METTL13 (also known as eEF1A‐KNMT and FEAT) is a dual methyltransferase reported to target the N‐terminus and Lys55 in the eukaryotic translation elongation factor 1 alpha (eEF1A). METTL13‐mediated methylation of eEF1A has functional consequences related to translation dynamics and include altered rate of global protein synthesis and translation of specific codons. Aberrant regulation of METTL13 h

Active galactic nuclei (AGNs) are very powerful galaxies characterized by extremely bright emissions coming from their central massive black holes. Knowing the redshifts of AGNs provides us with an opportunity to determine their distance to investigate important astrophysical problems, such as the evolution of the early stars and their formation, along with the structure of early galaxies. The red

Two-particle Azimuthal correlations are measured with the ALICE apparatus in pp collisions at s=13 TeV to explore strangeness- and multiplicity-related effects in the fragmentation of jets and the transition regime between bulk and hard production, probed with the condition that a strange meson (KS0) or baryon (Λ) with transverse momentum pT> 3 GeV/c is produced. Azimuthal correlations between kao

The influence of personality factors, school achievement goals, academic efficacy, and stressload of serious problems on final grades was studied by giving a questionnaire, The Perceived Stress and Control Assessment Scale, to 915 Swedish high school students. A new measure, Stressload Index, was created by extending the Control-Stress Index. Structural Equation Modeling analysis revealed that the

We study residual polynomials, Rx0,n(e), e⊂ R, x∈ R\ e, which are the degree at most n polynomials with R(x) = 1 that minimize the sup norm on e. New are upper bounds on their norms (that are optimal in some cases) and Szegő–Widom asymptotics under fairly general circumstances. We also discuss several illuminating examples and some results in the complex case such as root asymptotics, a universal

Background Alcohol use disorder (AUD) is clinically heterogeneous. We examine its potential genetic heterogeneity as a function of sex, age, clinical features and mode of ascertainment. Methods In the Swedish population born 1932-1995 (n = 5 829 952), we examined the genetic risk profiles for AUD, major depression (MD), anxiety disorders, bipolar disorder, drug use disorder (DUD), attention defici

PREMIERE: Premiered by Hu Liu during the 2017 China-ASEAN Music Week at the Guangxi University of the Arts on May 28th.NOTE:Imitating the Vivacity of the Human Voice, is a meditation on diversity and the roiling of coexistence. In this piece disparate components from east and west do not suggest a transcendent unification. Rather, rhetorical devices such as “Tiaogong” [跳弓] or “Schleifer” become so

The isolation of mitochondria from potato tubers (Solanum tuberosum L.) is described, but the methodology can easily be adapted to other storage tissues. After homogenization of the tissue, filtration and differential centrifugation, the key step is a Percoll density gradient centrifugation. The Percoll gradient contains two parts: a bottom part containing Percoll in 0.3 M sucrose, and a slightly

Background: To examine the effects of different stages of visual field loss (VFL) from advanced glaucoma on performance in a driving simulator. Methods: Data on performance and safety from a traffic simulator test for 104 participants with withdrawn driver’s licences due to visual field loss from advanced glaucoma were compared with data from 83 individuals without visual deficits in a cross-secti

A new hard-shelled sea turtle (Pan-Cheloniidae) with vestigial soft tissues from the lower Eocene (Ypresian) Fur Formation of Denmark is described and illustrated. The fossil (DK 807) comprises a partial, yet fully articulated carapace (estimated original length ∼50 cm) where the individual bones mostly are preserved in three dimensions, together with an intact sacrum, a consecutive series of arti

Latex coatings are environmentally friendly i.e., they are formed from aqueous polymer dispersions, are cheap to produce and provide exceptional mechanical properties. Therefore, they are ubiquitous and can be found in a wide range of different applications such as paints and varnishes, pressure-sensitive adhesives, textiles, construction materials, paper coatings and inks. However, they also have

We analyse the evolution of mortality rates in Spain by age and gender between 1990 and 2018. We compare municipalities, ranked by socio-economic status (SES) and grouped into bins of similar population size, to study changes not only in levels but also in inequality in mortality across the SES spectrum. We document large decreases in mortality rates throughout the period for all age groups, inclu

Communicative coworkership is an area with great potential for both organizations and communicators. Communicative coworkership is also an area where there is a clear link between the core operation and the communication of the organization. It is fairly easy to demonstrate the value of communicative coworkership for an organisation, for example in terms of crisis aversion, innovation, listening,

The determination of toxic components from fire gases is difficult because the environment is hot, reactions are often temperature dependent, and a lot of soot may be produced. Due to the different properties of the gas components, a different time-consuming procedure for each species has traditionally been used. The use of FTIR (Fourier transform infrared) spectrometers as a continuous monitoring

The amount of various pollutants per year emitted into the atmosphere from fires in Sweden is estimated. The pollutants considered in detail are CO2, CO, HCN, NOx, SO2, HCl, unburned hydrocarbons, and particulate matter. The emission of N2O, aromatic hydrocarbons, dioxins, and heavy metals, is discussed qualitatively. The estimate is based on the number of fires in buildings and vehicles in Sweden

Fire-LCA was invented in response to the need for a more holistic LCA of products containing flame retardants. This chapter describes how to conduct a Fire-LCA, illustrated using three product-based case studies: TV sets, furniture and cables. In the TV-set study a US TV was compared with a European TV, the furniture study compared a European sofa with a UK sofa, while two cables with similar fire

Time-triggered real-time systems achieve deterministic behavior using schedules that are constructed offline, based on scheduling constraints. Their deterministic behavior makes time-triggered systems suitable for usage in safety-critical environments, like avionics. However, this determinism also allows attackers to fine-tune attacks that can be carried out after studying the behavior of the syst