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Modeling for transboundary water resources planning and allocation: the case of Southern Africa

International water resources agreements for transboundary rivers in southern Africa are generally founded in system analysis models for water planning and allocation. The Water Resources Yield Model (WRYM) developed in South Africa has so far been the only model applied in official joint water resources studies aimed to form water-sharing agreements. The continuous discussion around the model per

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.

Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age with a peak incidence in adolescents and young adults. The treatment of ES relies on a multidisciplinary approach, coupling risk-adapted intensive neoadjuvant and adjuvant chemotherapies with surgery and/or radiotherapy for control of the primary site and possible metastatic disease. The optimization of ES mul

Gastroscopy in pediatric surgery: indications, complications, outcomes, and ethical aspects.

Background. The aim of this study was to map gastroscopies performed at a single tertiary pediatric surgery centre to investigate indications, complications, outcomes, and ethical aspects. Material and Methods. A retrospective study of gastroscopies performed during two time periods (2001-2004 and 2011-2014) was conducted. Data regarding indications, outcomes, and complications of pediatric gastro

An international multicentre study on the allergenic activity of air-oxidized R-limonene.

Background. Limonene is a common fragrance terpene that, in its pure form, is not allergenic or is a very weak allergen. However, limonene autoxidizes on air exposure, and the oxidation products can cause contact allergy. Oxidized R-limonene has previously been patch tested in multicentre studies, giving 2-3% positive patch test reactions in consecutive patients. Objectives. To investigate whether

Men's and women's perspectives on using a powered mobility device: Benefits and societal challenges.

Abstract Objective: To describe how men and women experience their use of powered wheelchairs (PW) and powered scooters (PS) in everyday occupations, in the home and in society at large. Methods: A qualitative research approach with focus-group methodology was used. Four focus groups were created, with men and women as well as PW and PS users in different groups. Applying a descriptive approach, d

Executive Summary: International Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases

A Panel of International Experts was convened by the Infectious Diseases Society of America (IDSA) in collaboration with the European Society for Microbiology and Infectious Diseases (ESCMID) to update the 1999 Uncomplicated Urinary Tract Infection Guidelines by the IDSA. Co-sponsoring organizations include the American Congress of Obstetricians and Gynecologists, American Urological Association,

Hydrosilylation of Styrene on Water-Saturated Si(001)-2 x 1 at Room Temperature

The Si(001)-2 x 1 surface saturated by water is characterized by the passivation of nearly all of the dimerized atoms by H/OH terminations, except isolated dangling bonds, whose areal density is in the range of 1.5 +/- 0.2 x 10(-2) defects per Si atom. Therefore the water-saturated Si(001)-2 x 1 surface presents similarities with the defective H-terminated Si(001)2 x I. surface (presence of monohy

Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand.

Carbohydrate-binding modules (CBMs) are key components of many carbohydrate-modifying enzymes. CBMs affect the activity of these enzymes by modulating bonding and catalysis. To further characterize and study CBM-ligand binding interactions, neutron crystallographic studies of an engineered family 4-type CBM in complex with a branched xyloglucan ligand were conducted. The first neutron crystal stru

Adsorption, desorption, and surface-promoted hydrolysis of glucose-1-phosphate in aqueous goethite (alpha-feooh) suspensions

Adsorption, desorption, and precipitation reactions at environmental interfaces govern the fate of phosphorus in terrestrial and aquatic environments. Typically, a substantial part of the total pool of phosphorus consists of organophosphate, and in this study we have focused on the interactions between glucose-I-phosphate (G I P) and goethite (alpha-FeOOH) particles. The adsorption and surface-pro

Effectiveness of beads for tracking small-scale molecular motor dynamics

Investigations into molecular motor dynamics are increasingly focused on small-scale features of the motor's motion. We define performance measures of a common type of single-molecule motility assay, the bead assay, for its ability to detect such features. Using numerical models, we explore the dependence of assay performance on a number of experimentally controllable parameters, including bead si

Measurements of occupancy levels in multi-family dwellings-Application to demand controlled ventilation

The occupancy level of dwellings is an important parameter to know to determine the energy efficiency, energy use and indoor air quality, especially in low-energy buildings where the user-related energy uses, such as household electricity and domestic hot water heating, are significant parts of the energy balance in a building. For residential buildings, there is a lack of occupancy level data, wh

Measurement of electrons from semileptonic heavy-flavor hadron decays in pp collisions at root s=2.76 TeV

The p(T)-differential production cross section of electrons from semileptonic decays of heavy-flavor hadrons has been measured at midrapidity in proton-proton collisions at root s = 2.76 TeV in the transverse momentum range 0.5 < p(T) < 12 GeV/c with the ALICE detector at the LHC. The analysis was performed using minimum bias events and events triggered by the electromagnetic calorimeter. Predicti

Sea-level changes across the Paleocene-Eocene interval in the Spanish Pyrenees, and their possible relationship with North Atlantic magmatism

The issue of whether major and rapid global sea-level changes existed on a preglacial Earth can be resolved by the detailed study of the Paleocene-Eocene (P-E) interval, where a large and rapid carbon isotope excursion linked to an important global warming event, the Paleocene Eocene Thermal Maximum, allows for high-resolution correlation between terrestrial, coastal and marine settings. Based pri

EuroInf: A Multicenter Comparative Observational Study of Apomorphine and Levodopa Infusion in Parkinson's Disease

Subcutaneous apomorphine infusion (Apo) and intrajejunal levodopa infusion (IJLI) are two treatment options for patients with advanced Parkinson's disease (PD) and refractory motor complications, with varying cost of treatment. There are no multicenter studies comparing the effects of the two strategies. This open-label, prospective, observational, 6-month, multicenter study compared 43 patients o

Parametric study on heat transfer enhancement and pressure drop of an internal blade tip-wall with pin-fin arrays

One way to cool gas turbine tips is to design serpentine passages with 180A degrees turns inside the blades to fully utilize the coolant potential. It is therefore a desire to improve the cooling of the blade tips to ensure a long durability and safe operation. In the present work, a two-pass channel with a 180A degrees turn and various arrays of pin-fins mounted internally on the tip-cap is consi

Fibroblasts Cultured on Nanowires Exhibit Low Motility, Impaired Cell Division, and DNA Damage.

Nanowires are commonly used as tools for interfacing living cells, acting as biomolecule-delivery vectors or electrodes. It is generally assumed that the small size of the nanowires ensures a minimal cellular perturbation, yet the effects of nanowires on cell migration and proliferation remain largely unknown. Fibroblast behaviour on vertical nanowire arrays is investigated, and it is shown that c