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Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery.

1 Organ culture has been shown to upregulate both endothelin (ET) and 5-hydroxytryptamine 1B/1D (5-HT(1B/1D)) receptors in rat cerebral arteries. The purpose of the present study was to investigate the involvement of protein kinases, especially protein kinases C (PKC) and A (PKA) in this process. 2 The effect of inhibiting protein kinases during organ culture with staurosporine (unspecific protein

HZTool and Rivet: Toolkit and Framework for the Comparison of Simulated Final States and Data at Colliders.

A common problem in particle physics is the requirement to reproduce comparisons between data and theory when the theory is a (general purpose) Monte Carlo simulation and the data are measurements of final state observables in high energy collisions. The complexity of the experiments, the obervables and the models all contribute to making this a highly non-trivial task. We describe an existing lib

The dorsal vagal complex as a site for cocaine- and amphetamine-regulated transcript peptide to suppress gastric emptying.

Cocaine- and amphetamine-regulated transcript-derived peptides (CARTp) and corticotropin-releasing factor (CRF) alter feeding and gastrointestinal function after central administration, and the gastric inhibitory effects are mediated through CRF. We hypothesized that dorsal hindbrain effects of CARTp on gastric emptying are mediated by the vagus nerve and that the dorsal vagal complex (DVC) is a s

A population-based study on the first forty-eight breast cancer patients receiving trastuzumab (Herceptin (R)) on a named patient basis in Sweden

Several studies have presented data on the efficacy and tolerability of trastuzumab within clinical trials. As a minority of patients is included in these trials, we undertook this retrospective study to describe trastuzumab therapy in clinical routine and its tolerability. We reviewed the medical records of the first 48 patients in Sweden who received treatment with trastuzumab on a named patient

Quantification of the Formaldehyde Emissions from Different HCCI Engines Running on a Range of Fuels

In this paper, the formaldehyde emissions from three different types of homogenous charge compression ignition (HCCI) engines are quantified for a range of fuels by means of Fourier Transform Infra Red (FTIR) spectroscopic analysis. The engines types are differentiated in the way the charge is prepared. The characterized engines are; the conventional port fuel injected one, a type that traps resid

Everyday problems in men with prostate cancer. Aspects of micturition, indwelling urinary catheter treathment and sexual life

Popular Abstract in Swedish ”Vardagliga problem hos män med prostata cancer. Upplevelser av problem med att kasta vatten, bära kateter och problem i sexuallivet”. Avhandlingens övergripande syfte var att undersöka förekomsten av vardagliga problem hos män med prostatacancer, problemens relation till livskvalitet, till känsla av sammanhang och relationen mellan dessa faktorer, samt att jämföra medThe aim was to investigate the presence of everyday problems in men with prostate cancer, their relation to health-related quality of life, HRQOL, and sense of coherence, SOC, and to compare with men with benign prostatic hyperplasia, BPH, and a sample from the general population. The aim also was to investigate what nursing care needs there were in men with prostate cancer and how these were met

Threshold stoichiometry for beam induced nitrogen depletion of SiN

Measurements of the stoichiometry of silicon nitride films as a function of the number of incident ions using heavy ion elastic recoil detection (ERD) show that beam-induced nitrogen depletion depends on the projectile species. the beam energy, and the initial stoichiometry. A threshold stoichiometry exists in the range 1.3 > N/Si greater than or equal to 1, below which the films are stable agains

Review of particle physics

This biennial Review summarizes much of Particle Physics Using data from previous editions, plus 2205 new measurements from 667 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons We also summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles All the particle properties and searc

Inter-institutional reproducibility of flow cytometric DNA-analysis in breast carcinomas

In order to study interinstitutional reproducibility of flow cytometric DNA-analysis (DNA-FCM), frozen pieces from 30 consecutive breast carcinomas were analysed by 5 laboratories. Different instruments, preparation and DNA staining methods were used. A concordance in DNA-ploidy status was obtained in 26 of the 30 tumours. The discrepancy can mainly be explained by intratumoural DNA-heterogeneity

Smoking particles enhance endothelin A and endothelin B receptor-mediated contractions by enhancing translation in rat bronchi.

Background Smoking is known to cause chronic inflammatory changes in the bronchi and to contribute to airway hyper-reactivity, such as in bronchial asthma. To study the effect of smoking on the endothelin system in rat airways, bronchial segments were exposed to DMSO-soluble smoking particles (DSP) from cigarette smoke, to nicotine and to DMSO, respectively. Methods Isolated rat bronchial segment

Towards the Integration of Control and Real-Time Scheduling Design

The thesis deals with scheduler and controller co-design for real-time control systems. The overall goal is higher resource utilization and better control performance. One goal is to minimize the performance loss due to jitter and control delays. Another goal is to relax the nominal requirements on hard deadlines and fixed worst-case execution times. A third goal is to provide a co-simulation envi

2,3-butanedione monoxime increases speed of relaxation in single muscle fibres of frog

The effects of 2,3-butanedione monoxime (BDM) on intracellular Ca2+ transient and cross-bridge function were studied in frog single fibres from the anterior tibialis muscle of Rana temporaria (sarcomere length, 2.2 m; temperature, 24 C). The fluorescent dye fluo-3 was used to monitor the intracellular free calcium concentration ([Ca2+i) during isometric contractions. BDM (15 m M) reduced the ampli

108Sn Studied with Intermediate-energy Coulomb Excitation

The unstable neutron-deficient Sn-108 isotope has been studied in inverse kinematics by intermediate-energy Coulomb excitation using the RISING/FRS experimental setup at GSI. This is the highest Z nucleus studied so far with this method. Its reduced transition probability B (E2;0(g.s.)(+)-> 2(1)(+)) has been measured for the first time. The extracted B(E2) value of 0.230(57)e(2) b(2) has been dete

Rapport från Lunds universitets kyrkohistoriska arkiv (LUKA) 1998-2002

Denna rapport i Kyrkohistorisk årsskrift, som jag sedan 2001 redigerar, redovisar LUKA:s utvidgade verksamhet med årliga arrangemang som LUKA-dagen i mars och Arkivens dag i november, skriftutgivning (Bibliotheca Historico-Ecclesiastica Lundensis samt Meddelanden från Kyrkohistoriska arkivet i Lund. Ny följd), nya frågelistor till alla Svenska kyrkans församlingar, till församlingarna i vissa stif