Cell proliferation in the cranial base of A/J mice with 6‐AN‐induced cleft palate
Midsagittal sections of the heads of day 14.5–15.0 control A/J mouse fetuses revealed three areas of rapidly growing cartilage in the cranial base:mesethmoid, presphenoid, and craniopharyngeal. There was a curvature in the presphenoid, which straightened by the time of palatine shelf movement In fetuses of females treated with 6‐aminonicotinamide (6‐AN) on gestation day 13 the presphenoid had not