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Kost och konsekvens: Halsbakteriens anpassning till olika miljöer Det är inte helt ovanligt att en normal förkylning övergår i en envis infektion som behöver behandlas med antibiotika. Detta beror på att vissa bakterier som vanligtvis lever fredligt i våra luftvägar plötsligt tar chansen att angripa oss när vårt försvar är som svagast. En sådan bakterieart är icke-typbar Haemophilus influenzae (NNon-typeable Haemophilus influenzae (NTHi) is a commensal with opportunistic tendencies that reside in the human nasopharynx. Since the implementation of the H. influenzae serotype b vaccine, NTHi infection has significantly increased worldwide and is of particular concern to society’s most vulnerable such as young children, elders and immunocompromised individuals. Diseases associated with NTHi a

Structured abstractPurposeThe purpose is to examine how academic researchers perceive the communication dynamics in virtual and hybrid conferences to gain access to communities of knowledge. The paper contributes to the research field of strategic communication.MethodologyUsing a qualitative, interpretive approach, purposive sampling was utilised to recruit a diverse group of researchers from Swed

BACKGROUND: Excessive dietary salt intake is associated with elevated blood pressure and damage to organs including the heart, vasculature, and kidneys. Women are more prone to salt-sensitive hypertension, yet preclinical studies often focus on men.METHODS: To examine sex-specific responses to chronic salt loading, male and female C57Bl6/J mice were fed a high-salt diet (HSD; 8% NaCl) from 7 to 14

Spectral electrical impedance tomography (sEIT) has attracted increasing interest in hydrogeology, biogeosciences, agriculture and environmental studies. However, broad-band sEIT measurements, particularly at frequencies above 50 Hz, have long been challenging due to electromagnetic (EM) coupling effects. Recent advances in instrumentation, data correction and filtering have improved sEIT measurem

Autonomy is central to thinking about democracy and human needs, but the question of how autonomy relates to growth is ambivalent. Is growth necessary to achieve a basic level of autonomy, or is autonomy, in fact, a pre-requisite for post-growth? In this study, we examine this question by focusing on how critical autonomy relates to growth within the domains of democracy, education, and work. Crit

The peak-hour travel demand is the most important operational cost driver for public transport in Sweden. Implementing staggered school starting hours as a measure to spread out the travel demand has proven to be challenging. This study focuses on overcoming barriers to collaboration between public transport authorities, municipalities, and schools concerning school transport planning and school o

Introduction: Neuromelanin containing cell loss, neuroinflammation and synaptic dysfunction are believed to contribute to Parkinson's disease (PD) pathogenesis. [18F]DOPA PET reflects dopamine storage capacity in the putamen, while midbrain off-target retention of [18F]RO948 is hypothesized to reflect neuromelanin. Objectives: To investigate associations between disease duration, cerebrospinal flu

Determining the appropriate duration for traffic conflict observation remains a critical yet unresolved challenge in road safety analysis. Existing approaches lack a quantitative approach to determine adequate sample sizes for general conflict-based applications. This study addresses this gap by proposing an extreme value theory based framework to determine appropriate observation durations, based

This study analyzed daily temperature data from 114 meteorological stations in the Qinling-Daba Mountains from 1980 to 2017, focusing on core zones (CE I ≥ 2274 m, CE II 1321–2274 m) and peripheral zones (PE I 668–1321 m, PE II < 668 m). Using 15 extreme temperature indices computed with RClimDex, we assessed the spatiotemporal patterns, trends, and response to climate warming of extreme temperatu

Cumulate xenoliths from beach boulders in Anaga, Tenerife were analyzed through optical microscopy, scanning electron microscopy (SEM), both EDS and EBSD, and barometric modelling to study the magmatic evolution and volcanic plumbing system of the Anaga massif. Petrographic results indicate crystallization from hydrous basaltic magmas at equilibrium. This was further supported with chemical analy

OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld

PURPOSE: Groin hernia repair is a common procedure in general surgery, and is taught to and performed by surgeons early in their training. The aim of this observational study was to compare hernia repair performance and results of surgical trainees with those of a specialized surgeon, to identify what factors may influence short and long-term outcome, and areas for improvement in surgical training

A central assumption in neuroscience is that learning mechanisms are conserved across species. Eyeblink conditioning, a cornerstone paradigm for studying associative learning and cerebellar function, has been widely used in humans and animal models alike. Yet direct cross-species comparisons remain rare. In this systematic review, we analyzed 484 eyeblink conditioning experiments reported in 271 s

BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial

Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new

BACKGROUND: Drug-coated devices are widely used to reduce restenosis after lower limb revascularisation in patients with peripheral artery disease, but their effect on patient-centred outcomes remains unclear. We assessed the effect of paclitaxel-coated devices on clinically important outcomes in patients with intermittent claudication undergoing infrainguinal endovascular revascularisation.METHOD

OBJECTIVE: Childhood obesity may impact the risk of islet autoimmunity (IA). The trajectory of BMI through childhood resembles the early peak incidence of first-appearing autoantibodies against insulin (IAA-first) but not GAD65 (GADA-first). We studied whether a child's BMI can impact the age-related risk of first-appearing IA phenotypes.RESEARCH DESIGN AND METHODS: We identified 7,724 children at

Bakgrund: Neuropsykiatriska funktionsnedsättningar uppstår oftast tidigt i barndomen, vilket gör tidig identifiering viktig för att stödja hälsosam utveckling. Det saknas ett bredare screeninginstrument för neuropsykiatrisk funktionsnedsättning för barn under två och ett halvt år. SÖK-Observations instrumentet utvecklades för att identifiera atypisk utveckling och autism hos barn vid 8-månaders hä