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RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry Number 94201-19-1
Global Value Chains, National Innovation Systems and Economic Development
The purpose of this paper is to examine the hypothesis that increased participation in global value chains (GVCs), such as assembly of imported parts for exports, leads to higher economic growth. The focus is particularly on the extent to which this holds for low-income countries, and the role that capability-building, i.e. development of the national innovation system, plays in the possibility of
Building the evidence base for current systemic treatments for severe, chronic atopic dermatitis : methotrexate vs. azathioprine
XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation
In order to investigate the molecular mechanisms by which the oncogenic mutant KIT/D816V causes transformation of cells, we investigated proteins that selectively bind KIT/D816V, but not wild-type KIT, as potential mediators of transformation. By mass spectrometry several proteins were identified, among them a previously uncharacterized protein denoted XKR5 (XK-related protein 5), which is related
Self-reporting traffic crashes – a systematic literature review
Purpose: A traffic safety analysis that is based on registered crashes often suffers from underreporting, which may result in biased conclusions and lead to misguided crash-prevention strategies. Self-reporting traffic crashes is a complementary method to obtain crash information that is often not available in official databases. By surveying studies from around the world, this paper aims to map t
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The interdisciplinary decision problem : Popperian optimism and Kuhnian pessimism in forestry
Interdisciplinary research in the fields of forestry and sustainability studies often encounters seemingly incompatible ontological assumptions deriving from natural and social sciences. The perceived incompatibilities might emerge from the epistemological and ontological claims of the theories or models directly employed in the interdisciplinary collaboration; or they might be created by other epInterdisciplinary research in the fields of forestry and sustainability studies often encounters seemingly incompatible ontological assumptions deriving from natural and social sciences. The perceived incompatibilities might emerge from the epistemological and ontological claims of the theories or models directly employed in the interdisciplinary collaboration, or they might be created by other ep
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Transcriptional control mechanisms in the wall of the urinary bladder. Myocardin family coactivators and the transcriptomic impact of denervation.
Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. It is well established that a family of regulatory proteins called Myocardin Related Transcription Factors (MRTFs) controls the property of SMCs. SMCs have a number of un
Bacterial outer membrane vesicles induce vitronectin release into the bronchoalveolar space conferring protection from complement-mediated killing
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been studied. This study sought to reveal the involvement of vitronectin in the bronchoalveolar space during pneumonia, to assess the effect of outer membran
Brugada syndrome-associated genetic loci are associated with J-point elevation and an increased risk of cardiac arrest
Introduction: A previous genome-wide association study found three genetic loci, rs9388451, rs10428132, and rs11708996, to increase the risk of Brugada Syndrome (BrS). Since the effect of these loci in the general population is unknown, we aimed to investigate the effect on electrocardiogram (ECG) parameters and outcomes in the general population. Materials and Methods: A cohort of 6,161 individua
Sustainability Impact Assessment of Increased Plastic Recycling and Future Pathways of Plastic Waste Management in Sweden
Plastic is a versatile material that has contributed to numerous product innovations and convenience in everyday life. However, plastic production is growing at an alarming rate, and so has the generation of plastic waste. Unsound waste management results in plastic leakage to the environment with multiple adverse effects to ecosystems. Incineration of plastic waste produces excessive greenhouse g
The use of public procurement to incentivize longer lifetime and remanufacturing of computers
Improving the product lifetime of consumer electronics can provide significant environmental benefits. However, there is a tendency among both professional users and consumers to change products, like computers and mobile phones regularly, and as a result their lifetimes become increasingly shorter. With the rise of the Circular Economy, new policies to promote longer product lifetimes have emerge
Detailed chemical compositions of the wide binary HD 80606/80607 : Revised stellar properties and constraints on planet formation
Differences in the elemental abundances of planet-hosting stars in binary systems can give important clues and constraints about planet formation and evolution. In this study we performed a high-precision, differential elemental abundance analysis of a wide binary system, HD 80606/80607, based on high-resolution spectra with high signal-to-noise ratio obtained with Keck/HIRES. HD 80606 is known to
Search for Higgs boson decays to beyond-the-Standard-Model light bosons in four-lepton events with the ATLAS detector at √s=13 TeV
A search is conducted for a beyond-the-Standard-Model boson using events where a Higgs boson with mass 125 GeV decays to four leptons (ℓ = e or μ). This decay is presumed to occur via an intermediate state which contains one or two on-shell, promptly decaying bosons: H → ZX/XX → 4ℓ, where X is a new vector boson Zd or pseudoscalar a with mass between 1 and 60 GeV. The search uses pp collision data
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Selecting Cutting Data Tests for Cutting Data Modeling Using the Colding Tool Life Model
An analysis on selecting cutting speed, cutting feed and depth of cut when collecting data for the Colding Tool Life Model based on Woxen's Equivalent Chip Thickness was performed to achieve the lowest possible model error. All possible combinations of a large data set were evaluated with regard to model error. This work shows that an increase of ratio between the highest and lowest cutting speed,
Processidentifiering - Projektarbeten hösten 1991
The Gaia-ESO Survey: Evidence of atomic diffusion in M67
Investigating the chemical homogeneity of stars born from the same molecular cloud at virtually the same time is very important for our understanding of the chemical enrichment of the interstellar medium and with it the chemical evolution of the Galaxy. One major cause of inhomogeneities in the abundances of open clusters is stellar evolution of the cluster members. In this work, we investigate va