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Sport-Related Concussion: Neuroimaging, Biomarker, Vestibular and Neuropsychological Studies

A sport-related concussion (SRC) is caused by a force transmitted to the brain during sports, and may lead to long-term disabilities and neurodegeneration. The underlying pathophysiological mechanisms causing persistent post-concussive symptoms (PPCS) lasting beyond the normal four-week period, have not been established. The aim of this thesis was to investigate mechanisms of persistent symptoms i

The cost-vs.-quality trade-off in make-or-buy decisions

The make-or-buy decision is analyzed in a simple two-task principal-agent model. There is a cost-saving-vs.-quality trade-off in effort provision, both effort and outcome having these two dimensions. The principal faces a dichotomous choice between make/in-house, coming with weak cost-saving incentives for the agent, and buy/outsourcing, coming with strong incentives; the dichotomy is due to an in

Widespread White Matter Abnormalities in Concussed Athletes Detected by 7T Diffusion Magnetic Resonance Imaging

Sports-related concussions may cause white matter injuries and persistent post-concussive symptoms (PPCS). We hypothesized that athletes with PPCS would have neurocognitive impairments and white matter abnormalities that could be revealed by advanced neuroimaging using ultra-high field strength diffusion tensor (DTI) and diffusion kurtosis (DKI) imaging metrics and cerebrospinal fluid (CSF) biomarSports-related concussions may cause white matter injuries and persistent post-concussive symptoms (PPCS). We hypothesized that athletes with PPCS would have neurocognitive impairments and white matter abnormalities that could be revealed by advanced neuroimaging using ultra-high field strength diffusion tensor (DTI) and diffusion kurtosis (DKI) imaging metrics and cerebrospinal fluid (CSF) biomar

Between Delivery and Luck : Projectification of Academic Careers and Conflicting Notions of Worth at the Postdoc Level

This paper investigates how early career academics interpret and respond to institutional demands structured by projectification. Developing a ‘frame analytic’ approach, it explores projectification as a process constituted at the level of meaning-making. Building on 35 in-depth interviews with fixed-term scholars in political science and history, the findings show that respondents jointly referre

Decay Modes of Exotic Nuclei

This thesis presents advancements in studying exotic nuclei and rare decay modes through particle and γ-ray coincidence spectroscopy. The focus is on two experimental setups. First, complementing Compex Ge-detector modules with anti-Compton shields. Second, enhancing the Gammasphere-Microball setup at Argonne National Laboratory (ANL) with pixelated silicon detectors. These upgrades enable deeper

Making ‘it’ work : Nurses as essential linchpins in the home care context

Registered- and community health nurses in municipal home care (hereafter referred to as home care nurses) have a demanding job that is special compared to other forms of healthcare. The work is mobile, and care in the field is often carried out in solitude. At the same time, the patients being cared for often have complex care needs, requiring cooperation and interaction. Contact with colleagues Registered- and community health nurses in municipal home care (hereafter referred to as home care nurses) have a demanding job that is special compared to other forms of healthcare. The work is mobile, and care in the field is often carried out in solitude. At the same time, the patients being cared for often have complex care needs, requiring cooperation and interaction. Contact with colleagues

Health-related quality of life in patients with palmoplantar pustulosis–a Swedish register study

Background: Real-world data on health-related quality of life (HRQoL) in palmoplantar pustulosis (PPP) are scarce and few studies have analysed the generic HRQoL. Objectives: To assess HRQoL using the generic EQ-5D instrument and the Dermatology Life Quality Index (DLQI) instrument in PPP compared to plaque psoriasis. Methods: Cross-sectional data from PsoReg, the Swedish National Registry for Sys

Comparative Analysis of Pharmacokinetic-Pharmacodynamic Models for Propofol and Remifentanil Using Model Predictive Control

This study aims to compare the effectiveness of different Pharmacokinetic-Pharmacodynamic (PK-PD) models for administering Propofol and Remifentanil, two critical agents in anesthesia. Initially, different PK models were introduced: one for Propofol based on the Schnider model and another for Remifentanil using the Minto model. Alternatively, both drugs were modeled using the Eleveld models. The P

Critical needs to close monitoring gaps in pan-tropical wetland CH4 emissions

Global wetlands are the largest and most uncertain natural source of atmospheric methane (CH4). The FLUXNET-CH4 synthesis initiative has established a global network of flux tower infrastructure, offering valuable data products and fostering a dedicated community for the measurement and analysis of methane flux data. Existing studies using the FLUXNET-CH4 Community Product v1.0 have provided inval

Acoustic Trapping of Extracellular Vesicles

Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles released by cells. In the past two decades, EVs have gained a lot of attention due to their role in numerous biological processes. However, their small nature complicates isolating them from biological fluids with cumbersome techniques, such as ultracentrifugation. Acoustic trapping is a technique that uses ultrasonic stan

Extravert Surgical Resident Applicants Get Higher 360-Degree Evaluations From Coworkers

INTRODUCTION: 360-degree evaluations are used as an assessment in order to identify strengths and weaknesses of, or as a continuous evaluation for, residents. The aim of this study was to investigate the relationship between personality and ratings on 360-degree evaluations among surgical residency applicants. A secondary aim was to describe the personality profile of applicants for a surgical res