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Tumor extension in high-grade gliomas assessed with diffusion magnetic resonance imaging: values and lesion-to-brain ratios of apparent diffusion coefficient and fractional anisotropy.

Purpose: To determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema in gliomas from pure edema in meningiomas and metastases. Material and Methods: Thirty patients were studied: 18 WHO grade III or IV gliomas, 7 meningiomas, and 5 metastatic lesions. ADC and FA were determined from ROIs placed in peritumoral areas with T2-s

Expression of islet iNOS and inhibition of glucose stimulated insulin release after long-term lipid infusion in the rat is counteracted by PACAP27.

Chronic exposure of pancreatic islets to elevated plasma lipids ( lipotoxicity) can lead to beta-cell dysfunction, with overtime becoming irreversible. We examined, by confocal microscopy and biochemistry, whether the expression of islet inducible nitric oxide synthase ( iNOS) and the concomitant inhibition of glucose-stimulated insulin release seen after lipid infusion in rats was modulated by th

HIV/AIDS in the transitional countries of eastern Europe and central Asia

In the 1990s, HIV/AIDS became a major threat to health, economic stability and human development in countries in eastern Europe and central Asia. Social, political and economic transition exacerbated the structural conditions that allowed HIV/AIDS to flourish as dramatic changes led to increasing drug injection, economic decline and failing health and healthcare systems. There is a need to address

Further constructions of resilient Boolean functions with very high nonlinearity

One well-known method of generating key stream sequences for stream ciphers is to combine the outputs of several linear-feedback shift registers (LFSR) using a combining Boolean function. Here we concentrate on the design of good combining Boolean functions. We provide resilient Boolean functions with currently best known nonlinearity. These functions were not known earlier and the issues related

On the Determination of Reactive Compounds in Aerosols

Popular Abstract in Swedish Denna avhandling inom forskarutbildningsämnet arbetsmiljöteknik beskriver nyutvecklade provtagnings- och analysmetoder för att undersöka hur reaktionsbenägna luftföroreningar uppkommer och sprids i arbetsmiljön. Antalet människor som drabbas av allergier har ökat de senaste årtiondena. Många av de mekanismer som ger upphov till allergier och överkänslighetsreaktioner kMany sources of airborne contaminants have always been present in various work environments. With the development of thermosetting plastic systems, the use of reactive chemical compounds was greatly increased and thus also the risk of exposure to reactive and potentially hazardous compounds. Exposure can occur in many situations, not only at the workplace where the raw materials are handled. The f

Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry

Objectives: We studied the range in urinary levels of 2-thiothiazolidine-4-carboxyl acid (TTCA), a metabolite of CS, and phthalic acid (PA), a common metabolite of phthalates, across factories and departments in the contemporary rubber manufacturing industry. Methods: Spot urine samples from 101 rubber workers employed in nine different factories were collected on Sunday and during the workweek on

Development of strength and heat of hydration of young concrete at low temperature - influence of granulated blast furnace slag, silica and limestone

The work presented in this licentiate thesis was carried out within the project task Use of industrial by-products and filler in concrete, part Early-age strength development at low temperatures in concrete with mineral additions/fillers. To improve the understanding and to increase the data available, the study investigated the development of compressive strength and heat of hydration while curin

The effect on workload by using a support arm in parlour milking

Swedish agriculture is currently undergoing radical changes with respect to the working environment. New production milking systems may alter the physical workload and thus have an effect on the development of musculoskeletal disorders. Earlier studies have shown that there is a manifest risk of suffering injury to the forearm, wrist and hand during machine milking especially during the attaching

A biomimetic approach to artificial photosynthesis: Ru(II)-polypyridine photo-sensitisers linked to tyrosine and manganese electron donors

The paper describes recent advances towards the construction of functional mimics of the oxygen evolving complex in photosystem II (PSII) that are coupled to photoinduced charge separation. Some key principles of PSII and artificial systems for light-induced charge accumulation are discussed. Systems are described where biomimetic electron donors - manganese complexes and tyrosine - have been link

High rate of mutation reporter gene inactivation during human T cell proliferation.

Caspase activation and degradation of deoxyribonucleic acid (DNA) damage response factors occur during in vitro T-cell proliferation, and an increased frequency of hypoxanthine-guanine phosphoribosyltransferase (HPRT)-negative variants have been reported in conditions associated with in vivo T-cell proliferation. We have applied two human somatic cell mutation reporter assays, for the HPRT and pho