAP). The IAP incorporates important cross-sectoral linkages between

Gene set-based analysis methods have recently gained increasing popularity for analysis of microarray data. Several studies have indicated that the results from such methods are more reproducible and more easily interpretable than the results from single gene-based methods. A new method for ranking gene sets with respect to their association with a given predictor or response, using a new framewor

We show that light drives large-amplitude structural changes in thin films of the prototypical ferroelectric PbTiO3 via direct coupling to its intrinsic photovoltaic response. Using time-resolved x-ray scattering to visualize atomic displacements on femtosecond time scales, photoinduced changes in the unit-cell tetragonality are observed. These are driven by the motion of photogenerated free charg

Study Design. Multi-center case-control studyObjective. To investigate the prevalence of back problems in adults with idiopathic scoliosis.Summary of Background Data. Information on the prevalence of back problems in adults with idiopathic scoliosis is scarce, especially in untreated individuals, males and individuals with an age at onset of the scoliosis of less than 10 years.Methods. 1069 indivi

The dietary fibre composition in parsnip has been determined in the soluble and insoluble fraction, together with the physicochemical properties (morphology of particles, particle size distribution (PSD), volume fraction and rheological properties) of the parsnip suspensions at different paste concentration and degree of homogenization. The content of dietary fibre in parsnip was 30.4% of the dry

First-degree atrioventricular (AV) block is a delay within the AV conduction system and is defined as a prolongation of the PR interval beyond the upper limit of what is considered normal (generally 0.20 s). Up until recently, first-degree AV block was considered an entirely benign condition. In fact, some complain that it is a misnomer since there is only delay and no actual block in the AV condu

Calibration of network nodes using only time differences of arrival (TDOA) measurements opens up for interesting applications in wireless ad-hoc sensor networks, e.g. finding the positions of cell phones by only ambient sounds or radio. We present two novel approaches for the problem of self-calibration of network nodes using only TDOA when both receivers and transmitters are unsynchronized. We co

Neural cultures are very useful in neuroscience, providing simpler and better controlled systems than the in vivo situation. Neural tissue contains two main cell types, neurons and glia, and interactions between these are essential for appropriate neuronal development. In neural cultures, glial cells tend to overgrow neurons, limiting the access to neuronal interrogation. There is therefore a pres

A bench scale aerobic submerged membrane bioreactor (ASMBR) was used to treat diluted palm oil mill effluent (POME). For further improving the effluent quality and reduction of bio-fouling, powdered activated carbon (PAC) and zeolite were used as bio-fouling reducers (BM). We compared the performances of ASMBR without BFR (called BFR0) with ASMBR using BFR, namely 2 g/L PAC (BFR1), 4 g/L PAC (BFR2