Sökresultat

Filtyp

Din sökning på "*" gav 528910 sökträffar

Father’s Repeat Migration and Children’s Educational Performance

Repeat migration is a common, but unstudied, pattern of migration. This study examines the potential intergenerational consequences of this behavior. To investigate this, we estimate the effect of fathers’ repeat migration on their children’s grade point averages using population-level register data from Sweden. We find that the children of fathers who repeat migrate have a significantly lower gra

Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface

The remarkably efficient suppression of amyloid fibril formation by the DNAJB6 chaperone is dependent on a set of conserved S/T-residues and an oligomeric structure, features unusual among DNAJ chaperones. We explored the structure of DNAJB6 using a combination of structural methods. Lysine-specific crosslinking mass spectrometry provided distance constraints to select a homology model of the DNAJ

A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons

The brain is composed of hundreds of different neuronal subtypes, which largely retain their identity throughout the lifespan of the organism. The mechanisms governing this stability are not fully understood, partly due to the diversity and limited size of clinically relevant neuronal populations, which constitute a technical challenge for analysis. Here, using a strategy that allows for ChIP-seq

Dimensionless analysis on liquid-liquid flow patterns and scaling law on slug hydrodynamics in cross-junction microchannels

Liquid-liquid flow patterns and slug hydrodynamics were experimentally studied in non-circular glass microchannels with water-butanol, water-toluene, water–oil and water-hexane systems, considering various hydraulic diameters (600 µm, 400 µm, 200 µm), inlet junctions (crossed, T) and aspect ratios (0.5, 1). The aqueous phase was the continuous phase due to the hydrophilic microchannel walls and th

Biocompatible scaffolds based on natural polymers for regenerative medicine

The chitosan and gelatine are commonly used biopolymers for the tissue engineering applications. In the previous methods for the cryogels synthesis, multistep preparation methods using toxic cross-linking agents such as glutaraldehyde are reported. Here, we present a two-step preparation method of gelatin macroporous cryogels and one-step preparation method of chitosan or gelatin cryogels. The phy

Bee diversity in crop fields is influenced by remotely-sensed nesting resources in surrounding permanent grasslands

Landscape heterogeneity is an important driver of biodiversity in agroecosystems. However, the functional heterogeneity of agricultural landscapes, taking into account the different resources that habitat patches can provide to species, has rarely been studied. In this study, we explored the effect of landscape-scale nest availability provided by permanent grasslands on wild bee communities. Wild

Mechanisms of 200 MeV electron radiation in diamond crystal in the axial orientation

The γ-radiation by electrons with the energy of ∼200 MeV in a 100μm-thick diamond crystal has been measured at the MAX-lab experimental facility, when the electrons are incident on the crystal along the 〈100〉 axis. In this case, the intensity of the -radiation with the energy ∼1–2 MeV is approximately 16 times higher than that in amorphous matter of the same thickness. Theoretical calculations bas

Unsaturated ion diffusion in cementitious materials – The effect of slag and silica fume

This paper investigates the moisture dependency of ion diffusion in binary cementitious binders with Portland cement (OPC) in combination with slag or silica fume. Resistivity measurements and calculations with a thermodynamic model, GEMS, were used to assess the unsaturated chloride diffusion coefficient. The results show that the relation between the relative diffusion coefficient and the degree

Simulation of NOM removal by capillary NF : A numerical method for full-scale plant design

The removal of natural organic matter (NOM) from boreal lake water by a novel capillary nanofiltration (NF) membrane was predicted using a computational fluid dynamics (CFD) modelling approach. The 2-dimensional axis-symmetric model was based on a 48 m3/day NF pilot plant operating in cross-flow mode on water containing 8 mg/L total organic carbon (TOC) at fluxes ranging from 10 to 25 L/m2/h and v

Usefulness of a clinical risk score to predict the response to cardiac resynchronization therapy

Background: Almost 1/3 of heart failure patients fail to respond to cardiac resynchronization therapy (CRT). A simple clinical score to predict who these patients are at the moment of referral or at time of implant may be of importance for early optimization of their management. Methods: Observational study. A risk score was derived from factors associated to CRT response. The derivation cohort wa

Midwifery students’ experiences of learning through the use of written reflections – An interview study

In an effort to strengthen midwifery students’ learning process, written reflections during the students’ clinical practice at birth units have been applied. The aim of this study was to examine how students of midwifery experienced the writing of daily reflections on their practice at birthing units. An interview study was carried out using an inductive method with descriptive design. During 2013

Designing an Autonomous Integrated Downstream Sequence From a Batch Separation Process − An Industrial Case Study

This work is a proof of concept of how a sequence of industrial batch separation steps together are used to form an integrated autonomous downstream process. The sequence in this case study consisted of an anion chromatography step, virus inactivation and finally a hydrophobic chromatography step. Moving from batch to integrated separation minimizes hold‐up times, storage tanks, and required equip

Collectivity without plasma in hadronic collisions

We present a microscopic model for collective effects in high multiplicity proton–proton collisions, where multiple partonic subcollisions give rise to a dense system of strings. From lattice calculations we know that QCD strings are transversely extended, and we argue that this should result in a transverse pressure and expansion, similar to the flow in a deconfined plasma. The model is implement

Neural pattern classification tracks transfer-appropriate processing in episodic memory

The transfer-appropriate processing (TAP) account holds that episodic memory depends on the overlap between encoding and retrieval processing (e.g., perceptual or conceptual). In the current study, we employed multivariate pattern analysis (MVPA) of electroencephalography to examine the relevance of spontaneously engaged processing during encoding for later retrieval. Participants encoded word-picThe transfer-appropriate processing (TAP) account holds that episodic memory depends on the overlap between encoding and retrieval processing (e.g., perceptual or conceptual). In the current study, we employed multivariate pattern analysis (MVPA) of electroencephalography to examine the relevance of spontaneously engaged processing during encoding for later retrieval. Participants encoded word-pic

From an information consumer to an information author : a new approach to business intelligence

Self-Service Business Intelligence (SSBI) enables business users, such as executives, managers, analysts, and knowledge workers to build reports on a need-basis to support their decisions and actions toward business success. This suggests that business users are empowered not only to consume information but also to author it. Yet, research on SSBI is mainly concentrated at the industrial level, an

Magnetic Resonance Spectroscopy in Schizophrenia : Evidence for Glutamatergic Dysfunction and Impaired Energy Metabolism

In the past couple of decades, major efforts were made to increase reliability of metabolic assessments by magnetic resonance methods. Magnetic resonance spectroscopy (MRS) has been valuable for providing in vivo evidence and investigating biomarkers in neuropsychiatric disorders, namely schizophrenia. Alterations of glutamate and glutamine levels in brains of schizophrenia patients relative to he