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Modulation of the Coagulation System During Severe Streptococcal Disease.

Haemostasis is maintained by a tightly regulated coagulation system that comprises platelets, procoagulant proteins, and anticoagulant proteins. During the local and systemic response to bacterial infection, the coagulation system becomes activated, and contributes to the pathophysiological response to infection. The significant human pathogen, Streptococcus pyogenes has multiple strategies to mod

Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

Two novel sites of autophosphorylation were localized to the juxtamembrane segment of the human platelet-derived growth factor (PDGF) beta-receptor. To evaluate the importance of these phosphorylation sites, receptor mutants were made in which Tyr579, Tyr581 or both were replaced with phenylalanine residues; the receptor mutants were stably expressed in porcine aortic endothelial cells. Compared w

Single-stage low-power quadrature RF receiver front-end: the LMV cell

This paper presents the first quadrature RF receiver front-end where, in a single stage, low-noise amplifier (LNA), mixer and voltage-controlled oscillator (VCO) share the same bias current. The new structure exploits the intrinsic mixing functionality of a classical LC tank oscillator providing a compact and low-power solution compatible with low-voltage technologies. A 0.13-mum CMOS prototype ta

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Abstract in Danish Kronikk om trend til sammenkoblede artikler i ph.d. afhandlinger i stedet for monografier, især om kriterier for 'publicerebare' artikler i indhold.

Making Sense of the ‘Agency Programme’ in post-Lisbon Europe: Mapping European Agencies

The institutional landscape of the EU has been transformed through the establishment of agencies and changes brought by the Lisbon Treaty. This article seeks to contribute to our conceptual and empirical understanding of European agencies post-Lisbon. It maps the current European agencies according to timing of establishment, size, functions, governance structures and financial arrangements, and d

Cross-Sectional Area and Strength Differences of Fiberwire, Prolene, and Ticron Sutures.

PURPOSE: Flexor tendons should be repaired with suture material strong enough to permit early motion and small enough for the resulting knot to allow unimpeded tendon glide and healing. This study sought to define differences in cross-sectional area and knotted tensile strength among Fiberwire, Prolene, and Ticron sutures. METHODS: Five strands, each of 3-0 and 4-0 Prolene, Ticron, and Fiberwire s

Cholestatic liver damage is mediated by lymphocyte function antigen-1-dependent recruitment of leukocytes.

BACKGROUND: The role of specific adhesion molecules in cholestasis-induced leukocyte recruitment in the liver is not known. Therefore, the aim of our experimental study was to evaluate the role of lymphocyte function antigen-1 (LFA-1) in cholestatic liver injury. METHODS: C57BL/6 mice underwent bile duct ligation for 12 hours. Mice were pretreated with an anti-LFA-1 antibody or control antibody. S

Fantomaten: The PHANToM för handikappade barn

The PHANToM är en uppfinning från MIT, Massachussets Institute of Technology, som möjliggör kommunikation mellan en människa och en dator med hjälp av känsel. The PHANToM är utvecklad som ett allmänt känselgränssnitt. På CERTEC har vi sett möjligheten att