Inflammatory bowel disease (IBD) is a chronic intestinal disorder, with two main types: Crohn's disease (CD) and ulcerative colitis (UC), whose molecular pathology is not well understood. The majority of IBD-associated SNPs are located in non-coding regions and are hard to characterize since regulatory regions in IBD are not known. Here we profile transcription start sites (TSSs) and enhancers in

Background: Music festivals are known to attract a high proportion of drug users. Methods: Using a survey of 1,772 visitors at the Roskilde Festival in Denmark, we assessed substance use at the festival, the incidence of use of substances among never-users and the incidence of use among lifetime users who had not used a substance in the past 12 months. Results: New onset of tobacco use was reporte

Background: Vacations at international nightlife resorts represent an important but also risky element in the lives of youth in many countries. There is an urgent need for evaluating the role played by bars and nightclubs in producing and reducing risks; this task is important, especially at upcoming nightlife resorts with limited experience in managing young partygoers from other countries. Metho

Portacaval-shunted and sham-operated male rats, fed ad libitum and of similar weight, were studied 2-3 weeks after surgery. At this time serum cholesterol levels did not differ significantly between the two groups, whereas serum triacylglycerols and phospholipids were lower in the shunted group. These animals also showed an increased serum bile acid level and an increased serum estradiol to testos

Ingrid Bosseldal presenterar i den här artikeln den amerikanska psykologen Ross Greene, och reflekterar samtidigt över innebörden av de pedagogiska skillnaderna mellan att tänka "Barn gör rätt om de kan" och "Barn gör rätt om de vill" - och följderna av att välja det ena eller det andra.

We have combined three techniques, High Energy Surface X-Ray Diffraction (HESXRD), Surface Optical Reflectance, and Planar Laser Induced Fluorescence in an operando study of CO oxidation over a Pd(100) catalyst. We show that these techniques provide useful new insights such as the ability to verify that the finite region being probed by techniques such as HESXRD is representative of the sample sur

Purpose: The purpose of this paper is to develop a theory of enterprise risk management (ERM). Design/methodology/approach: The method is to develop a theory for ERM based on identifying the general risk management problems that it is supposed to solve and to apply the principle of deduction based on these premises. Findings: ERM consists of risk governance, which is a set of mechanisms that deals

This teaching case of improved dementia care is mainly targeting employees in the health and care sector, decision-makers or students who study medicine and/or care at universities. The case is available in two versions and has one teaching instruction. Version A1 is adapted to practitioners working in dementia care and is a "clean" description of a success case. Version A2 is targeting students.

A deprioritization of economic growth in policy making in developed nations will need to be part of a global effort to tackle climate change and reembed economy and society into planetary boundaries. The presentation introduces the concept of 'sustainable welfare', which integrates environmental sustainability and social welfare research. Central to this concept is the notion of human needs and ho

Uric acid concentration in human bodily fluids is an important marker for disorders such as gout, pre‐eclamsia or cardiovascular disease. However, currently used methods for its detection either lack sensitivity or require sophisticated, bulky and expensive equipment. In this work, we show that by using surface‐enhanced Raman scattering spectroscopy (SERS) on dried Ag colloidal drops and with 1064

Background: Sociodemographic and spatial disparities in incidence and mortality burden of colorectal cancer (CRC) are important to consider in the implementation of population screening, in order to achieve expected benefit and not increase health inequities. Analytic methods should be adapted to provide rational support for targeted interventions. Methods: CRC incidence rates by tumor stage (I-IV

Since stakeholders today are more aware and informed of various sustainability aspects, they are also becoming more involved and participate in shaping sustainability discourses (see e.g. Golob et al. 2017). It is vital to understand if companies utilise this accentuated commitment towards sustainability aspects by interacting with their stake - holders and involving them in different engagement a